Postintubation Sedation Administration in the Pediatric ED

Postintubation Sedation Administration in the Pediatric ED

Most pediatric patients do not receive PIS within an adequate time frame. Patients who receive long-acting paralytic agents are much less likely to be adequately sedated after rapid sequence intubation (RSI) compared with... read more

The Reemergence of Ketamine for Treatment in Critically Ill Adults

The Reemergence of Ketamine for Treatment in Critically Ill Adults

Ketamine has suggested potential benefit in several disease states impacting critically ill patients including pain, alcohol withdrawal syndrome, status epilepticus, and acute agitation. Further supporting evidence is needed... read more

Ketamine vs. Nonketamine Regimens for Analgosedation in the ICU

Ketamine vs. Nonketamine Regimens for Analgosedation in the ICU

Results suggest ketamine as an adjunct analgosedative has the potential to reduce opioid exposure in postoperative and MV patients in the ICU. More RCTs are required before recommending routine use of ketamine in select populations. A... read more

Patients Discharged From the ICU on a Dopamine Infusion

Patients Discharged From the ICU on a Dopamine Infusion

Despite a higher ICU readmission rate, ICU discharge of patients on dopamine infusion was not associated with increased mortality. The hospital mortality rate was comparable in both groups, despite that the median logistic... read more

Discordance Between Respiratory Drive and Sedation Depth in Critically Ill Patients Receiving Mechanical Ventilation

Discordance Between Respiratory Drive and Sedation Depth in Critically Ill Patients Receiving Mechanical Ventilation

Sedation depth is not a reliable marker of respiratory drive during critical illness. Respiratory drive can be low, moderate, or high across the range of routinely targeted sedation depth. 56 patients undergoing 197 bedside... read more

Floating Feathers: A Doctor’s Harrowing Experience as a Patient Within Conventional Medicine and an Impassioned Call for the Future of Care in America

Floating Feathers: A Doctor’s Harrowing Experience as a Patient Within Conventional Medicine and an Impassioned Call for the Future of Care in America

Dr. Ross I.S. Zbar spent his career as a plastic surgeon, in the US as well as abroad in developing countries, mending disease- and trauma-related deformities--and he was never hesitant to make his voice heard as an advocate... read more

Sedation Practices and Characteristics of Ventilated Patients

Sedation Practices and Characteristics of Ventilated Patients

Patients on mechanical ventilator experience anxiety and physiological stress. Sedating them can help those patients to cope up with ET tube, to bear all the interventions, for accessing adequate oxygenation and above... read more

Inhaled Sedation in the ICU: A New Option and Its Technical Prerequisites

Inhaled Sedation in the ICU: A New Option and Its Technical Prerequisites

Andreas Meiser summarizes the current literature on inhalation sedation of critically ill patients. To meet clinical demands, he describes the development of new devices to administer volatile anesthetics together with common... read more

Clinical Trials Design Evaluating Sedation in Critically Ill Adults Requiring Mechanical Ventilation

Clinical Trials Design Evaluating Sedation in Critically Ill Adults Requiring Mechanical Ventilation

These recommendations are intended to assist researchers in the design, conduct, selection of endpoints, and reporting of clinical trials involving sedative medications and/or sedation protocols for adult ICU patients who... read more

Melatonin for Delirium Prevention in Hospitalized Patients

Melatonin for Delirium Prevention in Hospitalized Patients

Melatonin/ramelteon are associated with reduction in delirium incidence in hospitalized patients. However, this effect seems confined to surgical and ICU patients. The optimum dosage and formulation of melatonin, and... read more

The Relationship of Delirium, Sedation, Dementia, and Acquired Weakness

The Relationship of Delirium, Sedation, Dementia, and Acquired Weakness

The advent of modern critical care medicine has revolutionized care of the critically ill patient in the last 50 years. The Society of Critical Care Medicine (was formed in recognition of the challenges and need for specialized... read more

Higher Level of Mobilization Improves Health Status

Higher Level of Mobilization Improves Health Status

In critically ill survivors, achieving higher levels of mobilization, but not increasing the number of active mobilization sessions, improved health status 6 months after ICU admission. The dosage of mobilization in ICU... read more

Percutaneous Ultrasound Guided Gastrostomy Tube Placement

Percutaneous Ultrasound Guided Gastrostomy Tube Placement

Percutaneous ultrasound guided gastrostomy (PUG) is similar in terms of complications to percutaneous gastrostomy tube (PRG) placement and a safe method for gastrostomy tube placement in the critically ill with the added... read more

Checklist for Early Recognition and Treatment of Acute Illness and Injury

Checklist for Early Recognition and Treatment of Acute Illness and Injury

A quality-improvement intervention with remote simulation training to implement a decision support tool was associated with decreased nonadherence to daily care processes, shorter length of stay, and decreased mortality. The... read more