Tag: study
4m-gait speed test reliable/valid physical function measure in ARDS survivors
The 4-m gait speed is a reliable, valid, and responsive measure of physical function in acute respiratory distress syndrome survivors. The estimated minimal important difference will facilitate sample size calculations for... read more
Cellular Immunotherapy for Septic Shock
The infusion of freshly cultured allogenic bone marrow derived MSCs into participants with septic shock up to a dose of 3 million cells per kg (250 million cells) appears safe. Ages of participants in the interventional versus... read more
Cytomegalovirus infection in immunocompetent critically ill adults
Some studies have demonstrated an association between Cytomegalovirus (CMV) disease and increased mortality rates, prolonged intensive care unit and hospital length of stay, prolonged mechanical ventilation, and nosocomial... read more
Traditional vs. Extended Cefepime Infusion in Critically Ill Patients
Patients with Pseudomonas aeruginosa bacteremia or pneumonia had a reduced 28-day all-cause mortality and length of stay in the ICU when administered an extended infusion of cefepime.... read more
First Year in Care Critical to Retention, HIV Suppression
A previous study showed that the rate of long-term mortality more than doubled when patients missed visits in the first year after diagnosis.... read more
Anesthesia changes neuronal choreography
Even under deep anesthesia, nerve cells remain highly active. A study conducted by researchers from Charite - Universitätsmedizin Berlin has shown by high-resolution cellular imaging that local neuronal networks remain active... read more
Face Mask vs Helmet for Noninvasive Ventilation
In Reply Drs Taccone and Chiumello state that physicians must understand the helmet’s physiologic behavior in terms of CO2 rebreathing to ensure safety. Neurological impairment led to intubation in 5 of the 8 intubated... read more
Systematic review suggests synovial fluid analysis when necessary for diagnosis of gout
Gout presents with acute attacks of synovitis that start out as intermittent but can advance to chronic symptoms.... read more
Efficacy of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation
This study demonstrates that Shenfu injection in combination with conventional postresuscitation care bundle treatment is effective at improving clinical outcomes in patients with return of spontaneous circulation after in-hospital... read more
Hospital-Readmission Risk – Isolating Hospital Effects from Patient Effects
When the same patients were admitted with similar diagnoses to hospitals in the best-performing quartile as compared with the worst-performing quartile of hospital readmission performance, there was a significant difference... read more
Can Early Rehabilitation on the General Ward After an ICU Stay Reduce Hospital Length of Stay in Survivors of Critical Illness?
An early rehabilitation program in survivors of critical illness led to an earlier discharge from the hospital, improved functional recovery, and was also cost-effective and safe. In the per-protocol analysis, length of... read more
Hypertension and Prehypertension Underdiagnosed, Undertreated in U.S. Children
Hypertension and prehypertension in children often go undiagnosed, according to a new study published in Pediatrics. The study focused on children with abnormal blood pressures across the United States.... read more
The Ability of ICU Physicians to Estimate Long-Term Prognosis in Survivors of Critical Illness
Prognoses estimated by physicians incorrectly predicted long-term survival and HRQoL in one-third of ICU survivors. Moreover, inaccurate prognoses were generally the result of overoptimistic expectations of outcome. Among... read more
Conscious Sedation in TAVR Linked to Lower Mortality and Shorter Hospital Stays
The study, which captured approximately 90% of all patients who underwent TAVR in the United States during the study period, adds to a limited evidence base on the use of conscious sedation in this setting. Among those treated... read more
Association Between mRNA Expression of CD74 and IL10 and Risk of ICU-acquired Infections
Intensive care unit (ICU)-acquired infections (IAI) result in increased hospital and ICU stay, costs and mortality. To date, no biomarker has shown sufficient evidence and ease of application in clinical routine for the identification... read more
Patient Safety Collaborative Impact on Hospital-Acquired Harm
Improving patient safety often involves multifaceted interventions intended to change complex workflows. This prospective cohort study examined whether a collaborative improvement initiative across 33 pediatric hospitals... read more
The Overlaps of Asthma or COPD with OSA
Asthma, chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are the most common respiratory disorders worldwide. Given demographic and environmental changes, prevalence for each is likely to increase. Some... read more
Antibiotic Prescription Fill Rates Declining
Since 2010, antibiotic prescription rates in the U.S. have been declining among the commercially insured population, falling 9 percent during this period. In this report, the Blue Cross Blue Shield Association, in partnership... read more
Post-ICU Psychological Morbidity in Very Long ICU Stay Patients with ARDS and Delirium
Delirium was associated with memory impairment and PTSS-14 scores suggestive of PTSD, but not illness severity. 181 subjects were included. Illness severity did not correlate with delirium duration. On logistic regression,... read more
Biomarkers in AKI: That’s All the Story?
We would like to add to the recent editorial by McMahon on biomarkers of acute kidney injury (AKI), with a specific focus on biomarkers in the clinical setting of cardiac surgery-associated AKI (CSA-AKI). We agree with McMahon... read more
Cochrane Strategy to 2020
Strategy to 2020 aims to put Cochrane evidence at the heart of health decision-making all over the world. It defines how we intend to accomplish this and provides a framework for Cochrane's future decision-making, helping... read more
