Predicting Outcome in Patients with Moderate to Severe TBI Using Electroencephalography

Predicting Outcome in Patients with Moderate to Severe TBI Using Electroencephalography

Multifactorial Random Forest models using quantitative electroencephalography (qEEG) features, clinical data, and radiological findings have potential to predict neurological outcome in patients with moderate to severe traumatic... read more

Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications

Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications

A comprehensive review of the scientific and clinical studies that have led to the resurgence of interest in hypothermia as a neuroprotective strategy in the treatment of stroke and traumatic brain injury (TBI). Topics... read more

Is Tranexamic Acid Going to CRASH the Management of TBI?

Is Tranexamic Acid Going to CRASH the Management of TBI?

In the recent CRASH-3 randomized trial, early administration of tranexamic acid (TXA) was associated with a non-significant reduction of head injury-related 28-day mortality in patients with isolated traumatic brain injury... read more

The Oxygen Revolution: The Definitive Treatment of Traumatic Brain Injury (TBI) & Other Disorders

The Oxygen Revolution: The Definitive Treatment of Traumatic Brain Injury (TBI) & Other Disorders

Hyperbaric oxygen therapy (HBOT) is based on a simple idea—that oxygen can be used therapeutically for a wide range of conditions where tissues have been damaged by oxygen deprivation. Inspiring and informative, The... read more

Vasoactive Medication and Randomized Clinical Trials

Vasoactive Medication and Randomized Clinical Trials

Vasoactive medication is one of the cornerstones in the treatment of critically ill patients in shock. Shock can be defined as a failure of the circulatory system to provide adequate tissue perfusion resulting in cellular... read more

Effective Goal-Directed Therapy in TBI Patients May Improve Outcomes

Effective Goal-Directed Therapy in TBI Patients May Improve Outcomes

The purpose of this study was to estimate the impact of goal-directed therapy on outcome after traumatic brain injury (TBI). Goal-directed therapy was applied to standardize care in patients with moderate to severe traumatic... read more

Withdraw Life-Sustaining Treatments for Patients with Severe TBI

The decision to withdraw life support from patients with severe brain injuries is very difficult. In a study conducted in Canadian Medical Association Journal, critical care physicians were asked about the decision-making... read more

Low-value Clinical Practices in Acute Injury Care

Low-value Clinical Practices in Acute Injury Care

This study fills a major knowledge gap on medical procedure overuse in acute injury care. Results will inform research priorities and the development of metrics to measure overuse. This knowledge will provide a solid basis... read more

ICU Patients May Understand Verbal Commands After Acute Brain Injury

ICU Patients May Understand Verbal Commands After Acute Brain Injury

A New England Journal of Medicine study shows 1 in 6 clinically unresponsive ICU patients show electroencephalography (EEG) patterns of brain activity when spoken to soon after acute brain injury. A dissociation between the... read more

Essentials of Neuroanesthesia and Neurointensive Care

Essentials of Neuroanesthesia and Neurointensive Care

This updated second edition of Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care contains the ideal combination of updated information for the practitioner, presented in easy-to-digest short chapters.... read more

Pharmacotherapy in Neurointensive Care

Pharmacotherapy in Neurointensive Care

Neurointensive care medicine has experienced great advancements and developments of neuromonitoring techniques, allowing a better comprehension of acute brain injury early phase pathological mechanisms and an overall improvement... read more

Manual of Traumatic Brain Injury: Assessment and Management

Manual of Traumatic Brain Injury: Assessment and Management

Now completely revised and updated, Manual of Traumatic Brain Injury: Assessment and Management, Second Edition is a comprehensive evidence-based guide to brain injury diagnosis, treatment, and recovery, delivered in a succinct... read more

What influences critical care doctors in withdrawing life support for patients with brain injury?

Decisions to withdraw life support treatments in critically ill patients with severe brain injury are complicated, are based on many factors, and are usually made by critical care physicians and families in the intensive... read more

Sedation in the ICU – Good Past – Better Future?

Sedation in the ICU – Good Past – Better Future?

The concepts for good sedation include defining the range of sedation, the need for agents with rapid response that can be easily and rapidly varied in restless and confused patients, various modes of ventilation, continuous... read more