Lactated Ringer’s a Clear Winner for Pancreatitis Resuscitation

Pancreatitis, a common and challenging condition, presents frequently in emergency departments across the country, affecting around 34 of every 100,000 adults annually. This often-severe disease is marked by inflammation... read more

Outcomes of Older Adults With Sepsis at Admission to an ICU

Our study suggests that treating older adults with therapies recommended by the Surviving Sepsis Campaign may improve outcomes in this age group, although mortality remains high for older adults with sepsis. In addition,... read more

Rethinking Energy and Protein Provision for Critically Ill Patients

In critically ill patients, we suggest that energy and protein be delivered progressively in stable or recovering patients. If a patient deteriorates, regardless of days spent in the ICU, low-dose energy and protein should... read more

A Perspective on Post-Cardiac Arrest Syndrome

This book presents a valuable new perspective on Post-Cardiac Arrest Syndrome (PCAS), which was defined as system failure following whole-body ischemia-reperfusion injuries by the 2008 International Liaison Committee on Resuscitation.... read more

A Perspective on Post-Cardiac Arrest Syndrome

Thrombocytopenia and COVID-19 pairing in the ICU: Prognostic influence of thrombocytopenia in resuscitated CoViD-19 patients

CoViD-19 is a viral zoonosis caused by the coronavirus strain (SARS-CoV-2), with acute respiratory failure being its most severe manifestation. Our aim was to determine the influence of thrombocytopenia on the severity and... read more

Thrombocytopenia and COVID-19 pairing in the ICU: Prognostic influence of thrombocytopenia in resuscitated CoViD-19 patients

Pediatric Critical Care: A Primer for All Clinicians

Pediatric critical care is an emotionally and intellectually demanding field of medicine; however, it is at its core the discipline focused on saving and improving the lives of children affected by acute and chronic illnesses,... read more

Pediatric Critical Care: A Primer for All Clinicians

Resuscitation Arterial Waveform Quantification and Outcomes in Pediatric Patients

Providing physiologically adequate CPR for pediatric single ventricle patients palliated with Bidirectional Glenn (BDG) or Fontan physiology is challenging. Only 27% of Fontan patients survived to hospital discharge with... read more

Fluid boluses and infusions in the early phase of resuscitation from septic shock and sepsis-induced hypotension

Fluid administration is the first line treatment in intensive care unit (ICU) patients with sepsis and septic shock. While fluid boluses administration can be titrated by predicting preload dependency, the amount of other... read more

Effect of Different Shock Conditions on Mesenteric Hemodynamics

The velocity parameters of SMA Doppler ultrasound such as TAMV and PSV can reflect cardiac function. The measurements of SMA RI and PI are correlated with lactate levels, having a positive predictive value for hyperlactatemia... read more

Fluid Accumulation Syndrome in Sepsis and Septic Shock

In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS)... read more

Vasoconstriction in Septic Shock

Septic shock is associated with endothelial dysfunction leading to arterial and venous dilation, alterations in regional blood flow distribution, and microcirculatory disturbances. Fluids and vasopressors are the key... read more

Fluid Boluses May Improve CRT

Several studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT monitoring during septic shock resuscitation. Therefore, it is relevant to further explore... read more

Fluid Personalization and Vasopressor Decisions in Early Sepsis Management

In this randomized vignette survey study of US critical care clinicians, we found that fluid volume already received was associated with the largest changes in decisions to administer additional fluids or initiate vasopressors... read more

Traumatic Major Hemorrhage in a Tertiary Trauma Center

Major traumatic hemorrhage is potentially preventable with rapid hemorrhage control and improved resuscitation techniques. The time from injury to hospital, resuscitation, diagnosis, and definitive bleeding control should... read more

Damage Control Resuscitation: Identification and Treatment of Life-Threatening Hemorrhage

This book provides a comprehensive overview of damage control resuscitation (DCR), an evidence-based approach to the resuscitation of patients with severe life-threatening hemorrhage (LTH). It focuses on both civilian... read more

Damage Control Resuscitation: Identification and Treatment of Life-Threatening Hemorrhage

ECPR for Hypothermic Refractory Cardiac Arrests in Temperate Climates

Accidental hypothermia designates an unintentional drop in body temperature below 35 °C. There is a major risk of ventricular fibrillation below 28 °C and cardiac arrest is almost inevitable below 24 °C. In such cases,... read more

Feasibility of HEMS Performed Prehospital E-CPR in Pediatric Cardiac Arrests

This case-series shows that a properly trained regular Helicopter Emergency Medical Services (HEMS) crew of only two health care professionals (doctor and flight nurse) can establish Extracorporeal-Cardiopulmonary Resuscitation... read more

Doppler Ultrasound Identified Venous Congestion in Septic Shock

Venous congestion is a pathophysiological state where high venous pressures cause organ edema and dysfunction. Venous congestion is associated with worse outcomes, particularly acute kidney injury (AKI), for critically ill... read more

Optimal Fluid Therapy for Sepsis Management in Critically Ill Adults

For a study, researchers aimed to analyze the fluid treatment in septic critically ill adults. About 20% to 30% of patients were admitted to an ICU with sepsis. In sepsis patients, investigators observed intravenous fluid... read more

Checklists and Consistency of Care After Resuscitation From IHCA

In-hospital cardiac arrest (IHCA) with the return of spontaneous circulation (ROSC) is a clinical scenario associated with potentially devastating outcomes. Our study demonstrated improved consistency in completing post-ROSC... read more

VA-ECMO in High-Risk Pulmonary Embolism

High-risk Pulmonary Embolism (PE) has an ominous prognosis and requires emergent reperfusion therapy, primarily systemic thrombolysis (ST). In deteriorating patients or with contraindications to ST, Veno-Arterial Extracorporeal... read more