Intranasal Dexmedetomidine vs. Inhaled Nitrous Oxide for Pediatric Procedural Sedation and Analgesia

The results of this clinical trial support that IN DEX is not inferior to 50% nitrous oxide in providing analgesia for a painful procedure among children 3–15 years of age. Furthermore, IN DEX can be considered as an alternative... read more

Severe ICU-Acquired Hypernatremia: Prevalence, Risk Factors, Trajectory, Management, and Outcome

Severe hypernatremia occurred in the setting of inability to drink, near-absent measurement of urinary free water losses, diuretic therapy, fever, renal impairment, and near-absent or limited or delayed water administration.... read more

Awake, Walking, and Intubated – The ICU Breakthrough Giving Patients Their Lives Back

If they knew what it's like for patients surviving after the ICU, that sedation isn't sleep, and that they're being so traumatized and damaged by these normal practices, they would change this. Picture this: it's your... read more

Early Deep-to-light vs. Continuous Light Sedation for ICU Patients with Mechanical Ventilation

Compared to the continuous light sedation, early deep-to-light sedation strategy was associated with improved patient outcomes, and continuous deep sedation was confirmed with poorer patient outcomes. In total, 6700 patients... read more

Reducing Deep Sedation and Benzodiazepine Use in Mechanically Ventilated Patients During Critical Care Transport

The rate of deep sedation in this cohort was consistent with previously published data; however, it remains higher than clinically indicated. Over the course of the QI project, the proportion of deeply sedated patients... read more

Bedside Procedures in the ICU

Bedside Procedures in the ICU

This handbook is a guide to best practice in interventions commonly encountered in the ICU. It is clinically orientated providing step-by-step explanations and illustrations of most invasive procedures, check lists to make... read more

Early Reapplication of Prone Position During VV-ECMO for ARDS

A combination of prone positioning (PP) and venovenous extracorporeal membrane oxygenation (VV-ECMO) is safe, feasible, and associated with potentially improved survival for severe acute respiratory distress syndrome (ARDS).... read more

How to end quiet suffering in the ICU? Identifying and treating hypoactive delirium

The duration of time a person spends in hypoactive delirium predicts higher rates of death, longer length of stay, higher costs of care, and higher rates of acquired dementia in the months and years following critical illness.... read more

Ketamine for Treatment-Resistant Depression

Ketamine for Treatment-Resistant Depression

This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine... read more

Moderate and Deep Sedation in Clinical Practice

Moderate and Deep Sedation in Clinical Practice

Millions of procedures requiring sedation are performed each year, covering a large array of medical specialties in both inpatient and outpatient settings. This tremendous growth has led to sedation being administered by... read more

Impact of a Rounding Checklist Implementation in the Trauma ICU on Clinical Outcomes

Impact of a Rounding Checklist Implementation in the Trauma ICU on Clinical Outcomes

We aimed to evaluate the effectiveness of an intensive care unit (ICU) round checklist, FAST HUGS BID (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head-of-bed elevation, Ulcer prophylaxis, Glycemic control,... read more

Handbook of Evidence-Based Critical Care

Handbook of Evidence-Based Critical Care

This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding... read more

EEG Patterns for Predicting Poor Outcome After Cardiac Arrest

EEG Patterns for Predicting Poor Outcome After Cardiac Arrest

The specificity of the ERC-ESICM-recommended EEG patterns for predicting poor outcome after cardiac arrest exceeds 90% but is lower than in previous studies, suggesting that large-scale implementation may reduce their accuracy.... read more

Ineffective Airway Clearance Nursing Diagnosis & Care Plans

Ineffective Airway Clearance Nursing Diagnosis & Care Plans

Ineffective airway clearance is the inability to clear secretions or obstructions from the respiratory tract. This can be detrimental to breathing and create complications. Secretions can be problematic as a result of... read more

Scheduled Intravenous Opioids

Scheduled Intravenous Opioids

Maintaining comfort and analgesia is fundamental to providing adequate care in intensive care unit (ICU) patients. Pain assessment and its control remain the highest priorities and concerns among survivors of critical illness... read more

Propofol-Related Infusion Syndrome in a Child with RSE

Propofol-Related Infusion Syndrome in a Child with RSE

Propofol is used for sedation, anxiolysis, anesthesia induction, and as an anticonvulsant. In cases of refractory status epilepticus (RSE), propofol is more efficient than barbiturates. We present a case of a 3-year-old... read more

Haloperidol Efficacy to Decrease Delirium Burden in Critically Ill Patients

Haloperidol Efficacy to Decrease Delirium Burden in Critically Ill Patients

This trial, that was stopped early, did not show evidence that haloperidol reduces delirium and coma in critically ill patients with delirium. The beneficial effects on some agitation-related outcomes and lower sedative... read more