Tag: study
Prevalence and Outcomes of Shock in Internal Medicine Patients
This retrospective observational study investigated the incidence, management, and outcomes of 125 shock patients admitted to the internal medicine department of a referral university hospital in Bangkok, Thailand, addressing... read more
Severe Listeriosis in the ICU: Critical Insights from a Multicenter Study
A retrospective multicenter study across 23 French hospitals over 10 years analyzed critically ill ICU patients with culture-confirmed "Listeria monocytogenes" infections. The study aimed to describe patient characteristics,... read more
Push-Dose Epinephrine Use in the Emergency Department
A retrospective multi-site cohort study investigated the use of push-dose epinephrine (PDE) in emergency departments (EDs) for managing hypotension in critically ill patients. Recognizing the limited ED-specific data compared... read more
Evaluating Remimazolam for ED Procedural Sedation Effectiveness and Patient Satisfaction
This study evaluated the safety and efficacy of remimazolam, an ultra-short acting benzodiazepine, for procedural sedation in the emergency department (ED). The primary aim was to compare its administration by emergency medicine... read more
Comparing Outcomes of COVID-19 and Influenza in Hospitalized European Adults
A study conducted through the EuroSAVE Network from December 2021 to March 2024 in five European middle-income countries/areas compared the odds of severe outcomes and death among hospitalized patients meeting the WHO severe... read more
Vitamin D Dynamics in Severe ARDS Patients on ECMO
This retrospective study investigated time-dependent changes in vitamin D levels and their correlation with disease severity and inflammation in 24 invasively mechanically ventilated patients with acute respiratory distress... read more
Troponin HsTnI: Predicting Outcomes in Covid-19 Patients
This observational retrospective cohort study of 325 patients diagnosed with COVID-19 aimed to determine the relationship between troponin levels and disease severity or mortality. Conducted at Mohammed VI CHU in Oujda... read more
Early Multimodal Rehabilitation Safely Accelerates Recovery for Ventilated Patients
This single-center, controlled clinical trial investigates the efficacy and safety of an early multimodal rehabilitation program (MRP) versus a late MRP in mechanically ventilated adult patients in the intensive care unit... read more
Causes of Death in Patients Undergoing ECPR
Refractory shock was the leading cause of death among our cohort of extracorporeal cardiopulmonary resuscitation (ECPR) patients, followed closely by neurological complications, while other causes are rare. In this post-hoc... read more
Mechanical Power Impact Normalized to Predicted Body Weight on Outcomes in Pediatric ARDS
Higher mechanical power (MP) was associated with fewer ventilator (VFD) and ICU free days (IFD). The causal effect of MP on VFD and IFD was fully mediated by the impairment in oxygenation. This is a post-hoc analysis of... read more
Anticoagulation Reversal Strategies for Warfarin Associated Acute Gastrointestinal Bleeding
Patients who received prothrombin complex concentrate (PCC) had a threefold increase in mortality compared to fresh frozen plasma (FFP), vitamin K alone, or no reversal, even after adjusting for severity of the bleeding.... read more
Endotracheal Tube Cuff Pressure Monitoring and VAP Occurrence
This study demonstrated that maintaining endotracheal tube cuff pressure at 30 cm H2O through monitoring every 8 h did not result in a greater incidence of under-inflation (pressures ... read more
Hemodynamic Stabilization Using CRRT and cIVNa Combination Therapy
Compared with conventional continuous renal replacement therapy (CRRT), combination therapy of CRRT and continuous intravenous sodium infusion therapy (cIVNa) increased blood pressure, enhanced urinary volume, and reduced... read more
A Novel Mechanism for COVID-19 Related Thrombotic Events: Platelet NO/ROS Equilibrium
The finding that platelet NO/ROS production imbalance contributes to the elevated risk of thrombotic events in COVID-19 has important clinical implications. Restoration of platelet NO production, as well as attenuation... read more
Inadequate Empirical Antibiotic Therapy in VAP: Risk Factors and Outcomes
Ventilator-associated pneumonia (VAP) caused by MDR pathogens were highly likely to receive inadequate empirical antibiotic therapy. The mortality rate and intubation duration were significantly longer in inadequately treated... read more
Early Acetaminophen Administration Associated with Lower Mortality Among ARDS Patients After Coronary Artery Bypass Grafting
The use of acetaminophen (APAP) at 48h after coronary artery bypass grafting (CABG)-acute respiratory distress syndrome (CABG-ARDS) was associated with lower early postoperative mortality, while shortening the length of hospital... read more
Thirst Management in Orotracheally Intubated and Mechanically Ventilated Patients
Symptom Management Theory (SMT)-based thirst management is an effective strategy. The 5 mL cold water spray method significantly reduces thirst intensity and distress in mechanically ventilated patients under fasting and... read more
Serum MANF vs. Severity and Prognosis in Community-acquired Pneumonia Patients
This evidence demonstrated that serum mesencephalic astrocyte-derived neurotrophic factor (MANF) is positively associated with scoring criteria and poor prognosis in community-acquired pneumonia (CAP) patients. Serum... read more
Tocilizumab vs. IVIG in Patients with Severe COVID-19 Pneumonia
Severe COVID-19 patients who received IVIG in the early phase of the disease did not show better clinical outcomes in terms of mortality, hospitalization time and intensive care unit admission compared to those who received... read more
Levosimendan Role in ECMO for Refractory Cardiac Arrest
Levosimendan use in extracorporeal cardiopulmonary resuscitation (ECPR) did not improve survival. Neurological outcome could be representative of the short- and long-term outcomes. Future well-designed randomized trials... read more
Fever Management with or without a Temperature Control Device After OHCA and Resuscitation
the TEMP‐CARE trial will advance our understanding of post‐cardiac arrest care fever management strategies. With a large sample size and a broad patient population, the results of this trial will inform clinical practice... read more
Femoral Head Osteonecrosis in Post-COVID-19 Patients
This study provides an insight into the relationship between COVID-19-related factors and the development of osteonecrosis of the femoral head (ONFH), emphasizing the critical role of cumulative steroid dose as the primary... read more
