Intracranial Pressure & Neuromonitoring XVI

This book introduces the latest advances relating to the pathophysiology, biophysics, monitoring and treatment of traumatic brain injury, hydrocephalus, and stroke presented at the 16th International Conference on Intracranial... read more

Intracranial Pressure & Neuromonitoring XVI

Fixing Hypernatremia: Acting Fast or Acting Slow?

This is the largest adult cohort study focusing on the neurologic complications and mortality after hypernatremia correction in critically ill adults. There wasn't any evidence that rapid correction of hypernatremia was... read more

Fixing Hypernatremia: Acting Fast or Acting Slow?

Guidelines for the Management of Severe TBI

Often, the available evidence is not sufficient to generate guidelines addressing the most critical questions faced by clinicians and patients. Although there have been some major developments in severe traumatic brain... read more

Guidelines for the Management of Severe TBI

Prognostic Value of Spreading Depolarizations in Patients With Severe TBI

In this cohort study of patients with acute brain trauma, spreading depolarizations were predominant but heterogeneous and independently associated with poor neurologic recovery. Monitoring the occurrence of spreading depolarizations... read more

Prognostic Value of Spreading Depolarizations in Patients With Severe TBI

Quantitative EEG for Detection of Brain Ischemia

Electroencephalography (EEG) is a very promising tool for monitoring brain function in real-time in the ICU. There are characteristic changes that occur on EEG in response to brain ischemia, correlating with CBF and brain... read more

Quantitative EEG for Detection of Brain Ischemia

New Hope for Concussions TBI & PTSD

Dr. Larry Komer and Joan Chandler Komer offer new hope to those with brain injuries. Millions of people of all ages experience concussions. Many others have a more serious event known as a traumatic brain injury. Battlefield... read more

New Hope for Concussions TBI & PTSD

Prehospital Rapid Sequence Intubation Improves Functional Outcome for Patients with Severe TBI

In adults with severe traumatic brain injury (TBI), prehospital rapid sequence intubation by paramedics increases the rate of favorable neurologic outcome at 6 months compared with intubation in the hospital. A total of... read more

Prehospital Rapid Sequence Intubation Improves Functional Outcome for Patients with Severe TBI

Predicting Outcome in Patients with Moderate to Severe TBI Using Electroencephalography

Multifactorial Random Forest models using quantitative electroencephalography (qEEG) features, clinical data, and radiological findings have potential to predict neurological outcome in patients with moderate to severe traumatic... read more

Predicting Outcome in Patients with Moderate to Severe TBI Using Electroencephalography

Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications

A comprehensive review of the scientific and clinical studies that have led to the resurgence of interest in hypothermia as a neuroprotective strategy in the treatment of stroke and traumatic brain injury (TBI). Topics... read more

Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications

Is Tranexamic Acid Going to CRASH the Management of TBI?

In the recent CRASH-3 randomized trial, early administration of tranexamic acid (TXA) was associated with a non-significant reduction of head injury-related 28-day mortality in patients with isolated traumatic brain injury... read more

Is Tranexamic Acid Going to CRASH the Management of TBI?

The Oxygen Revolution: The Definitive Treatment of Traumatic Brain Injury (TBI) & Other Disorders

Hyperbaric oxygen therapy (HBOT) is based on a simple idea—that oxygen can be used therapeutically for a wide range of conditions where tissues have been damaged by oxygen deprivation. Inspiring and informative, The... read more

The Oxygen Revolution: The Definitive Treatment of Traumatic Brain Injury (TBI) & Other Disorders

Vasoactive Medication and Randomized Clinical Trials

Vasoactive medication is one of the cornerstones in the treatment of critically ill patients in shock. Shock can be defined as a failure of the circulatory system to provide adequate tissue perfusion resulting in cellular... read more

Vasoactive Medication and Randomized Clinical Trials

Effective Goal-Directed Therapy in TBI Patients May Improve Outcomes

The purpose of this study was to estimate the impact of goal-directed therapy on outcome after traumatic brain injury (TBI). Goal-directed therapy was applied to standardize care in patients with moderate to severe traumatic... read more

Effective Goal-Directed Therapy in TBI Patients May Improve Outcomes

Withdraw Life-Sustaining Treatments for Patients with Severe TBI

The decision to withdraw life support from patients with severe brain injuries is very difficult. In a study conducted in Canadian Medical Association Journal, critical care physicians were asked about the decision-making... read more

Low-value Clinical Practices in Acute Injury Care

This study fills a major knowledge gap on medical procedure overuse in acute injury care. Results will inform research priorities and the development of metrics to measure overuse. This knowledge will provide a solid basis... read more

Low-value Clinical Practices in Acute Injury Care

ICU Patients May Understand Verbal Commands After Acute Brain Injury

A New England Journal of Medicine study shows 1 in 6 clinically unresponsive ICU patients show electroencephalography (EEG) patterns of brain activity when spoken to soon after acute brain injury. A dissociation between the... read more

ICU Patients May Understand Verbal Commands After Acute Brain Injury

Essentials of Neuroanesthesia and Neurointensive Care

This updated second edition of Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care contains the ideal combination of updated information for the practitioner, presented in easy-to-digest short chapters.... read more

Essentials of Neuroanesthesia and Neurointensive Care

Pharmacotherapy in Neurointensive Care

Neurointensive care medicine has experienced great advancements and developments of neuromonitoring techniques, allowing a better comprehension of acute brain injury early phase pathological mechanisms and an overall improvement... read more

Pharmacotherapy in Neurointensive Care

Manual of Traumatic Brain Injury: Assessment and Management

Now completely revised and updated, Manual of Traumatic Brain Injury: Assessment and Management, Second Edition is a comprehensive evidence-based guide to brain injury diagnosis, treatment, and recovery, delivered in a succinct... read more

Manual of Traumatic Brain Injury: Assessment and Management

What influences critical care doctors in withdrawing life support for patients with brain injury?

Decisions to withdraw life support treatments in critically ill patients with severe brain injury are complicated, are based on many factors, and are usually made by critical care physicians and families in the intensive... read more

Sedation in the ICU – Good Past – Better Future?

The concepts for good sedation include defining the range of sedation, the need for agents with rapid response that can be easily and rapidly varied in restless and confused patients, various modes of ventilation, continuous... read more

Sedation in the ICU – Good Past – Better Future?