10 Scientific Reasons in Support of Airborne SARS-CoV-2 Transmission

10 Scientific Reasons in Support of Airborne SARS-CoV-2 Transmission

Heneghan and colleagues' systematic review, funded by WHO, published in March, 2021, as a preprint, states: "The lack of recoverable viral culture samples of SARS-CoV-2 prevents firm conclusions to be drawn about airborne... read more

Optimal Needle Position for Decompression of Tension Pneumothorax

Optimal Needle Position for Decompression of Tension Pneumothorax

Tension Pneumothorax (TP) can occur as a potentially life-threatening complication of chest trauma. With the risk of respiratory and cardiac arrest, an immediate temporizing intervention for this condition is required by... read more

90 Day Outcomes of COVID-19 Patients in European ICUs

90 Day Outcomes of COVID-19 Patients in European ICUs

This communication delineates outcomes in COVID-19 patients in the context of ARDS severity, ventilatory management, and variables associated with mortality on a 90-day follow-up for subgroups of patients after ICU admission.... read more

Effect of Infusion Set Replacement Intervals on Catheter-related Bloodstream Infections

Effect of Infusion Set Replacement Intervals on Catheter-related Bloodstream Infections

The optimal duration of infusion set use to prevent life-threatening catheter-related bloodstream infection (CRBSI) is unclear. We aimed to compare the effectiveness and costs of 7-day (intervention) versus 4-day (control)... read more

Co-infection in Critically Ill Patients with COVID-19

Co-infection in Critically Ill Patients with COVID-19

During previous viral pandemics, reported co-infection rates and implicated pathogens have varied. In the 1918 influenza pandemic, a large proportion of severe illness and death was complicated by bacterial co-infection,... read more

Patient’s Clinical Presentation and CPPopt Availability: Any Association?

Patient’s Clinical Presentation and CPPopt Availability: Any Association?

In this retrospective multicenter study, none of the selected admission and treatment variables were related to the CPPopt yield. The median CPPopt yield was 80.7% (interquartile range 70.9–87.4%). None of the selected... read more

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more

Outcomes of Patients with COVID-19 and Relationship with Lung Ultrasound Signs

Outcomes of Patients with COVID-19 and Relationship with Lung Ultrasound Signs

In patients with COVID-19 pneumonia, Lung Ultrasound Signs (LUS) signs, including the aeration score, were related to respiratory and systemic symptoms 1 month after ultrasound screening examination. In these patients, a... read more

Use of Biomarkers to Identify AKI to Help Detect Sepsis in Patients with Infection

Use of Biomarkers to Identify AKI to Help Detect Sepsis in Patients with Infection

Use of the urinary (tissue inhibitor of metalloproteinases-2) × (insulin-like growth factor binding protein 7) test could identify acute kidney injury in patients with infection, possibly helping to detect sepsis, nearly... read more

Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments

Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments

In this study, a quality improvement intervention that trained physicians to communicate and plan ICU care with family members of critically ill patients in the ICU using TLTs was associated with improved quality of family... read more

Relationship Between Skeletal Muscle Area and Density and Clinical Outcome in Adults Receiving VV-ECMO

Relationship Between Skeletal Muscle Area and Density and Clinical Outcome in Adults Receiving VV-ECMO

Low skeletal muscle index at the commencement of venovenous extracorporeal membrane oxygenation (VV-ECMO) was associated with a longer duration of venovenous extracorporeal membrane oxygenation, whereas preserved skeletal... read more

A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia

A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia

The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and... read more

Clinical Features and Predictors in Critically Ill COVID-19 Patients

Clinical Features and Predictors in Critically Ill COVID-19 Patients

We aim to describe a case series of critically and non-critically ill COVID-19 patients in Singapore. This was a multicentered prospective study with clinical and laboratory details. Details for fifty uncomplicated COVID-19... read more

Role of N-Acetylcysteine in Non-acetaminophen-related Acute Liver Failure

Role of N-Acetylcysteine in Non-acetaminophen-related Acute Liver Failure

N-acetylcysteine (NAC) is well known to emergency medicine physicians as the antidote in acute acetaminophen ingestion. The scope of use for this medication beyond that is often not considered, such as in other etiologies... read more