Risks and Burdens of Incident Diabetes in Long COVID

Risks and Burdens of Incident Diabetes in Long COVID

In the post-acute phase, we report increased risks and 12-month burdens of incident diabetes and antihyperglycaemic use in people with COVID-19 compared with a contemporary control group of people who were enrolled during... read more

The Family in Preventing Delirium in the ICU

The Family in Preventing Delirium in the ICU

Extended visits, development of family-mediated activities, and redirection are non-pharmacological strategies that reduce the incidence of delirium in the ICU and offer multiple benefits to the patient and family/caregiver. The... read more

Casemix, management, and mortality of patients receiving emergency neurosurgery for TBI

Casemix, management, and mortality of patients receiving emergency neurosurgery for TBI

Patients receiving emergency neurosurgery for traumatic brain injury (TBI) differed considerably in their admission characteristics and management across human development settings. Level of human development was associated... read more

Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England

Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England

The risk of severe outcomes following SARS-CoV-2 infection is substantially lower for omicron than for delta, with higher reductions for more severe endpoints and significant variation with age. Underlying the observed risks... read more

Association Between Dexamethasone Treatment for COVID-19 Patients and Rates of Hospital Readmission and Mortality

Association Between Dexamethasone Treatment for COVID-19 Patients and Rates of Hospital Readmission and Mortality

Current guidelines recommend use of dexamethasone, 6 mg/d, up to 10 days or until discharge for patients hospitalized with COVID-19. Whether patients who received less than 10 days of corticosteroids during hospitalization... read more

Electronic Pneumonia Decision Support Helps Reduce Mortality by 38% in Community Hospitals

Electronic Pneumonia Decision Support Helps Reduce Mortality by 38% in Community Hospitals

Pneumonia was the leading cause of death from infectious diseases in the United States, even before the COVID-19 pandemic, and continues to be a leading cause of death. In the study, researchers at Intermountain Healthcare... read more

Sotrovimab Effect Among High-risk COVID-19 Patients

Sotrovimab Effect Among High-risk COVID-19 Patients

Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more

Percussion Pacing – An Almost Forgotten Procedure for Hemodynamically Unstable Bradycardias?

Percussion Pacing – An Almost Forgotten Procedure for Hemodynamically Unstable Bradycardias?

More than 80 years after its first description by Eduard Schott, percussion (fist) pacing remains a little known procedure even though it represents an instantly available and easy to perform treatment for temporary emergency... read more

Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema

Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema

This study compared the effect of placebo versus the bradykinin B2 receptor antagonist icatibant on symptoms of ACE inhibitor–associated angioedema in a mixed race population of patients. The study does not support the... read more

Therapeutic Hyperthermia Associated with Improved Survival in Afebrile Critically Ill Patients with Sepsis

Therapeutic Hyperthermia Associated with Improved Survival in Afebrile Critically Ill Patients with Sepsis

Participants randomized to external forced-air warming did not have a difference in HLA-DR expression or IFN-γ production. In this pilot study, however, 28-day mortality was lower in the intervention group. Future research... read more

Incidence of Delirium in ICU Inpatients After Cognitive Exercise Intervention

Incidence of Delirium in ICU Inpatients After Cognitive Exercise Intervention

In this study, the relevant RCTs on cognitive exercise in ICU inpatients with delirium were screened for systematic evaluation and meta-analysis, aiming to explore the impact of cognitive exercises and routine nursing on... read more

Staff Experiences Relating to Early Mobilisation of Mechanically Ventilated Patients in Intensive Care

Staff Experiences Relating to Early Mobilisation of Mechanically Ventilated Patients in Intensive Care

Early mobilisation of mechanically ventilated patients has been suggested to be effective in mitigating muscle weakness, yet it is not a common practice. Understanding staff experiences is crucial to gain insights into what... read more

Palliative Care Consultation and End-of-life Outcomes in Hospitalized COVID-19 Patients

Palliative Care Consultation and End-of-life Outcomes in Hospitalized COVID-19 Patients

Palliative care consultation was not associated with CPR performed at the end-of-life but was associated with increased incidence of comfort care being utilized. These results suggest that utilizing palliative care consultation... read more

The 1,3,5 Approach to Pediatric Cardiac Arrest

The 1,3,5 Approach to Pediatric Cardiac Arrest

While pediatric cardiac arrests are thankfully rare, their shock waves can seem incalculable. Several studies have outlined the mental health toll that these events can have on everyone involved. There is an appreciable... read more