Pressure Support vs. Spontaneous Ventilation during Anesthetic Emergence – Effect on Postoperative Atelectasis

Pressure Support vs. Spontaneous Ventilation during Anesthetic Emergence – Effect on Postoperative Atelectasis

The incidence of postoperative atelectasis was lower in patients undergoing either laparoscopic colectomy or robot-assisted prostatectomy who received pressure support ventilation during emergence from general anesthesia... read more

Noninvasive Ventilation and Outcomes in Bronchiolitis

Noninvasive Ventilation and Outcomes in Bronchiolitis

In a large cohort of infants at children’s hospitals, noninvasive and invasive ventilation increased significantly from 2010 to 2018. Hospital-level noninvasive ventilation utilization was not associated with a reduction... read more

Non-invasive vs. Invasive Respiratory Management Strategies in AHRF Patients

Non-invasive vs. Invasive Respiratory Management Strategies in AHRF Patients

When performing non-invasive ventilation among patients with de novo acute hypoxaemic respiratory failure (AHRF), it is important to avoid excessive tidal volume and lung injury. Although pressure support is needed for... read more

Respiratory Monitoring in Mechanical Ventilation: Techniques and Applications

Respiratory Monitoring in Mechanical Ventilation: Techniques and Applications

This book covers the up-to-date advancement of respiratory monitoring in ventilation support as well as detecting the physiological responses to therapeutic interventions to avoid complications. Mechanical ventilation nowadays... read more

Facemask vs. Helmet – Noninvasive Ventilation

Facemask vs. Helmet – Noninvasive Ventilation

We use Noninvasive ventilation (NIV) to treat various disease processes, such as acute hypercapnic and hypoxemic respiratory failure, post-extubation failure, and neuromuscular diseases. Data supports NIV use in some conditions,... read more

Weaning Methods From Mechanical Ventilation in Adult Patients

Weaning Methods From Mechanical Ventilation in Adult Patients

In general consideration, our study provided evidence that weaning with proportional assist ventilation has a high probability of being the most effective ventilation mode for patients with mechanical ventilation regarding... read more

Head Rotation in Anaesthetised Apnoeic Patients Significantly Increases Mask Ventilation Efficiency

Head Rotation in Anaesthetised Apnoeic Patients Significantly Increases Mask Ventilation Efficiency

Head rotation of 45° in anaesthetised apnoeic adults significantly increases the efficiency of mask ventilation compared with the neutral head position. Head rotation is an effective alternative to improve mask ventilation... read more

Endothelial Glycocalyx Degradation Contributes to Metabolic Acidosis in Children After Cardiopulmonary Bypass Surgery

Endothelial Glycocalyx Degradation Contributes to Metabolic Acidosis in Children After Cardiopulmonary Bypass Surgery

Our data show that metabolic acidosis (increased strong ion gap) is associated with plasma concentration of heparan sulfate, a negatively charged glycosaminoglycan cleaved from the endothelial glycocalyx during cardiopulmonary... read more

The Unsung Heroes: Respiratory Therapists

The Unsung Heroes: Respiratory Therapists

Working day after day, year after year, in a busy high acuity ICU, we all have become a "second family." The public doesn't hear much about respiratory therapists, especially during this COVID nightmare. But they have... read more

Mechanically Ventilated COVID-19 Patients: Long-term Survival Study

Mechanically Ventilated COVID-19 Patients: Long-term Survival Study

The long-term survival of mechanically ventilated patients with severe COVID-19 reaches more than 50% and may help to provide individualized risk stratification and potential treatments. 868 patients were included (median... read more

ARDS vs. PseudoARDS – Failure of the Berlin Definition

ARDS vs. PseudoARDS – Failure of the Berlin Definition

True ARDS might be defined as a histological diagnosis involving diffuse alveolar damage throughout the lungs (characterized by hyaline membrane formation and thickening of the alveolar walls). PseudoARDS refers to patients... read more

Diaphragm Dysfunction After Cardiac Surgery

Diaphragm Dysfunction After Cardiac Surgery

Symptomatic diaphragmatic dysfunction was found in 7.6% of patients after cardiac surgery. It led to an increase of respiratory complications, such as pneumonia, prolonged ventilation, and intensive care. Coronary bypass... read more

Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia

Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia

Carbapenem-based empiric regimens were associated with lower mortality rates compared with non-carbapenems, largely driven by trials of ventilator-associated pneumonia (VAP). The mortality effect was not observed in trials... read more

Brain–lung Interactions and Mechanical Ventilation in Patients with Isolated Brain Injury

Brain–lung Interactions and Mechanical Ventilation in Patients with Isolated Brain Injury

During the last decade, experimental and clinical studies have demonstrated that isolated acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and systems. Of all potential target organs... read more

Approach to the Critically Ill Poisoned Patient

Approach to the Critically Ill Poisoned Patient

Toxicology histories are notoriously unreliable. Any available medical records, especially medication lists. Timing & amount of ingestions. Immediate vs. sustained-release formulations. Consider inquiring specifically... read more

Waveform Capnography in the Intubated Patient

Waveform Capnography in the Intubated Patient

Waveform capnography is emerging as a standard monitoring tool to improve safety among intubated patients. Failure to use waveform capnography contributed to >70% of ICU-related airway deaths in the NAP4 audit. Capnography... read more

Higher vs. Lower PEEP in ARDS Patients

Higher vs. Lower PEEP in ARDS Patients

In our meta-analysis of RCTs, higher positive end-expiratory pressure (PEEP), compared with lower PEEP, was not associated with mortality in patients without acute respiratory distress syndrome (ARDS) receiving invasive mechanical... read more