Some Signs of Recovery From Severe COVID-19 Lung Damage

In two early studies, researchers said some patients showed signs of healing just weeks after leaving the hospital. Lingering shortness of breath and diminished stamina have dogged many COVID patients whose lungs were... read more

Some Signs of Recovery From Severe COVID-19 Lung Damage

Detecting Patient Deterioration Using Artificial Intelligence in a Rapid Response System

The developed artificial intelligence based on deep-learning, deep learning-based early warning system, accurately predicted deterioration of patients in a general ward and outperformed conventional methods. This study... read more

Detecting Patient Deterioration Using Artificial Intelligence in a Rapid Response System

Data Visualization of Recent Sepsis Studies

Medicare is the US federal health insurance program for people who are 65 or older, certain younger people with disabilities, and people with End-Stage Renal Disease. Medicare spending in 2018 was 21% of the national US total... read more

Data Visualization of Recent Sepsis Studies

Viscoelastic Hemostatic Assay Augmented Protocols for Major Trauma Hemorrhage

Our international randomized trial has evaluated the role of VHAs to individualize care and augment empiric hemostatic resuscitation in the challenging and time-critical environment of trauma care. Empiric haemostatic therapy... read more

The Effectiveness of 8 Nonpharmaceutical Interventions Against COVID-19 in 41 Countries

Governments are attempting to control the COVID-19 pandemic with nonpharmaceutical interventions (NPIs). However, it is still largely unknown how effective different NPIs are at reducing transmission. Data-driven studies... read more

The Effectiveness of 8 Nonpharmaceutical Interventions Against COVID-19 in 41 Countries

Outcomes of Neonates Born to Mothers With Severe COVID-19

In this cohort study, no evidence of vertical transmission of SARS-CoV-2 was identified in the first 101 newborns born to mothers positive for or with suspected SARS-CoV-2 infections at a large medical center in an epicenter... read more

Outcomes of Neonates Born to Mothers With Severe COVID-19

Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy

To the best of our knowledge, this is the first multicenter study that prospectively evaluated the benefits and the role of HFNO combined with awake prone positioning in the prevention of intubation in an adjusted large cohort... read more

Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy

Using Dynamic Variables to Guide Perioperative Fluid Management

Intravenous fluid administration is an integral part of patient management during anesthesia. This practice has a strong clinical rationale since a decrease in blood volume, either present before or developing during surgery,... read more

Using Dynamic Variables to Guide Perioperative Fluid Management

TEG for Hypocoagulable Patients with Non-Traumatic Bleeding

Thromboelastogram (TEG) has been extensively studied in trauma and surgical patients, but has not been well studied in nontraumatic bleeding, nor has its use been well evaluated in the emergency department. This study... read more

TEG for Hypocoagulable Patients with Non-Traumatic Bleeding

Efficacy and Safety of a Paired Sedation and Ventilator Weaning

The purpose of this study is to determine the impact of a new RN/RRT (Registered Nurse/Registered Respiratory Therapist) directed 2-step protocol to wean patients off of a ventilator. This protocol involves daily attempts... read more

Efficacy and Safety of a Paired Sedation and Ventilator Weaning

Endothelial Dysfunction Role During COVID-19

Emerging data suggest a crucial role of endothelial dysfunction during SARS-CoV-2 infection, as a direct target of the virus and inflammatory cytokines as well as the main actor in orchestrating a pro-inflammatory and pro-coagulant... read more

Endothelial Dysfunction Role During COVID-19

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19

This study found a higher rate of gastrointestinal complications, including mesenteric ischemia, in critically ill patients with COVID-19 compared with propensity score–matched patients without COVID-19, suggesting a distinct... read more

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19

Early Arterial Embolization and Mortality in Mechanically Ventilated Patients With Hemoptysis

The objective of this study was to clarify whether early intervention by arterial embolization reduced mortality in mechanically ventilated patients with hemoptysis. The results show that early intervention by arterial... read more

Early Arterial Embolization and Mortality in Mechanically Ventilated Patients With Hemoptysis

Pre-hospital Care & Interfacility Transport of 385 COVID-19 Emergency Patients

All participating air ambulance providers were prepared for COVID-19. Safe care and transport of suspected or confirmed COVID-19 patients is achievable. Most patients on primary missions were transported by ground. These... read more

Pre-hospital Care & Interfacility Transport of 385 COVID-19 Emergency Patients

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19

No benefit of hydroxychloroquine or chloroquine on the survival of COVID-19 patients found. For hydroxychloroquine, the confidence interval is compatible with increased mortality or negligibly reduced mortality. Findings... read more

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19

Risk of Death More Than Doubled in People with Both Flu and COVID-19

People infected with both flu and SARS-CoV-2 are more than twice as likely to die as someone with the new coronavirus alone, emerging evidence from England has shown. An analysis by Public Health England (PHE) of cases... read more

Risk of Death More Than Doubled in People with Both Flu and COVID-19

Fibrin-derived Peptide as Salvage Treatment in Critically Ill Patients with COVID-19-associated ARDS

After SARS-CoV-2 first occurred in China in December of 2019, it set out to become a global pandemic. Critically ill patients constitute about 2–9% of all infected patients and progress from pneumonia and hypoxemia to multi-organ... read more

Fibrin-derived Peptide as Salvage Treatment in Critically Ill Patients with COVID-19-associated ARDS

Management of Post-acute COVID-19 in Primary Care

Post-acute COVID-19 ("long covid") seems to be a multisystem disease, sometimes occurring after a relatively mild acute illness. Clinical management requires a whole-patient perspective. This article, intended for... read more

Management of Post-acute COVID-19 in Primary Care