NIH-convened Expert Panel Proposes Standardized Definition of Placental COVID-19 Infection

NIH-convened Expert Panel Proposes Standardized Definition of Placental COVID-19 Infection

A panel of experts convened by the National Institutes of Health has recommended standardized criteria to define infection of the placenta with SARS-CoV-2, the virus that causes COVID-19. The panel also offers guidance... read more

Imputation Strategies for Missing Baseline Neurological Assessment Covariates After TBI

Imputation Strategies for Missing Baseline Neurological Assessment Covariates After TBI

Statistical models for outcome prediction are central to traumatic brain injury (TBI) research and critical to baseline risk adjustment. Glasgow coma score (GCS) and pupil reactivity are crucial covariates in all such models... read more

COVID-19, Online Shaming, and Health-care Professionals

COVID-19, Online Shaming, and Health-care Professionals

Stigma and shame have been features of past pandemics. The stigma associated with disease can be experienced as shame by those who spread it. In almost all human cultures, there is shame attached to being “contaminated”,... read more

Progressive Increase in Virulence of COVID-19 Variants

Progressive Increase in Virulence of COVID-19 Variants

The progressive increase in transmissibility and virulence of SARS-CoV-2 VOCs will result in a significantly larger, and more deadly, pandemic than would have occurred in the absence of variants of concern (VOC) emergence. The... read more

Artificial Intelligence Hold Promise in the ICU

Artificial Intelligence Hold Promise in the ICU

In a 2018 article entitled “Human Cognitive Limitations”, the University of Utah's Alan Morris estimated the number of variables an intensivist has to take into account for a patient on mechanical ventilation. He... read more

COVID-19: a boost for intensive care authorship?

COVID-19: a boost for intensive care authorship?

Almost 180 million cases of COVID-19 have been diagnosed, with almost 4.000.000 deaths. Since this pandemic had unprecedented worldwide healthcare and socio-economic effects, the scientific world is under exceptional pressure... read more

Effects of Early Mobilization on the Prognosis of Critically Ill Patients

Effects of Early Mobilization on the Prognosis of Critically Ill Patients

Early mobilization was effective in enhancing the recovery of critically ill patients, but more large-scale, multicenter randomized controlled trials are required to further confirm these findings. A total of 39 articles... read more

Multimorbidity on Long-Term Outcomes Following ICU Discharge

Multimorbidity on Long-Term Outcomes Following ICU Discharge

This national cohort study has demonstrated increased resource use for critical care survivors in the year following discharge but fails to replicate past findings of increased longer-term mortality. Multimorbidity, lifestyle... read more

Do Not Attempt CPR Decisions in People Admitted with Suspected COVID-19

Do Not Attempt CPR Decisions in People Admitted with Suspected COVID-19

Early do not attempt cardiopulmonary resuscitation (DNACPR) decisions were associated with recognised predictors of adverse outcome, and were inversely associated with Asian ethnicity. Most people with an early DNACPR decision... read more

Standardized post-resuscitation damage assessment of two mechanical chest compression devices

Standardized post-resuscitation damage assessment of two mechanical chest compression devices

The LUCAS 2 device shows superior resuscitation outcomes and less thoracic injuries compared to Corpuls cpr when used for experimental CPR in juvenile pigs. Researchers should be aware that different mCCDs for experimental... read more

A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients with COVID-19

A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients with COVID-19

Approximately, one in 20 patients hospitalized with coronavirus disease 2019 received resuscitation for an in-hospital cardiac arrest. Hospital survival after in-hospital cardiac arrest within the ICU was higher than non-ICU... read more

COVID-19 Pathophysiology: Looking Beyond Acute Disease

COVID-19 Pathophysiology: Looking Beyond Acute Disease

Careful descriptions of the clinical features of acute disease in patients infected with the novel coronavirus SARS-CoV-2 had begun to emerge before WHO declared the outbreak of COVID-19 a public health emergency of international... read more

Admission Hemoglobin Levels Are Associated With Functional Outcome in Spontaneous Intracerebral Hemorrhage

Admission Hemoglobin Levels Are Associated With Functional Outcome in Spontaneous Intracerebral Hemorrhage

Higher hemoglobin levels are associated with better outcome in intracerebral hemorrhage. Further research is needed to evaluate admission hemoglobin levels as both a therapeutic target and predictor of outcome. Our exposure... read more

Virtual Reality Tailored to the Needs of Post-ICU Patients

Virtual Reality Tailored to the Needs of Post-ICU Patients

ICU-specific virtual reality appears safe and more immersive than 2D, implicating that ICU-specific virtual reality is feasible for clinical use. One should however be aware of simulator sickness-related symptoms. Future... read more