Tag: treatment
Mayo Clinic Critical and Neurocritical Care Board Review
Mayo Clinic Critical and Neurocritical Care Board Review is an all-inclusive review of the pathophysiology and care of the neurocritically ill and critically ill patient. The book reviews the core major critical care... read more
Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock
PAC usage in cardiogenic shock (CS) is being revitalized by recent positive analyses of large registry and administrative databases. To realize the full potential of pulmonary artery catheters (PAC), more research is urgently... read more
Isavuconazole vs. Voriconazole for Antifungal Prophylaxis in Lung Transplant Recipients
Isavuconazole was effective and well tolerated as antifungal prophylaxis following lung transplantation. A single-center, retrospective study of patients who received isavuconazole (September 2015–February 2018) or voriconazole... read more
Ketamine for Treatment-Resistant Depression
This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine... read more
Drug Treatments for COVID-19
Corticosteroids and interleukin-6 inhibitors probably confer important benefits in patients with severe covid-19. Janus kinase inhibitors appear to have promising benefits, but certainty is low. Azithromycin, hydroxychloroquine,... read more
Management of Severe Traumatic Brain Injury
"Management of Severe Traumatic Brain Injury" is a practical, comprehensive guide to the treatment of patients (both adults and children) with such injuries, from the time of initial contact through to the rehabilitation... read more
NeuroRx Announced Completion of Data Analysis for COVID-19 Treatment Respiratory Failure
NeuroRx, Inc. announced completion of top line data analysis of the 60-day results in its phase 2b/3 clinical trial, conducted under FDA Fast Track Designation, of ZYESAMI™ (aviptadil acetate) for the treatment of critically-ill... read more
SARS-CoV Replication-transcription Complex Can Initiate RNA Synthesis
How viruses from the Coronaviridae family initiate viral RNA synthesis is unknown. Here we show that the SARS-CoV-1 and −2 Nidovirus RdRp-Associated Nucleotidyltransferase (NiRAN) domain on nsp12 uridylates the viral cofactor... read more
Correlation Between COVID-19 Mortality and Autoantibodies in Patients Treated with Corticosteroids
Auto-reactivity in COVID-19 is increasingly being recognized and may identify a group of patients with inflammation severe enough to result in loss of self-tolerance. Corticosteroids are potent anti-inflammatory agents and... read more
General Practitioners’ Views in Caring for Patients After Sepsis
General Practitioners provide continuity of care to patients surviving sepsis. Better communication at the ICU-GP interface and training in management of long-term complications of sepsis may be helpful to improve sepsis... read more
Haloperidol and Quetiapine for the Treatment of ICU-Associated Delirium in a Tertiary Pediatric ICU
In our small, single-center study, patients treated with haloperidol or quetiapine showed no short-term improvement in delirium screening scores after starting treatment when compared with untreated, propensity score-matched... read more
Outcomes and Risk Factors Associated with COVID-19 Infection of Patients with Multiple Sclerosis
In this registry-based cross-sectional study, increased disability was independently associated with worse clinical severity including death from COVID-19. Other risk factors for worse outcomes included older age, Black race,... read more
Effect of Intermediate-Dose vs. Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, ECMO Treatment, or Mortality Among Patients With COVID-19 in ICU
Among patients admitted to the ICU with COVID-19, intermediate-dose prophylactic anticoagulation, compared with standard-dose prophylactic anticoagulation, did not result in a significant difference in the primary outcome... read more
Prophylaxis for Pneumocystis Pneumonia in non‐HIV Immunocompromised Patients
Our review shows that TMP/SMX prophylaxis is highly effective for prevention of Prophylaxis for Pneumocystis Pneumonia (PCP) in patients with hematological malignancies, bone marrow transplantation and solid organ transplantation,... read more
