VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a high mortality. This study assessed venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for sepsis-induced cardiogenic shock refractory... read more

VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

Thrombotic and Hemorrhagic Complications in Critically Ill Patients with COVID-19

Critically ill patients with COVID-19 experience high rates of venous and arterial thrombotic complications. The rates of bleeding may be higher than previously reported and re-iterate the need for randomised trials to better... read more

Thrombotic and Hemorrhagic Complications in Critically Ill Patients with COVID-19

The Pooled Prevalence of Pulmonary Embolism in Patients with COVID-19

It is needed to pay more attention to the relatively high prevalence of pulmonary embolism (PE) in COVID-19 patients, especially in ICU wards. Future studies that will explore the detection method considering high infectivity... read more

The Pooled Prevalence of Pulmonary Embolism in Patients with COVID-19

Outcomes of COVID-19 Patients Admitted to Australian ICUs During Early Pandemic Phase

During the early phase of the pandemic in Australia, patients admitted to ICU with COVID-19 had lower mortality and longer length of stay than reported from other regions. These findings reinforce the importance of ensuring... read more

Outcomes of COVID-19 Patients Admitted to Australian ICUs During Early Pandemic Phase

Real-time AI prediction for major adverse cardiac events in emergency department patients with chest pain

An artificial intelligence (AI) real-time prediction model is a promising method for assisting physicians in predicting major adverse cardiac events (MACE) in ED patients with chest pain. Further studies to evaluate the impact... read more

Real-time AI prediction for major adverse cardiac events in emergency department patients with chest pain

Angiotensin II in Post Cardiopulmonary Bypass Vasoplegia

Post cardiopulmonary bypass vasoplegia is common, and associated with poor outcomes. Traditional management strategies involving escalating doses of catecholamines, vasopressin and adjuncts such as methylene blue and hydroxycobalamin... read more

Angiotensin II in Post Cardiopulmonary Bypass Vasoplegia

Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children

In this cohort study of 315 children with COVID-19 and 1402 children with seasonal influenza, there were no statistically significant differences in the rates of hospitalization, admission to the intensive care unit, and... read more

Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children

Quality of Life of Intensive Care Unit-Acquired Weakness Symptoms in Long-Term Intensive Care Survivors

Intensive care unit-acquired weakness (ICUAW) symptoms were disturbingly common in the majority of long-term survivors, indicating that symptoms persist up to 10y and frequently impair QoL. However, only a small number of... read more

Quality of Life of Intensive Care Unit-Acquired Weakness Symptoms in Long-Term Intensive Care Survivors

Sepsis and the Obesity Paradox: Size Matters in More Than One Way

Our retrospective analysis suggests that although patient size (i.e., body mass index) is a predictor of in-hospital death among all-comers with sepsis—providing further evidence to the obesity paradox—it adds that illness... read more

Sepsis and the Obesity Paradox: Size Matters in More Than One Way

Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs

Nasotracheal intubation is used in a minority of U.S. PICUs and mainly among young cardiac patients. Nasotracheal intubation is associated with a lower rate of unplanned extubations in this patient population. Future... read more

Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs

From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response

Between June 18 and Aug 3, 2020, Ministry of Health of the Russian Federation enrolled 76 participants to the two studies (38 in each study). In each study, 9 volunteers received rAd26-S in Phase 1, nine received rAd5-S in... read more

From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response

Hydroxychloroquine With or Without Azithromycin

Among patients hospitalized with mild-to-moderate COVID-19, the use of hydroxychloroquine, alone or with azithromycin, did not improve clinical status at 15 days as compared with standard care. A total of 667 patients... read more

Hydroxychloroquine With or Without Azithromycin

Effects of Telemedicine ICU Intervention on Care Standardization and Patient Outcomes

In this pre-post observational study, telemedicine ICU intervention was associated with improvements in care standardization and decreases in ICU and hospital mortality and length of stay. The mortality benefits were mediated... read more

Effects of Telemedicine ICU Intervention on Care Standardization and Patient Outcomes

Asthma Among Hospitalized Patients with COVID-19 and Related Outcomes

Among hospitalized patients 65 years or younger with severe COVID-19, asthma diagnosis was not associated with worse outcomes, regardless of age, obesity, or other high-risk comorbidities. Future population-based studies... read more

Asthma Among Hospitalized Patients with COVID-19 and Related Outcomes

Evaluation of SARS-CoV-2 Serology Assays Reveals a Range of Test Performance

Appropriate use and interpretation of serological tests for assessments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and potential immunity require accurate data on assay performance.... read more

Evaluation of SARS-CoV-2 Serology Assays Reveals a Range of Test Performance

Artificial Neural Networks Improve Prediction and Risk Classification in ICU Patients

A supervised machine learning model using artificial neural networks (ANN) predicted neurological recovery, including survival excellently, and outperformed a conventional model based on logistic regression. Among the data... read more

Artificial Neural Networks Improve Prediction and Risk Classification in ICU Patients

EPSS vs. Fractional Shortening for LV Function – Is EPSS Good Enough?

In a recent issue of the Journal of Ultrasound through AIUM, Weekes et al. (and Kendall et al in AM J EM) talk about a hot topic that emergency and critical care physicians hold dear to them – the EPSS , or E-point septal... read more

EPSS vs. Fractional Shortening for LV Function – Is EPSS Good Enough?

Variation in Hospital Visitor & ICU Communication Policies Due to COVID-19

A new study documents how 49 of those hospitals reacted, and how those efforts varied. It finds that virtually all hospitals put in place a "no visitors" blanket policy. But 59% of hospitals did allow some exceptions to this... read more

Variation in Hospital Visitor & ICU Communication Policies Due to COVID-19