Tag: study
COVID-19: a boost for intensive care authorship?
Almost 180 million cases of COVID-19 have been diagnosed, with almost 4.000.000 deaths. Since this pandemic had unprecedented worldwide healthcare and socio-economic effects, the scientific world is under exceptional pressure... read more
Severe Neonatal Hypernatremia
Neonatal hypernatraemia at this level, in this population, is strongly associated with weight loss. It occurs almost exclusively after attempts to initiate breast feeding, occurs uncommonly and does not appear to be associated... read more
Multi-task Prediction of Organ Dysfunction in ICUs
The intensive care unit (ICU) of a hospital looks after the most medically vulnerable patients, many of whom require organ support, such as mechanical ventilation or dialysis. While always critical, the demand on ICU services... read more
COVID-19 Restructures the Host Chromatin Architecture
SARS-CoV-2 has made >190-million infections worldwide, thus it is pivotal to understand the viral impacts on host cells. Many viruses can significantly alter host chromatin, but such roles of SARS-CoV-2 are largely unknown.... read more
Effects of Early Mobilization on the Prognosis of Critically Ill Patients
Early mobilization was effective in enhancing the recovery of critically ill patients, but more large-scale, multicenter randomized controlled trials are required to further confirm these findings. A total of 39 articles... read more
Personalized Mechanical Ventilation in ARDS
A personalized mechanical ventilation approach for patients with adult respiratory distress syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging, and biological phenotypes may improve ventilation... read more
Neuropsychiatric Disorders and COVID-19
We read with interest the Article by Maxime Taquet and colleagues1 in The Lancet Psychiatry that evaluated a large population (n=236 379) for neurological and psychiatric complications of COVID-19 via analysis of diagnostic... read more
The Gut in COVID‑19
In the last year, a growing number of articles addressed coronavirus disease 2019 (COVID-19), including its link with gastrointestinal (GI) (dys)function. We here highlight the most important findings regarding the role of... read more
Transcatheter arterial embolization for severe blunt liver injury in hemodynamically unstable patients
Transcatheter arterial embolization (TAE) in hemodynamically unstable patients who responded to initial infusion therapy to some extent has acceptable in-hospital mortality and clinical failure rates. Hemodynamic instability... read more
Prone Positioning and Survival in Mechanically Ventilated Patients with COVID-19
In-hospital mortality was lower in mechanically ventilated hypoxemic patients with coronavirus disease 2019 treated with early proning compared with patients whose treatment did not include early proning. Among 2,338 eligible... read more
Liver Dysfunction and COVID-19 Infection
Severe acute respiratory syndrome coronavirus 2 infection is the cause of coronavirus disease 2019 (COVID-19), which predominantly affects the respiratory system; it also causes systemic and multi-organic disease. Liver... read more
Psychological burden in patients with COVID-19 and their relatives 90 days after hospitalization
COVID-19 is linked to clinically relevant psychological distress in a subgroup of patients and their relatives 90 days after hospitalization. If confirmed in an independent and larger patient cohort, knowledge about these... read more
Moderna Vaccine 94.1% Efficacy Preventing Symptomatic COVID-19
The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants... read more
COVID-19 Surges Increased Patient Mortality
A recent study by scientists at the National Institutes of Health suggests that one in every four COVID-19 deaths in the United States may be attributed to hospitals strained by surging caseloads. Published in the Annals... read more
Reduced Sensitivity of COVID-19 Variant Delta to Antibody Neutralization
The SARS-CoV-2 B.1.617 lineage was identified in October 2020 in India1–5. It has since then become dominant in some indian regions and UK and further spread to many countries6. The lineage includes three main subtypes... read more
New Device for Intubation Through a Laryngeal Mask Airway
On review of the literature, it is abundantly obvious that an endotracheal tube (ETT) with a posterior-facing bevel and curved or tapered tip to center the tube on the scope and reduce hang-up is ideal for intubation over... read more
Is Daily Enoxaparin Dosing As Good As Twice Daily?
Venous thromboembolism (VTE) remains a big problem for trauma professionals and the patients they take care of. Every trauma center has some sort of VTE prophylaxis protocol for stratifying risk, prescribing mechanical... read more
Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations
In uncontrolled, moderate-to-severe asthma, higher baseline FeNO levels were associated with greater risk of severe asthma exacerbations, particularly in combination with elevated eosinophil count and prior exacerbations,... read more
Melatonin for Delirium Prevention in Hospitalized Patients
Melatonin/ramelteon are associated with reduction in delirium incidence in hospitalized patients. However, this effect seems confined to surgical and ICU patients. The optimum dosage and formulation of melatonin, and... read more
Preoperative vena cava filter placement in recurrent cerebral fat embolism following traumatic multiple fractures
Despite scarce evidence, we reckon that Inferior Vena Cava Filter (IVCF) could improve prognosis in selected patients with fat embolism syndrome (FES), especially those presenting high risk factors, after accurately weighing... read more
REGN monoclonal antibodies work in selected hospitalised COVID-19 patients
New findings suggest a significant benefit from REGN in terms of the primary outcome of mortality for patients who have low levels of their own antibodies at the time of admission. This was an unexpected result for me... read more
Multimorbidity on Long-Term Outcomes Following ICU Discharge
This national cohort study has demonstrated increased resource use for critical care survivors in the year following discharge but fails to replicate past findings of increased longer-term mortality. Multimorbidity, lifestyle... read more
