HSV-1 Reactivation Associated with Increased Mortality Risk and Pneumonia in COVID-19 Patients

HSV-1 Reactivation Associated with Increased Mortality Risk and Pneumonia in COVID-19 Patients

Critically ill COVID-19 patients frequently reactivate HSV-1 but not HSV-2. HSV-1 reactivation in critically ill COVID-19 patients was associated with an increased risk of day-60 mortality and hospital-acquired pneumonia... read more

Cancer Clues In A Drop Of Blood

Cancer Clues In A Drop Of Blood

New diagnostic blood test paves the way for early stage lung cancer screening. A diagnostic blood test may provide early detection of lung cancer in asymptomatic patients, according to a new study. Lung cancer, the leading... read more

Clinical Synopsis of COVID-19: Evolving and Challenging

Clinical Synopsis of COVID-19: Evolving and Challenging

Coronavirus disease or COVID-19 or SARS-CoV-2 infection is the latest pandemic that has affected humans globally. The disease has manifested itself in several forms and is now the focus of research worldwide. This book... read more

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are... read more

Semiquantitative Assessment of RFV with a Modified Subcostal Echocardiographic View

Semiquantitative Assessment of RFV with a Modified Subcostal Echocardiographic View

In patients presenting with RVF in the ICU (or in situations where the apical echocardiographic view is suboptimal for tricuspid annular assessment), SEATAK can be an alternative to TAPSE. Further research is needed to validate... read more

Post COVID-19 and Patients with and without Pre-existing ILD

Post COVID-19 and Patients with and without Pre-existing ILD

A lot remains to be learned about the long-term effects of patients with interstitial lung disease (ILD) who survive COVID-19 infections. Clinicians need to better understand and recognize the effects of post-COVID 19 lung... read more

Mortality and Clinical Characteristics of MIS-C Associated with COVID-19

Mortality and Clinical Characteristics of MIS-C Associated with COVID-19

The clinical presentation and severity of Multisystem Inflammatory Syndrome in Children associated with COVID-19 (MIS-C) is widespread and presents a very low mortality rate in high-income countries. This research describes... read more

Difference in Sepsis Patients Outcomes Between First and Second-Hit Infections

Difference in Sepsis Patients Outcomes Between First and Second-Hit Infections

Our study identifies a fundamental difference in patient outcomes between first-hit and second-hit bacterial infections, which may be due to genetic, microbiological, immunological, and environmental factors. This finding... read more

Impact of Tight Glucose Control on Circulating 3-hydroxybutyrate in Critically Ill Patients

Impact of Tight Glucose Control on Circulating 3-hydroxybutyrate in Critically Ill Patients

Tight versus liberal glucose control in the context of early parenteral nutrition did not affect 3-hydroxybutyrate concentrations in critically ill patients. Hence, the protective effects of tight glucose control in this... read more

State of the Art Techniques in Critical Care Echocardiography

State of the Art Techniques in Critical Care Echocardiography

This book covers all aspects of modern techniques used in the rapidly developing field of adult critical care echocardiography, 3D transthoracic and transesophageal echocardiography, myocardial tissue velocity and deformation... read more

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients

Sleep in intensive care is hampered due to many factors; the clinical environment itself exacerbates sleep disturbance. Research suggests that interventions aimed at improving sleep quality have produced positive effects... read more

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest

In comatose survivors of out-of-hospital cardiac arrest, a target temperature of 31 °C did not significantly reduce the rate of death or poor neurologic outcome at 180 days compared with a target temperature of 34 °C. However,... read more

Emerging Advances have the Potential to Change the Future of Sepsis Care

Emerging Advances have the Potential to Change the Future of Sepsis Care

In recent years, many advances in the sepsis literature have occurred, including new definitions, changes to the Surviving Sepsis Campaign (SSC) bundles, new pharmacologic agents, and adjunct treatments. There are also... read more

Diagnostic Errors in Pediatric Critical Care

Diagnostic Errors in Pediatric Critical Care

Knowledge of diagnostic errors in the PICU is limited. Future work to understand diagnostic errors should involve a balanced focus between studying the diagnosis of individual diseases and uncovering common system- and process-related... read more