Tag: study
Predicting Sudden Decrease in Oxygenation in Mechanically Ventilated ICU Patients as a Surrogate Marker for ARDS
Acute Respiratory Distress Syndrome (ARDS) is a life-threatening form of respiratory failure characterized by widespread lung inflammation that severely impairs oxygenation. Affecting millions of patients worldwide, ARDS... read more
Unlocking the Predictive Power of Nutritional Scores in Septic Patients
The study highlights the mNUTRIC score's practicality and reliability in assessing nutritional and inflammatory risks in septic patients, particularly in non-ICU settings. These findings suggest its potential utility... read more
Enteric Gram-negative Infections on Lung Transplant Clinical Outcomes
Lung transplant recipients (LTR) with more complicated post-operative courses were more likely to develop enteric gram-negative (GNR) infections which led to increased post-transplant morbidities. Pre-transplant GNR colonization... read more
Cumulative Fluid Balance During the First Three ICU Days in Septic Patients with Heart Failure
In septic patients with HFpEF, positive fluid balance of CFB-day1 might improve the prognosis of patients. However, from the second day, fluid overload was associated with poor prognosis. Therefore, we propose that on... read more
AKI and Mortality Predictors of Systemic Autoimmune Diseases and COVID-19
The present study highlights renal parameters and outcomes associated with various systemic autoimmune diseases and COVID-19. Patients who presented with low oxygen saturation (... read more
Prescribing Patterns and Effectiveness of Ceftolozane/Tazobactam in Immunosuppressed Patients
Treatment with Ceftolozane/Tazobactam (C/T) resulted in a high rate of clinical success in this real-world cohort of immunosuppressed patients, despite dosing that frequently deviated from labelled dosing. Pseudomonas... read more
Multi-dimensional Outcomes Following ECPR
Recent trials suggested that extracorporeal cardio-pulmonary resuscitation (ECPR) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or "ECMELLA" (VA-ECMO plus Impella) may improve short-term survival and neurological... read more
VEGFR1 Genetic Regulation During Sepsis and Association with ARDS Susceptibility
We identified biologically relevant protein quantitative trait loci (pQTLs) of vascular endothelial growth factor receptor 1 (VEGFR1) levels during sepsis in TCF20 and identified CYP2D6 as the gene more biologically implicated.... read more
Bundling Procedures in Critically Ill Trauma Patients and ICU LOS
Intubated trauma patients who presented with certain mechanisms (gunshot wounds (GSW), pedestrian struck), received blood transfusions, or exhibited severe/profound ISS may be more likely to receive immediate bundled lines... read more
APRV vs. BIPAP Ventilation in COVID-19 Associated ARDS
Despite of higher mean tidal volumes and higher mean airway pressures in airway pressure release ventilation (APRV) vs. biphasic positive airway pressure (BIPAP), both modes did not present an increased risk of volu- or barotrauma... read more
Cytokeratin-18 Levels in COVID-19 Patients
This study analyzed 176 samples, including 63 ICU-admitted patients and 88 non-ICU-admitted patients. A substantial difference was found between the AST and CK-18 levels of the patients receiving ICU care and those who did... read more
Ventilator Associated Pneumonia in ICU: Identification, Evaluation and Prevention
This study highlights the significant prevalence of Pseudomonas aeruginosa (PA) as a major bacterial pathogen causing ventilator-associated pneumonia (VAP) in ICU patients, with a high detection rate of 71.7% in tested patients,... read more
New Insights: Mortality in Nosocomial Lower Respiratory Tract Infections
This multicenter, multinational study conducted in Europe and Latin America sheds light on the clinical landscape of nLRTI, which continues to be an essential issue in the context of critical care. We provide insights... read more
ICU-AW in Cardiogenic Shock Patients Requiring Mechanical Circulatory Support
This study provides insights into the characteristics of intensive care unit-acquired weakness (ICU-AW) in patients with Cardiogenic Shock (CS) requiring mechanical circulatory support (MCS). ICU-AW frequently occurred... read more
New Insights: Inhaled Nitric Oxide in Severe COVID-19 Patients
This study provides novel insights into the use of inhaled nitric oxide in severe ARDS COVID-19 patients. Specifically, we demonstrate that the iNO effect of oxygenation improvement is delayed with a prolonged feature that... read more
Cellular Therapy with Mesenchymal Stromal Cells in Sepsis
Cellular therapy with mesenchymal stromal cells (MSCs) is a promising therapeutic modality in sepsis. Positive effects are mainly associated with frequent infusions and the dose of 1 × 106 cell/kg. Larger scale studies... read more
Association Between Early Ondansetron Use and Sepsis Risk in ICU Patients
In both patients with SOFA 3, early ondansetron use was correlated with a reduced risk of sepsis. Patients with early ondansetron use had lower odds of experiencing sepsis than patients without early ondansetron use, which... read more
Rhabdomyolysis Due to Nutritional Supplements Intake
habdomyolysis is a condition characterized by the destruction of muscle cells and subsequent release of it's intracellular contents. It is typically asymptomatic, with moderate creatine kinase elevation. Severe cases... read more
Single Lumen vs. Double Lumen Endotracheal Tube For Postoperative Swallowing Function in Lung Transplantation Patients
BackgroundThis study was conducted to investigate the effect of endotracheal tube type on post operative dysphagia in patients undergoing lung transplant surgery. Will patients who are intubated with a single lumen endotracheal... read more
Prognostic Value of Composite Inflammatory Markers in COPD Patients
Elevated systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), pan-immune inflammation value (PIV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are associated... read more
Approach to Peripheral Neuropathy
Peripheral neuropathy is frequently encountered in the clinical setting by doctors of various specialties. Neuropathies can be approached based on the temporal profile, spatial pattern and pathology. There is a need for... read more