Manual vs. Integrated Automatic Load-distributing Band CPR with Equal Survival after out of Hospital Cardiac Arrest

Between March 5, 2009 and January 11, 2011 a randomized, unblinded, controlled group sequential trial of adult out-of-hospital cardiac arrests of presumed cardiac origin was conducted at three US and two European sites. After... read more

Big Data Detects Sepsis In Major Hospitals

Data analytics have found that large medical facilities have higher rates of death from sepsis than their smaller hospital counterparts. Researchers from Houston Methodist Hospital recently used Big Data analytics to learn... read more

Hemodialysis and Survival in Intubated Salicylate-Poisoned Patients

Salicylate-poisoned patients can be incredibly complex and severely ill. Secondary to the significant acid-base abnormalities that can accompany salicylate poisoning, hemodialysis (HD) is sometimes required to facilitate... read more

No Major Azithromycin Arrhythmia Risk in Huge European Cohort

Current use of azithromycin (Zithromax/Zmax, Pfizer) was linked with a twofold increased risk of ventricular arrhythmia compared with no antibiotic use, but this risk disappeared when azithromycin use was compared with amoxicillin... read more

Admission to the ICU is Associated With Changes in the Oral Mycobiome

A prospective exploratory study was conducted to characterize the oral mycobiome at baseline and determine whether changes occur after admission to the intensive care unit (ICU). We found that ICU admission is associated... read more

Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department

In this multicenter prospective cohort study involving 879 patients with suspected infection treated at the emergency department, the qSOFA was better at predicting in-hospital mortality with an area under the receiver operating... read more

The effect of day of the week on short- and long-term mortality for emergency general surgery

The effect of day of the week on outcome after surgery is the subject of debate. The aim was to determine whether day of the week of emergency general surgery alters short- and long-term mortality. Dr Mike Gillies and... read more

Effect of an automated notification system for deteriorating ward patients on clinical outcomes

We performed a prospective before-and-after study in all patients admitted to two clinical ward areas in a district general hospital in the UK. We examined the effect on clinical outcomes of deploying an electronic automated... read more

Mindfulness Program Aims to Help Nurses Better Manage Stress

Creating a nursing workforce that is resilient to occupational stress and burnout is critical for engagement, job satisfaction and retention, as well as the overall success of any healthcare organization. The overall goal... read more

Antipyretic Therapy in Critically Ill Septic Patients

This meta-analysis aimed to examine the impact of antipyretic therapy on mortality in critically ill septic adults. Inclusion criteria were observational or randomized studies of septic patients, evaluation of antipyretic... read more

Telemedicine and e-Health

Telemedicine-Assisted Intubation in Rural Emergency Departments: A National Emergency Airway Registry Study. Intubation in rural emergency departments (EDs) is a high-risk procedure, often with little or no specialty support.... read more

Many Factors Contribute to Nurses' Alarm Response Time

Multiple factors including nurses' experience and assignments determined how fast they responded when monitoring alarms were triggered in a children's hospital, a video analysis found. Nurses were more likely to... read more

Which position is safest for central line placement: subclavian, jugular, femoral?

Where to place a central venous catheter is a decision driven mainly by individual experience and preference. The limited evidence available has not established any site as superior; the subclavian position has been reported... read more

Komodo dragon-inspired synthetic peptide DRGN-1 promotes wound-healing of a mixed-biofilm infected wound

Cationic antimicrobial peptides are multifunctional molecules that have a high potential as therapeutic agents. We have identified a histone H1-derived peptide from the Komodo dragon (Varanus komodoensis), called VK25. Using... read more

Communicating Context in Quality Improvement Reports

The study by Demb and colleagues reports on the positive results of an intervention strategy to reduce excess radiation exposure across 5 academic medical centers associated with the University of California. Leading up to... read more

The impact of emergency department crowding on early interventions and mortality in patients with severe sepsis

Critically ill patients require significant time and care coordination in the emergency department (ED). We hypothesized that ED crowding would delay time to intravenous fluids and antibiotics, decrease utilization of protocolized... read more

Value-Based Reforms and the Hospital Readmission Reduction Program

In this longitudinal study of 2837 US hospitals between 2008 and 2015, we found that participation in 1 or more Medicare value-based reforms - including the Meaningful Use of Electronic Health Records program, the Accountable... read more

The Prevalence of Acute Critical Neurological Disease in Children

Neurologic insults are a significant pediatric international health issue. They are frequent and contribute substantial morbidity and mortality. These data suggest a need for an increased focus on acute critical neurologic... read more

The association of sleep quality, delirium, and sedation status with daily participation in physical therapy in the ICU

Poor sleep is common in the ICU setting and may represent a modifiable risk factor for patient participation in ICU-based physical therapy (PT) interventions. This study evaluates the association of perceived sleep quality,... read more

Association between delirium superimposed on dementia and mortality in hospitalized older adults

In a prospective cohort study, Thiago Junqueira Avelino-Silva and colleagues examine the association of delirium superimposed on dementia on hospital mortality and 12-month mortality in hospitalized older adults. This was... read more

Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old Type 2 Diabetic Patients

Type 2 diabetes (T2D) in elderly patients is associated with accelerated loss of skeletal muscle mass and strength. However, there are few meta-analysis reviews which investigate the effects of resistance training (RT) on... read more

A Call for Fresh Airway Management Standards

Anesthesiology News recently reported on a study that promoted the LMA in prone position to "avoid intubation, reduce use of relaxants and minimize airway trauma." This study reflects increasing confusion in a complex... read more