Remestemcel-L reduces ARDS mortality in those under 65 years old

Remestemcel-L reduces ARDS mortality in those under 65 years old

New data shows patients with COVID-19-related Acute Respiratory Distress Syndrome (ARDS) were up to 75 percent less likely to die when treated with remestemcel-L and dexamethasone. The data shows remestemcel-L reduced... read more

POCUS of the Heart and Lungs in Patients with Respiratory Failure

POCUS of the Heart and Lungs in Patients with Respiratory Failure

Point-of-care ultrasound (POCUS) is a focus oriented tool for differentiating among cardiopulmonary diseases. Its value in the hands of emergency physicians, with various ultrasound experience, remains uncertain. We tested... read more

Decreased Mortality in ARDS Patients Treated with Corticosteroids

Decreased Mortality in ARDS Patients Treated with Corticosteroids

The use of glucocorticoids might result in reduced mortality in patients with ARDS. Glucocorticoids might be recommended as an adjunct to standard care for ARDS; however, the optimal dose and duration of steroid therapy remains... read more

Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover... read more

Critical Care Nephrology and Renal Replacement Therapy in Children

Critical Care Nephrology and Renal Replacement Therapy in Children

Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more

Cytokine Adsorption Effect on Survival and Circulatory Stabilization in Patients Receiving ECPR

Cytokine Adsorption Effect on Survival and Circulatory Stabilization in Patients Receiving ECPR

Even after the introduction of extracorporeal cardiopulmonary resuscitation (ECPR), survival after cardiac arrest remains poor. Excess release of vasoactive cytokines may be a reason for cardiovascular instability and death... read more

Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins

Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins

A new Phase 3 trial to test the safety and efficacy of therapeutics for COVID-19 has begun enrolling patients hospitalized with life-threatening cases of COVID-19, including those with acute respiratory failure. The trial... read more

Validation of Sputum Gram Stain for Treatment of CAP and HCAP

Validation of Sputum Gram Stain for Treatment of CAP and HCAP

The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia... read more

Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid

Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid

Combinations of coagulation factor concentrates suspended in albumin solutions can restore thromboelastometry parameters in the absence of plasma. This kind of artificial colloid fluids with coagulation-restoring characteristics... read more

Patient’s Clinical Presentation and CPPopt Availability: Any Association?

Patient’s Clinical Presentation and CPPopt Availability: Any Association?

In this retrospective multicenter study, none of the selected admission and treatment variables were related to the CPPopt yield. The median CPPopt yield was 80.7% (interquartile range 70.9–87.4%). None of the selected... read more

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more

Peripheral Arteriovenous Malformations: Classification and Endovascular Treatment

Peripheral Arteriovenous Malformations: Classification and Endovascular Treatment

In this review we cover the classification and endovascular management of arteriovenous malformations (AVMs). We begin by viewing AVMs in relation to the broader class of congenital vascular malformations and subsequently... read more

Operative Techniques and Recent Advances in Acute Care and Emergency Surgery

Operative Techniques and Recent Advances in Acute Care and Emergency Surgery

The aim of this book is to identify and shed new light on the main surgical practices involved in acute care and trauma surgery. Adopting an evidence-based approach, a multidisciplinary team of surgeons and intensivists... read more

Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments

Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments

In this study, a quality improvement intervention that trained physicians to communicate and plan ICU care with family members of critically ill patients in the ICU using TLTs was associated with improved quality of family... read more