Perceptions of Risk and Safety in the ICU

This study drew on cognitive research, specifically theories of cognitive dissonance, psychological safety, and situational awareness to explain how professionals' cognitive processes impacted on ICU behaviors. Our results... read more

Perceptions of Risk and Safety in the ICU

Rivaroxaban Lowers Cardiovascular Risk But Increases Bleeding Risk

In 27,395 patients with stable atherosclerotic disease, the addition of 2.5 mg rivaroxaban twice daily to aspirin therapy reduced the rates of cardiovascular death, stroke, or nonfatal MI, at the cost of increased major bleeding... read more

Rivaroxaban Lowers Cardiovascular Risk But Increases Bleeding Risk

Characteristics and Outcomes of ICU Survivors

A significant number of intensive care unit survivors evaluated 3 months after discharge had psychological, respiratory, motor, and socioeconomic problems; these findings highlight that strategies aimed to assist critically... read more

Characteristics and Outcomes of ICU Survivors

Quality Improvement Initiative to Reduce PICU Noise Pollution

Substantial noise pollution exists in our PICU, and utilizing the pediatric delirium bundle led to a significant noise reduction that can be perceived as half the loudness with hourly nighttime average dB meeting the EPA... read more

Quality Improvement Initiative to Reduce PICU Noise Pollution

New study finds stress levels skyrocket for family members of ICU patients

New research by Intermountain Healthcare finds family members of patients in ICU have anxiety, depression and post-traumatic stress lasting months. It's the first study of its kind to investigate the link between cortisol... read more

New study finds stress levels skyrocket for family members of ICU patients

Nutrition Therapy – One Size Does Not Fit All

A review paper published in Critical Care highlights the importance of employing targeted nutritional care for critically ill patients. The sad truth, according to the article, is that current ICU nutrition delivery worldwide... read more

Nutrition Therapy – One Size Does Not Fit All

Initial Crystalloid Resuscitation in Sepsis and Septic Shock

Ludwig Lin, MD, speaks with Daniel E. Leisman, BS, about the article, "Patterns and Outcomes Associated With Timeliness of Initial Crystalloid Resuscitation in a Prospective Sepsis and Septic Shock Cohort," published in Critical... read more

Machine Learning Model Predicts Sepsis in ICU Patients 12 Hours Before Diagnosis

A machine learning model accurately predicted the onset of sepsis in ICU patients four to 12 hours prior to clinical recognition in a recent study. The observational cohort study used data from more than 31,000 admissions... read more

Machine Learning Model Predicts Sepsis in ICU Patients 12 Hours Before Diagnosis

When Do Confounding by Indication and Inadequate Risk Adjustment Bias Critical Care Studies?

In critical care observational studies, when clinicians administer different treatments to sicker patients, any treatment comparisons will be confounded by differences in severity of illness between patients. We sought to... read more

Considerations for Physicians Using Ketamine for Sedation of Children in EDs

Ketamine use in emergency departments (EDs) for procedural sedation and analgesia is becoming increasingly common. However, few studies have examined patient factors related to adverse events associated with ketamine. This... read more

Considerations for Physicians Using Ketamine for Sedation of Children in EDs

The EM Educator Series: Sepsis in the ED

These posts provide brief mini-cases followed by key questions to consider while working. The featured questions provide important learning points for those working with you, as well as vital items to consider in the evaluation... read more

The EM Educator Series: Sepsis in the ED

Effect of a National Standard for Deteriorating Patients on Intensive Care Admissions Due to Cardiac Arrest in Australia

The main objective of this study is to assess whether a national standard for improving care of deteriorating patients affected ICU admissions following cardiac arrests from hospital wards. Introducing a national standard... read more

Effect of a National Standard for Deteriorating Patients on Intensive Care Admissions Due to Cardiac Arrest in Australia

Six-month Outcome of Immunocompromised Severe ARDS Patients Rescued by ECMO

Recently diagnosed immunodeficiency is associated with a much better prognosis in ECMO-treated severe ARDS. However, low 6-month survival of our large cohort of immunocompromised patients supports restricting ECMO to patients... read more

Six-month Outcome of Immunocompromised Severe ARDS Patients Rescued by ECMO

How Do You Feel? Subjective Perception of Recovery

Long-term subjective and objective outcome appears good in the majority of cardiac arrest survivors. Specific functional and cognitive impairments were found in patients reporting unsatisfactory recovery. Subjective recovery... read more

How Do You Feel? Subjective Perception of Recovery

Healthcare Utilization and Infection in the Week Prior to Sepsis Hospitalization

Over 45% of sepsis patients had clinician-based encounters in the week prior to hospitalization with an increasing frequency of diagnoses for acute infection and antibiotic use in the outpatient setting. These presepsis encounters... read more

Healthcare Utilization and Infection in the Week Prior to Sepsis Hospitalization

Central Venous Catheter – Which Needle?

A prospective randomised trial comparing insertion success rate and incidence of catheterisation-related complications for subclavian venous catheterisation using a thin-walled introducer needle or a catheter-over-needle... read more

Central Venous Catheter – Which Needle?

Serum Lactate Upon Emergency Department Arrival as Predictor of 30-day In-Hospital Mortality

Despite of numerous evidences that elevated serum lactate levels were associated with unfavorable outcomes, there have been no study demonstrated an optimal cutoff of serum lactate in unselected patients. This study was aimed... read more

Serum Lactate Upon Emergency Department Arrival as Predictor of 30-day In-Hospital Mortality

The Fallacy of Time-to-Intervention Studies

We are barraged by time-to-intervention studies (door-to-balloon time, time-to-antibiotics, door-to-needle, etc.). However, it must be kept in mind that these studies are purely correlational in design. Such studies cannot... read more

The Fallacy of Time-to-Intervention Studies