Prognostic Accuracy of POCUS in Patients with Pulseless Electrical Activity

This systematic review and meta-analysis shows that among 1,202 patients across 18 studies, point-of-care ultrasound (POCUS) exhibits high prognostic accuracy for survival to admission (SHA) and moderate accuracy for ROSC... read more

Handbook of ICU EEG Monitoring

Continuous EEG monitoring is an important tool for assessing brain function and allows clinicians to identify malignant EEG patterns quickly and provide more effective care. The revised and updated second edition of Handbook... read more

Handbook of ICU EEG Monitoring

Asthma Course Evaluation in PICU Due to Severe Asthma Exacerbation

Admission to the PICU due to severe asthma exacerbation not only increases the risk of recurrent asthma exacerbations but also serves as a risk factor for stepping up maintenance treatment according to GINA guidelines during... read more

Exploring the Effectiveness of HFNC in the Neurointensive Care Unit

The high flow nasal cannula (HFNC) is becoming increasingly prevalent in both adult and pediatric general intensive care. Despite limited reporting in neurocritical care, we have successfully utilized HFNC in our cohort... read more

Antibiotic Prophylaxis Effectiveness in Polytrauma Patients

The results indicate that antibiotic prophylaxis has no significant effect on mortality and clinical status compared with placebo or standard care in adult polytrauma patients but may reduce the risk of VAP. However,... read more

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices... read more

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences

Hepatic Critical Care

This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is... read more

Hepatic Critical Care

Prescribing Patterns and Effectiveness of Ceftolozane/Tazobactam in Immunosuppressed Patients

Treatment with Ceftolozane/Tazobactam (C/T) resulted in a high rate of clinical success in this real-world cohort of immunosuppressed patients, despite dosing that frequently deviated from labelled dosing. Pseudomonas... read more

Therapeutic Hypothermia After Cardiac Arrest

Therapeutic hypothermia has emerged as a very important treatment option for patients with cardiac arrest as it provides significant protection from developing neurologic injury once the patient has been successfully resuscitated.... read more

Therapeutic Hypothermia After Cardiac Arrest

Primary Management of Polytrauma

This well-illustrated book describes a practical approach to the primary management of patients who have multiple injuries, or polytrauma, with the aim of providing medical and paramedical personnel with the knowledge required... read more

Primary Management of Polytrauma

New Insights: Mortality in Nosocomial Lower Respiratory Tract Infections

This multicenter, multinational study conducted in Europe and Latin America sheds light on the clinical landscape of nLRTI, which continues to be an essential issue in the context of critical care. We provide insights... read more

Rapid and Accurate Sepsis Identification Using AI

This study demonstrates that by providing streamlined predictions using CBC+DIFF data without requiring extensive clinical parameters, the AI-CDSS can be seamlessly integrated into clinical workflows, enhancing rapid, accurate... read more

New Insights: Inhaled Nitric Oxide in Severe COVID-19 Patients

This study provides novel insights into the use of inhaled nitric oxide in severe ARDS COVID-19 patients. Specifically, we demonstrate that the iNO effect of oxygenation improvement is delayed with a prolonged feature that... read more

CAR-T Therapy – Critical Care Considerations of Chimeric Antigen Receptor

Despite significantly improving the treatment of blood cancers, CAR T-cell therapy still faces significant hurdles due to its complex and varied toxicities, which require ongoing research to optimize management; while understanding... read more

Managing Recurrent Septic Shock – Dual Blood Purification with CytoSorb and oXiris

This case report presents a patient with recurrent septic shock who experienced significant clinical improvement after receiving adjunctive treatment with a combination of continuous renal replacement therapy (CRRT) using... read more

Code Sepsis – Early Decompensation and Predictors

Early recognition and management of sepsis within the first hour of a sepsis alert is critical for patient survival, requiring healthcare providers to be trained to identify "red flag" symptoms like rapid breathing (tachypnea)... read more

Predicting Sepsis Outcomes – Efficacy of Early Warning Scores

In resource-limited settings, NEWS proved to be the most effective tool for early risk stratification in sepsis patients. Its adoption could significantly enhance sepsis management and improve outcomes in emergency departments... read more

Handbook of Evidence-Based Critical Care

This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding... read more

Handbook of Evidence-Based Critical Care

Prolonged vs. Intermittent Infusion of Meropenem For Patients with Severe Infection

Prolonged infusion of meropenem is more effective than intermittent infusion in reducing mortality, improving clinical outcomes, and enhancing microbial eradication, without increasing adverse events. These benefits are... read more

Pleural Drainage, Clinical Characteristics, and Management Strategies in the Perioperative Fontan Patient

Prolonged pleural drainage and chylothorax are common in postoperative Fontan patients and are associated with increased morbidity and mortality. Multiple medical and interventional treatment strategies exist and vary between... read more

Handbook for Venous Thromboembolism

A truly practical guidebook for anyone who needs the key information on the diagnosis, management and prevention of venous thromboembolism. Specific areas of focus include understanding the risk factors for VTE and the role... read more

Handbook for Venous Thromboembolism