Tag: treatment
Many Doctors Have Distorted Perceptions of the Value of Medical Tests
In 2014, the Canadian Task Force on Preventive Health Care recommended against the prostate-specific antigen (PSA) test used to screen for prostate cancer in healthy men, concluding that it results in substantial harms via... read more
Management of the Critically Ill Adult Chimeric Antigen Receptor-T Cell Therapy Patient
Until modifications in chimeric antigen receptor T-cell therapy decrease their toxicities, the intensivist will play a leading role in the management of critically ill chimeric antigen receptor T-cell patients. As this novel... read more
High-flow Nasal Cannula Oxygen Therapy for AHRF in Patients with CLD
A high-flow nasal cannula (HFNC) is a high-flow oxygen supply device developed in recent years and is increasingly being used to treat acute hypoxemic respiratory failure (AHRF) in intensive care unit (ICU). Patients with... read more
The utility of biomarkers in traumatic brain injury clinical management
Currently, TBI management is guided by clinical histories and neuroimaging techniques. While these techniques may be advanced, they are more costly than serum analysis, involve exposure to ionizing radiations, and have certain... read more
Short People Have Higher Risk Of Dying In The ICU
Researchers of a new study have found a link between a patient's height and odds of survival in the intensive care unit (ICU) of the hospital. The study, published in the journal Intensive Care Medicine on Dec. 23, show that... read more
Patient-tailored Triage Decisions by Anesthesiologist-staffed Prehospital Critical Care Teams
The primary objective was to estimate the incidence of patients in the Central Denmark Region triaged to bypass the local emergency department without being part of a predefined fast-track protocol. The secondary objective... read more
Effect of Levocarnitine vs Placebo as an Adjunctive Treatment for Septic Shock
In this dose-finding, phase 2 adaptive randomized trial, patients with septic shock and moderate organ dysfunction were treated early in the course of illness with low (6 g), medium (12 g), or high (18 g) doses of levocarnitine... read more
Tigecycline in Critically Ill Patients on Continuous RRT
Despite high dialysability, dialysis clearance displayed only a minor contribution to tigecycline elimination, being in the range of renal elimination in patients without AKI. No dose adjustment of tigecycline seems necessary... read more
New Sickle Cell Test Can Transform Screening
Sickle cell disease is common throughout much of sub-Saharan Africa. It affects up to 3% of births in some areas and is associated with very high mortality. Many cases go undiagnosed in regions where there are few resources,... read more
Vitamin Treatment For Sepsis Is Put To The Test
Dr. Jonathan Sevransky was intrigued when he heard that a well-known physician in Virginia had reported remarkable results from a simple treatment for sepsis. Could the leading cause of death in hospitals really be treated... read more
Would A Change in Nomenclature for ICUs Promote Less Aggressive Care?
The term "intensive care unit" (ICU) was originally meant to refer to the intensity of the resources allocated to patient care. Today, however, ICU refers more to the intensity of the interventions undergone by the patient.... read more
A Multicentre Randomised Controlled Trial of Levetiracetam vs. Phenytoin for Convulsive Status Epilepticus in Children
Convulsive status epilepticus (CSE) is the most common life-threatening childhood neurological emergency. Despite this, there is a lack of high quality evidence supporting medication use after first line benzodiazepines,... read more
Rapid Bedside Evaluation of Seizures in the ICU by Listening to the Sound of Brainwaves
The Ceribell EEG System enabled rapid acquisition of electroencephalography (EEG) in patients at risk for non-convulsive seizures and aided clinicians in their evaluation of encephalopathic ICU patients. The ease of use and... read more
Delirium in Critical Illness: Haloperidol vs Ziprasidone?
Delirium is defined as an acute disorder of consciousness which can occur in up to 80% of mechanically ventilated ICU patients. This acute cognitive dysfunction is associated with prolonged hospital stay, increased mortality,... read more
Critical Care Medicine: The Essentials and More
With a full-color design and concise, easy-to-read chapters, Critical Care Medicine: The Essentials and a Bit More covers the core elements of critical care, with a unique focus on the pathophysiology underlying clinical... read more
