VA-ECMO in High-Risk Pulmonary Embolism

High-risk Pulmonary Embolism (PE) has an ominous prognosis and requires emergent reperfusion therapy, primarily systemic thrombolysis (ST). In deteriorating patients or with contraindications to ST, Veno-Arterial Extracorporeal... read more

VA-ECMO in High-Risk Pulmonary Embolism

Multiple Electrolytes Solution vs. Saline as Bolus Fluid for Pediatric Septic Shock Resuscitation

Among children presenting with septic shock, fluid resuscitation with MES (balanced crystalloid) as compared with 0.9% saline resulted in a significantly lower incidence of new and/or progressive AKI during the first 7 days... read more

Multiple Electrolytes Solution vs. Saline as Bolus Fluid for Pediatric Septic Shock Resuscitation

Acute Kidney Injury in ICU Patients

Patients admitted to the intensive care unit are prone to various complications, one of which is acute kidney injury (AKI). The etiology of acute kidney injury can be multifactorial. Among the various causes, sepsis remains... read more

Acute Kidney Injury in ICU Patients

Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Science is digging for the varied presentation of COVID-19 patients exposed to the same risk factors, and medical conditions may be influenced by the presence of polymorphic genetic variants. This study investigated the link... read more

Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Balloon therapy is an empirical example that patients with respiratory tract diseases can use to improve their daily care. The diaphragm and ribs are expanded and raised by the intercostal muscles, which are activated during... read more

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Oxygen Support Needs in Children with RSV vs. COVID-19

Children with respiratory syncytial virus (RSV) had a higher risk of pneumonia, bronchiolitis, and a hospital stay of more than 4 days vs children with COVID-19 or influenza. Investigators compared demographic and clinical... read more

Oxygen Support Needs in Children with RSV vs. COVID-19

Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients

Unmodified risk variables for nosocomial bloodstream infections (BSIs) included male sex and leukocytosis at admission. Using methylprednisolone and obtaining a cumulative dosage of dexamethasone were adjusted risk variables... read more

Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients

Choosing Wisely Interventions to Reduce Antibiotic Overuse

These real-world multicomponent interventions responding to physician pay-for-performance (P4P) incentives were associated with substantial reductions in antibiotic prescriptions for acute respiratory tract infections (ARTIs)... read more

Choosing Wisely Interventions to Reduce Antibiotic Overuse

Comparison of ETA and BALF mNGS in Severe Pneumonia

Our study showed that some differences in the microbiological diagnosis via endotracheal aspirate (ETA) mNGS and bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) appear to exist. Clinicians... read more

Comparison of ETA and BALF mNGS in Severe Pneumonia

Heparin-Binding Protein Predictive Value and D-Dimer in Sepsis Patients

As common clinical indicators for predicting sepsis, both HBP and D-dimer have high diagnostic effectiveness. Furthermore, the combined application of these two biomarkers can achieve favorable effects. In clinical practice,... read more

Heparin-Binding Protein Predictive Value and D-Dimer in Sepsis Patients

Albumin Infusion May Decrease the Mortality of Hypoalbuminemia Patients with Severe Acute Pancreatitis

Our study revealed that the lowest albumin level within 1 week after admission was independently associated with mortality in severe acute pancreatitis (SAP). In addition, infusing albumin may decrease mortality for hypoalbuminemia... read more

Albumin Infusion May Decrease the Mortality of Hypoalbuminemia Patients with Severe Acute Pancreatitis

CEUS Value in Diagnosis of AKI in ICU patients

Ultrasound can assess renal perfusion, but its role in the evaluation of acute kidney injury (AKI) is still unclear. This prospective cohort study was to investigate the value of contrast-enhanced ultrasound (CEUS) in the... read more

CEUS Value in Diagnosis of AKI in ICU patients

Dexmedetomidine Improved Sleep Quality in the ICU After Laryngectomy

This pilot study found that a 0.03 μg/kg/h dexmedetomidine infusion improved objective and subjective sleep quality in patients admitted to the ICU after laryngectomy. The dosing regimen used was safe and feasible for use... read more

Dexmedetomidine Improved Sleep Quality in the ICU After Laryngectomy

Immediate Norepinephrine vs. Initial Fluid Loading

In endotoxemic shock, immediate start of norepinephrine significantly improved regional splanchnic and intestinal microcirculatory flows when compared with mandatory fixed-dose fluid loading preceding norepinephrine. Immediate... read more

Immediate Norepinephrine vs. Initial Fluid Loading

High Speed Blood Flow Measurements Enabled by LW-iDCS

In this work we have demonstrated the development of long wavelength, interferometric diffuse correlation spectroscopy. Using a fiber optic probe with collocated detection fibers, we were able to directly compare measured... read more

High Speed Blood Flow Measurements Enabled by LW-iDCS

TEE Before Cardioversion in Atrial Fibrillation Patients

Transesophageal echocardiography (TEE) offers an invaluable, non-invasive avenue for diagnosing and managing various cardiac conditions, including atrial fibrillation (AF). As the most common cardiac arrhythmia, AF affects... read more

TEE Before Cardioversion in Atrial Fibrillation Patients

Secondary Bacterial Pneumonia is the Key Factor in COVID-19 Fatalities Not Cytokine Storm

A recent study found that secondary bacterial pneumonia, rather than the much-discussed “cytokine storm,” is a significant factor in COVID-19-related fatalities. Almost half of the patients who required mechanical... read more

Secondary Bacterial Pneumonia is the Key Factor in COVID-19 Fatalities Not Cytokine Storm

Iatrogenic Hypoxemia and Atrial Septal Defect Due to Electrical Storm Ablation After Left Ventricular Assist Device

Predominant strategies for the management of electrical storm include antiarrhythmic medical therapy, beta-blockers, and catheter ablation. Some studies have demonstrated refractory electrical storm managed with mechanical... read more

Iatrogenic Hypoxemia and Atrial Septal Defect Due to Electrical Storm Ablation After Left Ventricular Assist Device