Tag: therapy
Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock
In patients with cardiogenic shock, no significant difference between Milrinone and Dobutamine was found with respect to the primary composite outcome or important secondary outcomes. A total of 192 participants (96 in... read more
Eosinophilic Esophagitis
Once considered a rare condition, eosinophilic esophagitis is now one of the most common conditions diagnosed during the assessment of feeding problems in children and during the evaluation of dysphagia and food impaction... read more
Trauma Team Dynamics: A Trauma Crisis Resource Management Manual
This is the first book exploring the unique dynamics created by a multidisciplinary trauma team and how crisis management strategies can improve teamwork and communication and, potentially, improve patient resuscitation... read more
Delirium and long term cognition in critically ill patients
Delirium, a form of acute brain dysfunction, is very common in the critically ill adult patient population. Although its pathophysiology is poorly understood, multiple factors associated with delirium have been identified,... read more
Steer Clear of Magnesium for COPD
Knowingly or not, we in emergency medicine tend to lean into the Dutch hypothesis, a 1960s postulate that asthma and COPD are part of a spectrum of common disease (chronic obstructive lung disease), and should be considered... read more
Decreased Mortality in ARDS Patients Treated with Corticosteroids
The use of glucocorticoids might result in reduced mortality in patients with ARDS. Glucocorticoids might be recommended as an adjunct to standard care for ARDS; however, the optimal dose and duration of steroid therapy remains... read more
Effects of Ventilatory Rescue Therapies on the Cerebral Oxygenation of COVID-19 Patients
A new study by Masimo published in Critical Care evaluated the impact of a variety of rescue therapies on the systemic and cerebral oxygenation of mechanically ventilated COVID-19 patients suffering from acute respiratory... read more
Could Physical Therapy Interventions Be Adopted in the Management of Critically Ill Patients with COVID-19?
As part of COVID-19 consequences, it has been estimated that 5% of patients affected by this disease will require admission to the intensive care unit (ICU), and physical therapy techniques have been implemented in patients... read more
Improving Outcomes for Children Requiring ECMO Therapy Following Hematopoietic Stem Cell Transplantation
Pediatric patients posthematopoietic stem cell transplantation supported with extracorporeal membrane oxygenation have improving survival rates over time. With 26% of patients (16/62) surviving to hospital discharge in the... read more
When I Use a Word… Homeostasis and Allostasis
In most cases we do not know who first coined or even used a word. Evidence can generally be found of the earliest instance of a word in written texts, but we do not have a written history of speech nor vocal recordings earlier... read more
Enhancing anti-tumour efficacy with immunotherapy combinations
Several tumour types are responsive to immunotherapy, as shown by regulatory approvals for immune checkpoint inhibitors. However, many patients either do not respond or do not have durable clinical benefit. Thus, there... read more
Safety and Efficacy of B-Cell Depletion with Rituximab for the Treatment of SSc-PAH
B cell depletion therapy is a potentially effective and safe adjuvant treatment for systemic sclerosis-pulmonary arterial hypertension (SSc-PAH). Future studies in these patients can confirm whether the identified biomarkers... read more
Evidence-Based Critical Care: A Case Study Approach
This book provides learners with a unique opportunity by virtue of the format outlined above. Each case presentation has a case vignette, which leads up to an important clinical question, and is followed by additional discussion... read more
The Association of Platelet Decrease Following CRRT Initiation and Increased Rates of Secondary Infections
Platelet count drop by greater than 40% following continuous renal replacement therapy (CRRT) initiation is associated with an increased risk of secondary infection, particularly in patients with thrombocytopenia at the time... read more
