Hospitals struggle to address terrifying and long-lasting 'ICU delirium'

Doctors and nurses across the country are now pushing an ambitious campaign to change practices in intensive care units to reduce cases of "ICU delirium".... read more

Hospitals struggle to address terrifying and long-lasting 'ICU delirium'

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

In sepsis-associated ARDS, hydrocortisone treatment was associated with a significant improvement in pulmonary physiology, but without a significant survival benefit.... read more

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

Levosimendan Doesn’t Prevent Acute Organ Dysfunction

For adults with sepsis, levosimendan does not prevent acute organ dysfunction.... read more

Levosimendan Doesn’t Prevent Acute Organ Dysfunction

Empirical micafungin treatment doesn't improve survival

Empirical treatment with micafungin seems not to increase invasive fungal infection (IFI)-free survival at 28 days for patients with intensive care unit (ICU)-acquired sepsis with Candida colonization.... read more

Empirical micafungin treatment doesn't improve survival

Hydrocortisone and Septic Shock in Patients With Severe Sepsis

This randomized clinical trial compares the effects of hydrocortisone vs placebo on development of septic shock among intensive care patients with severe sepsis who were not in septic shock.... read more

Hydrocortisone and Septic Shock in Patients With Severe Sepsis

Should we treat pyrexia? And how do we do it?

Pyrexia has long been thought of as a protective physiological response to help host defences, although this is now being challenged. Despite recent advances, it remains unclear whether pyrexia or the physiological response... read more

Should we treat pyrexia? And how do we do it?

Association of Sodium Selenite and Procalcitonin-Guided Therapy With Mortality

This randomized clinical trial evaluates the use of high-dose sodium selenite, with or without use of a procalcitonin algorithm to guide therapy, and its association with mortality in patients with severe sepsis.... read more

Association of Sodium Selenite and Procalcitonin-Guided Therapy With Mortality

Beta-Lactam Infusion in Severe Sepsis (BLISS)

Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis.... read more

Beta-Lactam Infusion in Severe Sepsis (BLISS)

Sentinel, a Next Generation Life-Saving Sepsis Alerting Solution

Uniphy Health - a leader in mobile solutions for clinical collaboration and communications - today announced the wide-scale availability of its Sentinel sepsis alerting solution. Uniphy Sentinel is being deployed on the Uniphy... read more

Sentinel, a Next Generation Life-Saving Sepsis Alerting Solution

Belgian scientists discover missing link in septic shock

Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body’s immune system to an infection.... read more

Belgian scientists discover missing link in septic shock

Researchers tap Mayo, Christiana Care EHR data to fight sepsis

In an effort to improve the diagnosis and treatment of sepsis, records data will be used to help understand how to beat the disease. ... read more

Researchers tap Mayo, Christiana Care EHR data to fight sepsis

Long-Term Quality of Life Among Survivors of Severe Sepsis

Severe sepsis currently accounts for 10% of all intensive care unit admissions and is the leading cause of death in U.S. hospitals. Studies have shown that sepsis survivors suffer from many long-term after-effects.... read more

AF in Sepsis: Choosing the Right Therapy

It seems that during almost every intensive care unit shift, at least one patient goes into atrial fibrillation (AF). There are several treatment options, including calcium channel blockers (CCBs), beta-blockers (BBs), digoxin,... read more

AF in Sepsis: Choosing the Right Therapy

Doctors, hospitals, advocates push for education on killer sepsis

Many people don't know about sepsis. Meanwhile, health care providers struggle to identify it early. Sepsis kills more than 250,000 people every year; people at highest risk are those with weakened immune systems.... read more

Doctors, hospitals, advocates push for education on killer sepsis

Is SIRS dead? The new definition of sepsis.

To mark Sepsis Awareness Month in September, Prof Gando, Editor-in-Chief of Journal of Intensive Care, tells us more about the recent sepsis definitions, published earlier this year.... read more

Is SIRS dead? The new definition of sepsis.

N.J. hospitals work together to reduce sepsis deaths

Anyone can get sepsis. They can get it while perfectly healthy, after having a health issue or while hospitalized for a procedure or test.... read more

N.J. hospitals work together to reduce sepsis deaths

VIB-Ghent University research provides insights into septic shock

Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body's immune system to an infection.... read more

VIB-Ghent University research provides insights into septic shock

Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials

Ludwig Lin, MD, speaks with Sachin Yende, MD, MS, about his article, "Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials," published in Critical Care Medicine.... read more

Utilising the immune system in the fight against sepsis – On Medicine

In this blog, Dr. Naoshi Takeyama, Senior Editor of Journal of Intensive Care, discusses about how knowledge of immuno-oncology can also be applied to strategies for managing sepsis and severe trauma.... read more

Utilising the immune system in the fight against sepsis – On Medicine

Researchers map links between salmonella, sepsis

Research by industrial engineering and biology researchers marks a significant milestone in the battle against sepsis, the second highest cause of death in intensive care units in the U.S.... read more

Researchers map links between salmonella, sepsis

Latest sepsis research for health care providers

The syndrome, caused by "the body's overwhelming and life-threatening response to infection, which can lead to tissue damage, organ failure, and death," can be difficult to predict, diagnose and treat, according... read more

Latest sepsis research for health care providers