COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management comprehensively covers COVID-19's impact on the cardiovascular system. Coverage includes the pathophysiology, clinical manifestations, diagnostic... read more

ICU Protocols: A Step-wise Approach, Vol II

ICU Protocols: A Step-wise Approach, Vol II

The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides... read more

COVID-19 Pneumonia: Different Respiratory Treatments for Different Phenotypes?

Type L and Type H patients are best identified by CT scan and are affected by different pathophysiological mechanisms. If not available, signs which are implicit in Type L and Type H definition could be used as surrogates:... read more

Predictive Value of Combined Detection of Serum LGALS3BP and GDF-15 for the Prognosis of ICU Sepsis Patients

Serum LGALS3BP and GDF-15 levels are abnormally elevated in the death group of ICU sepsis patients, suggesting potential application value as prognostic markers for sepsis. The combined use of LGALS3BP and GDF-15 can... read more

Procalcitonin and Neutrophil to Lymphocyte Ratio Trends in ICU Sepsis Patients

Understanding the trends of PCT and NLR concerning the infection source can provide deeper insights into their diagnostic and prognostic capabilities. This comparative analysis of PCT, NLR, and SOFA score trends contributes... read more

Management of Severe Traumatic Brain Injury

Management of Severe Traumatic Brain Injury

"Management of Severe Traumatic Brain Injury" is a practical, comprehensive guide to the treatment of patients (both adults and children) with such injuries, from the time of initial contact through to the rehabilitation... read more

COPD: Heterogeneity and Personalized Treatment

COPD: Heterogeneity and Personalized Treatment

This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented... read more

Functional Dependence Following ICU-treated Sepsis

Sepsis survivorship was associated with a broad range of new impairments and led to functional dependence in around one quarter of patients. Targeted measures are needed to mitigate the burden of this Post-Sepsis-Syndrome... read more

ECLS in Cardiogenic Shock Complicating Acute Myocardial Infarction: Benefit and Harm

Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group. Recently, frequentist analysis showed... read more

Optimal Antibiotic Treatment Duration of Upper and Lower Respiratory Tract Infections

The available evidence for non-ICU community-acquired pneumonia (CAP) and chronic obstructive pulmonary disease (AECOPD) supports a short-course treatment duration of 5 days in patients who have clinically improved. Efforts... read more

Corticosteroid Treatment and Survival in Critically Ill COVID-19 Patients

Our multinational study identified three distinct clinical COVID-19 phenotypes, each exhibiting marked differences in demographic, clinical, and immunological features, and in the response to late and short-term corticosteroid... read more

Critical Care Nephrology and Renal Replacement Therapy in Children

Critical Care Nephrology and Renal Replacement Therapy in Children

Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more

Conservative or Liberal Oxygen Targets in Patients on VA-ECMO

In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more

Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover... read more

A prediction model for nonresponsive outcomes in critically ill patients with ARDS undergoing prone position ventilation

In this study, a risk prediction model for nonresponse to prone position ventilation in acute respiratory distress syndrome (ARDS) patients was constructed, which demonstrated good predictive value and clinical utility. Early... read more

Predictors of High-flow Nasal Cannula Failure in COVID-19 Patients

A retrospective cohort study was conducted during the months of March and May 2021. Data collection was based on a follow-up of 156 hospitalized patients with a diagnosis of COVID-19 who were users of high-flow nasal cannula... read more

Troponin Role in the Diagnosis and Treatment of Acute Pulmonary Embolism

Acute pulmonary embolism (APE) is a cardiovascular disease with severe consequences, wherein cardiac troponin (Tn) plays a pivotal role in diagnosis and treatment. This article reviews the various roles of Tn in managing... read more