Pediatric Pneumonia Research Priorities in the Context of COVID-19

Pediatric Pneumonia Research Priorities in the Context of COVID-19

Operational research on health system capacities, and evaluating optimized delivery of existing treatments, diagnostics and case management approaches are needed. This list should act as a catalyst for collaborative research,... read more

Patients’ Perspectives on Point-of-Care Diagnostics in Acute COPD Exacerbations

Patients’ Perspectives on Point-of-Care Diagnostics in Acute COPD Exacerbations

Patients' perspectives showed that point-of-care diagnostics and treatment of acute COPD in exacerbation was considered a qualitative offer by the patients and their relatives. At the same time, it was crucial that the emergency... read more

Information Transfer as a Strategy to Improve Safety in ICU

Information Transfer as a Strategy to Improve Safety in ICU

In an Intensive Care Unit (ICU), we attend people with a wide range of pathologies. All the information obtained from monitoring our critical patients, diagnostic and therapeutic techniques, responses to treatments, action... read more

Effect of Intra-arrest Transport, ECPR, and Treatment on Functional Neurologic Outcome

Effect of Intra-arrest Transport, ECPR, and Treatment on Functional Neurologic Outcome

Among patients with refractory out-of-hospital cardiac arrest, the bundle of early intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and invasive assessment and treatment did not significantly improve... read more

Cancer Treatments Not Associated with Inferior COVID-19 Outcomes

Cancer Treatments Not Associated with Inferior COVID-19 Outcomes

The findings of this study of patients with active cancer suggest that recent systemic anticancer treatments (SACTs) is not associated with inferior outcomes from COVID-19 infection. This has relevance for the care of... read more

Deconstructing the Way We Use Pulmonary Function Test Race-Based Adjustments

Deconstructing the Way We Use Pulmonary Function Test Race-Based Adjustments

Race is a social construct. It is used in medical diagnostic algorithms to adjust the readout for spirometry and other diagnostic tests. The authors review historic evidence about the origins of race adjustment in spirometry,... read more

Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19

Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19

At approximately 4 months after acute illness, cognitive dysfunction, emotional distress, and functional decline were common among a diverse clinical sample of COVID-19 survivors varying in acute illness severity. Patients... read more

Leriche Syndrome Diagnosed Due to Polytrauma

Leriche Syndrome Diagnosed Due to Polytrauma

In this case, conservative therapy was initially chosen for Leriche syndrome. However, the complex factors in the acute phase of trauma led to development of hemorrhagic necrosis, requiring amputation of the lower extremity.... read more

Hemodynamic Status During Endovascular Stroke Treatment

Hemodynamic Status During Endovascular Stroke Treatment

In our protocol-based setting, intraprocedural pre-recanalization BP reductions during endovascular therapy were not associated with functional outcome. However, higher intraprocedural pre-recanalization SBP and MAP were... read more

Cluster ICU Treatment Strategies for TBI by Hospital Treatment Preferences?

Cluster ICU Treatment Strategies for TBI by Hospital Treatment Preferences?

Although correlations between treatment policies within domains were found, the failure to cluster hospitals indicates that a specific treatment choice within a domain is not a proxy for other treatment choices within or... read more

Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis

Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis

Bacterial sepsis patients had early, severe inflammation, profound immune suppression, and life-threatening organ dysfunction that resolved over time; SARS-CoV-2 patients had less severe early inflammation and organ dysfunction... read more

ARDS Subphenotypes Validation and Utility Identified by Machine-learning Models

ARDS Subphenotypes Validation and Utility Identified by Machine-learning Models

Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. Application of these models can provide valuable prognostic information and could inform management strategies... read more

Coupled Plasma Filtration and Adsorption for Septic Shock Treatment

Coupled Plasma Filtration and Adsorption for Septic Shock Treatment

Early deaths are likely related to the ongoing CPFA treatment, for reasons that if identified could allow some deaths to be prevented. We hypothesize a connection to hemodynamic instability consequent on renal replacement... read more

ICU Quick Drug Guide

ICU Quick Drug Guide

Offering essential, evidence-based practice guidelines specifically for the critical care setting, ICU Quick Drug Guide contains up-to-date information in a quick-access format. This portable handbook provides fast, accurate... read more