Tag: study
Risk of Serious Blood Clots Up To 6 Months After COVID-19
A study from Sweden finds an increased risk of deep vein thrombosis (a blood clot in the leg) up to three months after COVID-19 infection, pulmonary embolism (a blood clot in the lung) up to six months, and a bleeding event... read more
Myopericarditis Following COVID-19 Vaccination and Non-COVID-19 Vaccination
The overall incidence of myopericarditis from 22 studies (405,272,721 vaccine doses) was 33·3 cases (95% CI 15·3–72·6) per million vaccine doses, and did not differ significantly between people who received COVID-19... read more
The impact of physical medicine and rehabilitation consultation on clinical outcomes in the SICU
The impact of a physical medicine and rehabilitation (PM&R) consultation on clinical outcomes in critically ill surgical patients remains unclear. The aim of this study is to examine whether the patients who received PM&R... read more
Physiological Responses to In-Bed Cycle Ergometry Treatment in ICU Patients with External Ventricular Drainage
These data suggest that supine CE in a heterogeneous cohort of neurocritical care patients with EVDs is safe and tolerable. Larger prospective studies are needed to determine the efficacy and optimal dose and timing of supine... read more
PPIs Should Not Be Prescribed for Upper GI Bleeds
The topic of PPIs for upper GI bleeds was one of the first posts on First10EM. There is no new evidence, and the bottom line is the same (just don’t use them), so if you are a long time reader, you can probably skip this... read more
Long-term Outcomes of Hospital Survivors Following an ICU Stay
Australian patients admitted to ICU who survive to discharge have worse long-term survival than the general population, except for the elderly admitted to ICU following cardiac surgery. These findings may assist during goal-of-care... read more
tPA for Critically Ill ICU Patients with COVID-19: Does Alteplase Help?
How do you define a last-ditch effort to save someone's life from COVID-19? Perhaps giving tPA to a severe COVID patient? At this point, I am certain many of us have attempted, with informed consent of course, therapies for... read more
General Anesthesia vs. Sedation Using Hemodynamic Control During Intraarterial Treatment for Stroke
The functional outcomes 3 months after endovascular treatment for stroke were similar with general anesthesia and sedation. Our results, therefore, suggest that clinicians can use either approach. Of 351 randomized patients,... read more
Music Therapy Intervention to Treat Sedation-Related Delirium in Critical Care
Sedation is an essential component of treatment for some patients admitted to the intensive care unit, but it carries a risk of sedation-related delirium. Sedation-related delirium is associated with higher mortality and... read more
Higher Dose Antibiotic Shown Safe in TB Patients Likely More Effective in Treating Deadliest Form of TB
A Johns Hopkins Children’s Center-led study in animals suggests that high doses of a widely used antibiotic called rifampin may safely treat and reduce the duration of treatment for the deadliest form of tuberculosis that... read more
Risks and Burdens of Incident Diabetes in Long COVID
In the post-acute phase, we report increased risks and 12-month burdens of incident diabetes and antihyperglycaemic use in people with COVID-19 compared with a contemporary control group of people who were enrolled during... read more
The Family in Preventing Delirium in the ICU
Extended visits, development of family-mediated activities, and redirection are non-pharmacological strategies that reduce the incidence of delirium in the ICU and offer multiple benefits to the patient and family/caregiver. The... read more
Casemix, management, and mortality of patients receiving emergency neurosurgery for TBI
Patients receiving emergency neurosurgery for traumatic brain injury (TBI) differed considerably in their admission characteristics and management across human development settings. Level of human development was associated... read more
Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England
The risk of severe outcomes following SARS-CoV-2 infection is substantially lower for omicron than for delta, with higher reductions for more severe endpoints and significant variation with age. Underlying the observed risks... read more
