Bronchoscopy in ICU: A Practical Guide

Bronchoscopy in ICU: A Practical Guide

This practical guide focuses on Bronchoscopy in ICU. Bronchoscopy is one of the most commonly performed medical procedures, but is limited to the practice of a handful chest physicians and surgeons. The field of bronchoscopy... read more

Ciprofol Sedation Efficacy and Safety in Mechanical Ventilated ICU Patients

Ciprofol Sedation Efficacy and Safety in Mechanical Ventilated ICU Patients

Ciprofol was well tolerated, with a noninferior sedation profile to propofol in Chinese ICU patients undergoing MV for a period of 6–24 hours. Of the 135 patients enrolled, 129 completed the study. The primary endpoint-sedation... read more

Critical Care Sedation

Critical Care Sedation

This book provides a comprehensive guide to delivering analgesia and sedation to critically ill patients for professionals and caregivers being involved in the management of these patients. It discusses and explains in... read more

Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

This book covers all clinical aspects of acute respiratory distress syndrome (ARDS), from definition to treatment, focusing on the more recent recommendations and evidence-based medicine. The addressed topics are the... read more

Dexmedetomidine, Almost As Many Uses As There Are Letters

Dexmedetomidine, Almost As Many Uses As There Are Letters

There is literature to support the use of dexmedetomidine in patients with sympathomimetic toxidrome. It may be a reasonable approach to utilize Dex, with or without a bolus, while closely monitoring these patients in an... read more

Lung and Diaphragm Protective Ventilation Guided by the Esophageal Pressure

Lung and Diaphragm Protective Ventilation Guided by the Esophageal Pressure

Lung protective ventilatory strategies aim to limit tidal volume, driving pressure and plateau pressure to minimize lung stress and strain and consequently reduce the morbidity and mortality risks associated with mechanical... read more

Dexmedetomidine vs. Propofol Sedation in Critically Ill Adults Requiring Mechanical Ventilation

Dexmedetomidine vs. Propofol Sedation in Critically Ill Adults Requiring Mechanical Ventilation

Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and the risk of delirium in cardiac surgical patients. It also significantly... read more

Bedside Procedures in the ICU

Bedside Procedures in the ICU

This handbook is a guide to best practice in interventions commonly encountered in the ICU. It is clinically orientated providing step-by-step explanations and illustrations of most invasive procedures, check lists to make... read more

Sedation Management Evolution in the ICU

Sedation Management Evolution in the ICU

This paper provided an overview of how ICU sedation practices have evolved over the last 20 years. Contemporary ICU sedation practices include light levels of sedation, SAT, and use of non-benzodiazepines. The current... read more

Prevalence of PICS in Mechanically Ventilated Patients with COVID-19

Prevalence of PICS in Mechanically Ventilated Patients with COVID-19

Coronavirus disease 19 (COVID-19) patients usually require long periods of mechanical ventilation and sedation, which added to steroid therapy, favours a predisposition to the development of delirium and subsequent mental... read more

Moderate Procedural Sedation and Analgesia

Moderate Procedural Sedation and Analgesia

Introducing the definitive resource designed for practitioners working in the rapidly expanding area of moderate procedural sedation and analgesia clinical practice. Moderate Procedural Sedation and Analgesia: A Question... read more

General Anesthesia vs. Sedation Using Hemodynamic Control During Intraarterial Treatment for Stroke

General Anesthesia vs. Sedation Using Hemodynamic Control During Intraarterial Treatment for Stroke

The functional outcomes 3 months after endovascular treatment for stroke were similar with general anesthesia and sedation. Our results, therefore, suggest that clinicians can use either approach. Of 351 randomized patients,... read more

Music Therapy Intervention to Treat Sedation-Related Delirium in Critical Care

Music Therapy Intervention to Treat Sedation-Related Delirium in Critical Care

Sedation is an essential component of treatment for some patients admitted to the intensive care unit, but it carries a risk of sedation-related delirium. Sedation-related delirium is associated with higher mortality and... read more

Melatonin in ICU Delirium: Shining Light on the Hormone of Darkness

Melatonin in ICU Delirium: Shining Light on the Hormone of Darkness

Delirium represents a form of acute brain dysfunction predictive of excess death and long-term cognitive impairment in critically ill patients. For many years, we have wondered whether pharmacological doses of melatonin would... read more