Tag: study
Prevalence of Hepatopancreatic Injury in Patients with COVID-19
COVID-19 can cause liver injury. Mortality, disease severity, and hospital length of stay are increased in COVID-19 patients with hepatopancreatic injury. Forty-five thousand three hundred sixty patients were included... read more
COVID-19 and Myocardial Infarction
COVID-19 is a risk factor for myocardial infarction and stroke through self-controlled case series evaluation, a method that has been used to establish the risk of myocardial infarction associated with influenza infection. Regarding... read more
Oxygenation Responses Mechanisms to Proning and Recruitment in COVID-19 Pneumonia
In unresolving COVID-19 pneumonia, the respiratory mechanics and the gas-exchange response to prone positioning and recruitment largely depend on the following two factors: perfusion dysregulation and the amount of consolidated... read more
The Pulmonary Artery Catheter: A Solution Still Looking For a Problem
In 1970, Jeremy Swan, William Ganz, and colleagues published their seminal paper “Catheterization of the heart in man with use of flow-directed balloon-tipped catheter”. Few devices in our specialty have generated more... read more
Serum Sodium and In-Hospital Mortality in Critically Ill Patients
In this large multicenter observational cohort study of ICU patients, we aimed to assess the independent association of changes in serum sodium in the first 48 hours of ICU admission with in-hospital mortality for patients... read more
Aspirin is Linked with Increased Risk of Heart Failure
Aspirin use is associated with a 26% raised risk of heart failure in people with at least one predisposing factor for the condition. That’s the finding of a study published today in ESC Heart Failure, a journal of the European... read more
No Extra Risk For Transferring ECMO COVID-19 Patients
Previous experience has shown that transporting patients on extracorporeal membrane oxygenation (ECMO) is a safe and effective mode of transferring critically ill patients requiring maximum mechanical ventilator support to... read more
Impact of Mobilization on Vital Signs and Oxygen Saturation in Open-Heart Surgery
Early and frequent mobilization did not cause vital signs and oxygen saturation to deviate from normal limits in open-heart surgery patients. The difference between pulse and systolic blood pressure values measured before... read more
Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant
Among patients undergoing LT, use of iEPO was associated with similar risks for PGD-3 development and other postoperative outcomes compared with the use of iNO. A total of 201 randomized patients met eligibility criteria... read more
Weaning Methods From Mechanical Ventilation in Adult Patients
In general consideration, our study provided evidence that weaning with proportional assist ventilation has a high probability of being the most effective ventilation mode for patients with mechanical ventilation regarding... read more
Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors
This qualitative, multicenter, international study of caregivers of critical illness survivors identified consistently unmet needs, means by which caregivers accessed support post ICU, and several care mechanisms identified... read more
Ivermectin Not the Crisis It’s Claimed to Be
I can't remember any time when the U.S. Food and Drug Administration had to resort to the faux-folksy mode of expression to try to get its point across. We live in strange times. The FDA was responding, of course, to the... read more
SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role... read more
Critical Illness in Patients with Hematologic Malignancy
Critical illness in patients with a newly diagnosed hematologic malignancy is frequent, occurring early after diagnosis. Certain baseline characteristics can help identify those patients at the highest risk. A total of... read more
EDS: Early or Late in the Diagnostic Process?
Electronic differential diagnostic support (EDS) increased the number of diagnostic hypotheses and the likelihood of the correct diagnosis appearing in the differential, and these effects persisted irrespective of whether... read more
Mechanically Ventilated COVID-19 Patients: Long-term Survival Study
The long-term survival of mechanically ventilated patients with severe COVID-19 reaches more than 50% and may help to provide individualized risk stratification and potential treatments. 868 patients were included (median... read more
Hospitals With and Without Neurosurgery: Evaluating TBI Patients Outcomes
In our study, centralization of TBI patients significantly impacted short- and long-term outcomes. For TBI patients admitted to no-NSH centers, our results suggest that the least critically ill can effectively be managed... read more
Effect of Statins on Cognitive Outcome After TBI
Traumatic brain injury (TBI), also known as the "Silent Epidemic," is a growing devastating global health problem estimated to affect millions of individuals yearly worldwide with little public recognition, leading to many... read more
Can Early Cytokine Profile Discriminate Between GPB and GNB?
Sepsis is a principal cause of death in critical care units worldwide and consumes considerable healthcare resources. The aim of our study was to determine whether the early cytokine profile can discriminate between Gram-positive... read more
Difference in Sepsis Patients Outcomes Between First and Second-Hit Infections
Our study identifies a fundamental difference in patient outcomes between first-hit and second-hit bacterial infections, which may be due to genetic, microbiological, immunological, and environmental factors. This finding... read more
HIV and COVID-19 Increased Risk of Severe Outcomes
People living with HIV with detectable HIV viraemia, chronic comorbidities, and some subpopulations could be at increased risk of severe outcomes from COVID-19. These groups should be prioritised in clinical management and... read more
Impact of Tight Glucose Control on Circulating 3-hydroxybutyrate in Critically Ill Patients
Tight versus liberal glucose control in the context of early parenteral nutrition did not affect 3-hydroxybutyrate concentrations in critically ill patients. Hence, the protective effects of tight glucose control in this... read more
