Tag: treatment
Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam
This case demonstrates the importance of rapid recognition and treatment of hydroxychloroquine poisoning. We anticipate that clinicians may be asked to recognize and manage this toxidrome in increasing frequency as attention... read more
Spotting the Clotting: Hypercoagulopathy in COVID-19
Evolving experience with TEG, clotting parameters, treatment considerations, and ongoing data gathering will help us better understand if antiplatelet therapy with aspirin or clopidogrel or anticoagulant treatment with traditional... read more
COVID-19: 10 Things I Wished I’d Known Some Months Ago
The COVID-19 pandemic is ongoing and spreading, affecting individuals in over 200 countries now. While COVID-19-related articles are being published every day, including guidelines of optimal clinical management, there are... read more
Thousands Who Got COVID-19 in March Are Still Sick
COVID-19 has existed for less than six months, and it is easy to forget how little we know about it. The standard view is that a minority of infected people, who are typically elderly or have preexisting health problems,... read more
Sharing Data is the Key to Unlocking Remdesivir Challenges
Critical care teams should consider using remdesivir to treat patients with severe acute SARS-CoV-2 infection, but supply of the drug is limited and best practices for maximizing its effectiveness are not completely understood. The... read more
Hydroxychloroquine or Azithromycin for COVID-19 Treatment
The use of hydroxychloroquine, azithromycin, or both were not associated with differences in in-hospital mortality. Cardiac arrest was more likely in patients receiving hydroxychloroquine and azithromycin. In this retrospective,... read more
Risk Score for Development of Critical Illness in Patients with COVID-19
In this study, we developed a risk score and web-based calculator to estimate the risk of developing critical illness among patients with COVID-19 based on 10 variables commonly measured on admission to the hospital. Estimating... read more
Rapid Development of an Inactivated Vaccine Candidate for COVID-19
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are currently no SARS-CoV-2-specific... read more
What’s Working for COVID-19 Patients in the Epicenter
Our large tertiary care ED in Queens, NY, usually sees more than 100,000 adults a year. As we write this, we have 850 COVID-19-likely or -positive patients (several hundred above our bed capacity just one month ago), more... read more
COVID-19: Two More Trials Just Published on Remdesivir
Currently, there are no approved medications for the treatment of COVID-19, but, there are many investigational agents that have shown antiviral activity against SARS-CoV-2 in vitro. Unfortunately in vitro studies do... read more
Pandemic Science Out of Control
A toxic legacy of poor-quality research, media hype, lax regulatory oversight, and vicious partisanship has come home to roost in the search for effective treatments for COVID-19. The rush to offer unproven treatments... read more
Low-dose Dopamine in Patients with Early Renal Dysfunction
Administration of low-dose dopamine by continuous intravenous infusion to critically ill patients at risk of renal failure does not confer clinically significant protection from renal dysfunction. The groups assigned dopamine... read more
Expert Panel Develops NIH Treatment Guidelines for COVID-19
A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COVID-19). These guidelines, intended for healthcare providers, are based on published and preliminary... read more
Palliative Care Considerations For Patients With Cardiovascular Disease Under COVID-19
COVID-19 has dramatically altered our world, health care systems and supply chains. Older adults with cardiovascular disease especially those over 80 years suffer disproportionately. This pandemic has stressed the capacity... read more