Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients

Among adults receiving mechanical ventilation in the ICU, adding early in-bed Cycling to usual physiotherapy did not improve physical function at 3 days after discharge from the ICU compared with Usual physiotherapy alone.... read more

Noninvasive Ventilation for Preoxygenation during Emergency Intubation

Among critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation resulted in a lower incidence of hypoxemia during intubation than preoxygenation with an oxygen mask. Among the 1,301... read more

The role of pleural pressure and airway closure during mechanical ventilation

Related to our paper, Van Egmond et al. highlighted key physiological concepts we must be aware of. We believe, however, that the described physiological com-plexity has limited impact on the daily use of esophageal pressure... read more

Two weaning strategies for NIV in COPD patients with ARF

Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

We present a case of 43-year-old male patient with broadly by Omalizumab, Mepolizumab and Benralizumab pretreated allergic asthma, who suffered a near fatal exacerbation, triggered by an influenza A infection. Due to... read more

Prone Positioning During ECMO for Severe ARDS

The ongoing debate on optimal extracorporeal membrane oxygenation (ECMO) care emphasizes the need for rigorous investigation, acknowledging the value of observational data in routine The PRONECMO study, with its pragmatic... read more

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the COVID-19 pandemic, and offers practical information on how to manage them. Older... read more

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more

Intravenous Vitamin C for COVID-19 Patients

In hospitalized patients with COVID-19, vitamin C had low probability of improving the primary composite outcome of organ support–free days and hospital survival. Enrollment was terminated after statistical triggers... read more

Effect of Mechanical Ventilation Under Intubation on Respiratory Tract Change of Bacterial Count

Mechanical ventilation under intubation may cause dysregulation of lower respiratory microbiota in rats. The most common 'second strike' in mechanically ventilated patients is a pulmonary infection caused by the ease with... read more

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange vs. Conventional Facemask Breathing for Preoxygenation During Rapid Sequence Induction

Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE), if used for pre-oxygenation and apnoeic oxygenation, has the propensity to extend the safe apnoea time and thereby decrease the incidence of desaturation... read more

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

The study revealed that the utilization of non-ICU sophisticated ventilators was linked to a higher mortality rate when compared to standard ICU ventilators in COVID-19 patients with ARDS. However, given the shortage and... read more

Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

This book is an introduction to a comprehensive analysis of recent advances and clinical research in noninvasive mechanical ventilation (NIV) in Pulmonary, Critical Care, and Sleep Medicine. The objective of the book is to... read more

Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

ReddyPort Non-Invasive Ventilation Device Cleared By FDA

ReddyPort announced today that the US Food and Drug Administration (FDA) granted 510(k) premarket clearance for the ReddyPort elbow device used in non-invasive ventilation (NIV). "ReddyPort's patented elbow is central... read more

Ciprofol Sedation Efficacy and Safety in Mechanical Ventilated ICU Patients

Ciprofol was well tolerated, with a noninferior sedation profile to propofol in Chinese ICU patients undergoing MV for a period of 6–24 hours. Of the 135 patients enrolled, 129 completed the study. The primary endpoint-sedation... read more

Prone vs. Supine Position Ventilation in Intubated COVID-19 Patients

Whether prone positioning of patients undergoing mechanical ventilation for COVID-19 pneumonia has benefits over supine positioning is not clear. We conducted a systematic review with meta-analysis to determine whether prone... read more

Acute Respiratory Distress Syndrome: Advances in Diagnostic Tools and Disease Management

Divided into thirteen chapters, this book provides a wealth of research-oriented findings and practical guidance, ranging from the definition, epidemiology and pathophysiology, to the diagnosis and management of the disease.... read more

Acute Respiratory Distress Syndrome: Advances in Diagnostic Tools and Disease Management

Mechanical Ventilation from Pathophysiology to Clinical Evidence

This new book aims to give a comprehensive overview of the current challenges and solution posed to the health care professionals who need to use mechanical ventilation to treat their patients. Mechanical ventilation is... read more

Mechanical Ventilation from Pathophysiology to Clinical Evidence

Emergency Department Crowding Impact on Lung Protective Ventilation

Obtaining definitive control of the airway, when indicated, is the responsibility of the emergency medicine physician. Traditionally patients were managed on the ventilator with lung volumes of 10 – 15 ml/kg. However,... read more

Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Compared with standard calorie and protein targets, early calorie and protein restriction did not decrease mortality but was associated with faster recovery and fewer complications. Of 3,044 patients randomly assigned... read more

COVID-19 in Solid Organ Transplant Recipients

Solid Organ Transplant (SOT) recipients are at high risk of severe coronavirus disease-2019. Prior to the availability of vaccination, passive immunotherapies and effective antiviral therapeutics, the outcomes of COVID-19... read more