VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a high mortality. This study assessed venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for sepsis-induced cardiogenic shock refractory... read more

From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response

From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response

Between June 18 and Aug 3, 2020, Ministry of Health of the Russian Federation enrolled 76 participants to the two studies (38 in each study). In each study, 9 volunteers received rAd26-S in Phase 1, nine received rAd5-S in... read more

COVID-19: A Critical Analysis of Chloroquine and Hydroxychloroquine Clinical Pharmacology

COVID-19: A Critical Analysis of Chloroquine and Hydroxychloroquine Clinical Pharmacology

Chloroquine and hydroxychloroquine have been used for over 60 years in the treatment of malaria, amoebic liver abscess, and several rheumatological conditions, but their clinical pharmacology is not well understood. COVID-19... read more

Hydroxychloroquine With or Without Azithromycin

Hydroxychloroquine With or Without Azithromycin

Among patients hospitalized with mild-to-moderate COVID-19, the use of hydroxychloroquine, alone or with azithromycin, did not improve clinical status at 15 days as compared with standard care. A total of 667 patients... read more

Effect of Hydrocortisone on Mortality and Organ Support in Patients with Severe COVID-19

Effect of Hydrocortisone on Mortality and Organ Support in Patients with Severe COVID-19

Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority... read more

Scvo2 in Sepsis: A Measurement Provided by Respiratory Care Practitioners

Scvo2 in Sepsis: A Measurement Provided by Respiratory Care Practitioners

When treating patients with sepsis, intensive care unit (ICU) and emergency department clinicians have learned that improved outcomes occur when staff members work together as a team. This article outlines the value of central... read more

Prone Positioning in Non-intubated Patients with COVID-19

Prone Positioning in Non-intubated Patients with COVID-19

As the COVID-19 pandemic has put severe stress and strain on the capacity of hospitals around the world, concerted efforts have been made to evaluate therapeutics aimed at preventing the need for mechanical ventilation. The... read more

A Randomised Trial of High-flow Nasal Cannula in Infants with Moderate Bronchiolitis

A Randomised Trial of High-flow Nasal Cannula in Infants with Moderate Bronchiolitis

In patients with moderate bronchiolitis, there was no evidence of lower rate of escalating respiratory support among those receiving HFNC therapy. The analyses included 268 patients among the 2621 infants assessed for... read more

Hepatic Critical Care

Hepatic Critical Care

This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is... read more

Pediatric Critical Care and COVID-19

Pediatric Critical Care and COVID-19

We provide early clinical and laboratory data about critical pediatric COVID-19, which suggest a variable disease but generally good outcomes compared with adults. Targets for research include the course of organ failure... read more

Serum Levels of Receptor-interacting Protein Kinase-3 in Patients with COVID-19

Serum Levels of Receptor-interacting Protein Kinase-3 in Patients with COVID-19

Patients with coronavirus disease 2019 (COVID-19) can develop acute respiratory distress syndrome (ARDS), which has been linked to poor prognosis and is a major contributor to patient death. A better understanding of the... read more

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

The concept of vaECMO treatment alone might be a valuable alternative in selected patients with massive PE and cardiogenic shock, in whom thrombolytic therapy might not unload the RV fast enough. We present a case of a... read more

Surgery of the Inferior Vena Cava

Surgery of the Inferior Vena Cava

This book addresses an urgent need, offering an updated, detailed and multidisciplinary review of surgery of the inferior vena cava (IVC). Over the past two decades, tremendous advances have been made in this field and related... read more

Perioperative Management of Glucose-lowering Drugs in Type 2 Diabetes Patients

Perioperative Management of Glucose-lowering Drugs in Type 2 Diabetes Patients

Patients with type 2 diabetes are commonly referred for elective or emergency surgery. In case of scheduled surgical procedures, previous guidelines recommended to withhold oral glucose-lowering drugs. Based on recent... read more