Tag: study
Early Tracheostomy in Ventilated COVID-19 Patients Reduces VAP Incidence
Tracheostomy can reduce mechanical ventilation (MV) duration, ICU and hospital length of stay (LOS), and ventilator-associated pneumonia (VAP) risk in critically ill patients. The timing of tracheostomy in COVID-19 patients... read more
Intranasal Dexmedetomidine vs. Inhaled Nitrous Oxide for Pediatric Procedural Sedation and Analgesia
The results of this clinical trial support that IN DEX is not inferior to 50% nitrous oxide in providing analgesia for a painful procedure among children 3–15 years of age. Furthermore, IN DEX can be considered as an alternative... read more
Antibiotic prophylaxis reduced broad-spectrum antibiotics and length of stay in ICU patients with alcohol withdrawal induced refractory delirium tremens
Administration of TMP-SMX prophylaxis reduced the use of broad-spectrum antibiotics and ICU LOS in ICU-treated rDT patients. The retrospective study design should be considered when interpreting the results, and prospective... read more
Severe ICU-Acquired Hypernatremia: Prevalence, Risk Factors, Trajectory, Management, and Outcome
Severe hypernatremia occurred in the setting of inability to drink, near-absent measurement of urinary free water losses, diuretic therapy, fever, renal impairment, and near-absent or limited or delayed water administration.... read more
Non-Intensive Care Unit Feasibility for Ambulatory VV-ECMO Patients
Our data suggests that ambulatory veno-venous extracorporeal membrane oxygenation (VV-ECMO) patients may tolerate less than ICU level of care and may even progress to outpatient management as ECMO technology continues to... read more
Dexmedetomidine for Electroencephalogram in Children with Behavioural Disorders
Intranasal (IN) dexmedetomidine (DEX) is an effective sedative; its recovery time shorter than IV DEX and its favorable adverse events profile make this route a reasonable alternative, especially in pediatric patients with... read more
Impacts of Initial ICU Driving Pressure on Outcomes in Acute Hypoxemic Respiratory Failure
Driving pressure (DP) is a marker of severity of lung injury in patients with acute respiratory distress syndrome (ARDS) and has a strong association with outcome. However, it is uncertain whether limiting DP can reduce... read more
Effects of Surgery on Hemodynamics and Postoperative Delirium in Stanford Type A Aortic Dissection
The results of this study indicate that surgical intervention has a significant effect on improving patients’ hemodynamic parameters, with postoperative MAAD and LVEDd reduced compared to preoperative levels, while LVEF... read more
Implementing a Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy Team Reduces Length of Stay and Hospital Costs
Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more
Predictors of Weaning Failure in Ventilated ICU Patients
Predictors for weaning failure are widely researched. To date, 145 predictors have been investigated with varying intensity in 140 studies that are in line with the current weaning definition. It is no longer just individual... read more
Risk Factors for Secondary Organizing Pneumonia and Acute Fibrinous and Organizing Pneumonia in Patients with COVID-19 Pneumonia
Based on our findings, we observed that age ≥50 years, diabetes mellitus, and severe hypoxemia on admission (SpO2 ... read more
Extended Prone Position and 90-Day Mortality in Mechanically Ventilated Patients with COVID-19
Extended prone positioning (PP) was associated with improved 90-d survival in subjects with COVID-19 undergoing mechanical ventilation for severe ARDS. These findings suggest the potential benefit of EPP in the management... read more
Skin Decontamination to Prevent ICU Infections
Intensive care unit (ICU)-acquired infections can be serious complications of medical care of critically ill patients. Despite multiple tested and implemented preventive measures for such infections, their incidence is persistently... read more
Septic Shock in the Prehospital Setting
Septic shock (SS) is a potential life-threatening condition in which an early identification and immediate therapy stand out as the main cornerstones to improve survival chance; in this context, emergency medical services... read more
Protocolized Fluid Balance Neutralization During CRRT
Bitker et al. report the GO NEUTRAL randomized clinical trial results, which investigated fluid balance neutralization guided by functional hemodynamic monitoring (FHM) protocol versus a standard of care in critically ill... read more
Relationship between Concentrations of Oxygen and Levels of Oxidative Stress in Patients Receiving Oxygen Therapy for Severe COVID-19 Pneumonia
We evaluated the potential of high-flow oxygen therapy to increase oxidative stress and inflammation in COVID-19 patients. Our observation of decreased MDA levels when transitioning hypertensive patients from high-flow to... read more
Outcomes and inflammation changes in different types of immunocompromised patients with critically ill COVID-19 admitted to ICU
Critically ill COVID-19 patients admitted to the ICU exhibit distinct clinical outcomes based on their immunosuppression status, with cancer patients facing the highest mortality rate due to variations in inflammatory responses... read more