The vaccine study you will never see

The vaccine study you will never see

I’ve seen a lot of social media posts or comment threads that say we don’t have any studies to prove that the CDC's vaccine schedule is safe or effective. I think they mean that we haven’t done the best study. As... read more

Enhanced Recovery After Surgery Program Implementation

Enhanced Recovery After Surgery Program Implementation

In this pre-post difference-in-differences study of 15 849 surgical patients at 20 medical centers in Northern California, implementation of a multifaceted enhanced recovery program was associated with a one-third reduction... read more

The Impact of Neonatal Simulations on Trainees Stress and Performance

The Impact of Neonatal Simulations on Trainees Stress and Performance

Neonatal simulations cause significant anticipatory and participatory stress. Despite this, trainees' performance score in simulation was over 80%. Simulated death did not impact performance, magnitude of rise in salivary... read more

Primary Stroke Center Protocol for Suspected Stroke by Large-Vessel Occlusion

Primary Stroke Center Protocol for Suspected Stroke by Large-Vessel Occlusion

In this cohort study, when the PSC protocol was fully executed, the rate of good outcomes was doubled and the time from arrival at the PSC to reperfusion at the CSC was almost 1 hour less than that with only a partial execution... read more

Obese Have Less Respiratory Insufficiency Than Nonobese During Endoscopy

Obese Have Less Respiratory Insufficiency Than Nonobese During Endoscopy

Obese patients showed less respiratory insufficiency (RI) than their nonobese counterparts during endoscopic surgery, according to a new study. The result was counterintuitive. Because of their higher rates of obstructive... read more

Reduction In Blood Gas Time To Result In ICU

Reduction In Blood Gas Time To Result In ICU

A recent time and motion study by University Hospital Southampton NHS Foundation Trust has demonstrated a 1.5 minute (>20%) reduction in time to blood gas results when using the Proxima bedside blood gas monitoring system... read more

PTSD, Psychotropic Medication Use, and the Risk of Dementia Among US Veterans

PTSD, Psychotropic Medication Use, and the Risk of Dementia Among US Veterans

Objective: To determine the associations between PTSD, psychotropic medication use, and the risk for dementia. PTSD diagnosis significantly increased the risk for dementia diagnosis (HR = 1.35; [95% CI = 1.27–1.43]). However,... read more

Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?

Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?

Acute kidney injury (AKI) is associated with increased morbidity and mortality. Although there are many causes of AKI, it is known that patients undergoing high-risk surgery are known to be at significant risk. Although much... read more

What Is Permitted in Text Messaging About Protected Health Information?

What Is Permitted in Text Messaging About Protected Health Information?

This Viewpoint discusses the best use of texting clinical information, noting that neither Health Insurance Portability and Accountability Act nor the Health Information Technology for Economic and Clinical Health Act offer... read more

Albumin Administration in Sepsis: The Case for and Against

Albumin Administration in Sepsis: The Case for and Against

Serum albumin is an essential plasma protein, with a variety of homeostatic and predictive roles in health and disease. Hypoalbuminaemia is common in critical illness. Human albumin solution has been administered clinically... read more

Physician Depression and Suicidality

Physician Depression and Suicidality

As physicians, we frequently care for patients with depression and suicidal ideations. On occasion, we may also have to treat patients who have actively attempted suicide via methods such as medication overdose or self-inflicted... read more

Both Positive and Negative Fluid Balance May Be Associated With Reduced Long-Term Survival in the Critically Ill

Both Positive and Negative Fluid Balance May Be Associated With Reduced Long-Term Survival in the Critically Ill

Among critically ill patients with acute kidney injury, exposure to positive fluid balance, compared with negative fluid balance, has been associated with mortality and impaired renal recovery. However, it is unclear whether... read more

Antimicrobial Stewardship and Appropriate Antimicrobial Prescribing in Hospitals

Antimicrobial Stewardship and Appropriate Antimicrobial Prescribing in Hospitals

This study examines whether an antimicrobial stewardship approach grounded in behavioral theory and focusing on preserving prescriber autonomy and participation is associated with appropriateness of antimicrobial prescribing... read more

New Ways for Research Findings to Reach More People

New Ways for Research Findings to Reach More People

When it comes to sharing new research findings with the world, Twitter has emerged as a key tool for scientists - and for the journals where they publish their findings. But a new study shows a way for that research to reach... read more

Implications of Prevalent Noncardiac Disease in the Cardiac ICU

Implications of Prevalent Noncardiac Disease in the Cardiac ICU

Half of >1000 patients of admitted to the cardiac intensive care unit (ICU) at a major tertiary-care center over about 1 year also had acute respiratory failure, acute kidney injury, or sepsis. Those with lung or kidney... read more

New Study: Economic Cost to Surviving ARDS

New Study: Economic Cost to Surviving ARDS

Research published today in the American Journal of Respiratory and Critical Care Medicine sheds light on the economic toll on survivors of acute respiratory distress syndrome. Nearly 50% of survivors who worked before they... read more

FDA Approves Label Changes for Pediatric General Anesthetic and Sedation Drugs

FDA Approves Label Changes for Pediatric General Anesthetic and Sedation Drugs

The FDA has approved labeling changes regarding the use of general anesthetic and sedation medicines in children younger than 3 years. General anesthetic and sedation drugs are necessary for patients, including young children... read more