Practical Issues Updates in Anesthesia and Intensive Care

This book describes the state of the art concerning some of the most hotly debated topics in anesthesia and intensive care and is at the same time intended to serve as a useful practical guide that will assist in improving... read more

Practical Issues Updates in Anesthesia and Intensive Care

External Chest-wall Compression in Prolonged COVID-19 ARDS with Low-compliance

SARS-CoV-2 can lead to severe respiratory failure (C-ARDS) with some clinical and radiological characteristics that match the presentation of acute respiratory distress syndrome (ARDS). The management of mechanical ventilation... read more

External Chest-wall Compression in Prolonged COVID-19 ARDS with Low-compliance

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

The Pediatric Acute Lung Injury Consensus Conference “at-risk for pediatric acute respiratory distress syndrome” criteria identify critically ill children at high risk of pediatric acute respiratory distress syndrome... read more

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

Weaning from Ventilation and Extubation of Children in Critical Care

By reading this article, you should be able to: - Identify the predictors of successful extubation in pediatric ICU (PICU) patients. - Describe the factors affecting mechanical ventilator weaning in PICU patients. -... read more

Weaning from Ventilation and Extubation of Children in Critical Care

Staff Experiences Relating to Early Mobilisation of Mechanically Ventilated Patients in Intensive Care

Early mobilisation of mechanically ventilated patients has been suggested to be effective in mitigating muscle weakness, yet it is not a common practice. Understanding staff experiences is crucial to gain insights into what... read more

Staff Experiences Relating to Early Mobilisation of Mechanically Ventilated Patients in Intensive Care

Optimal Respiratory Support for COVID-19 Patients

Noninvasive respiratory support is an essential component of critical care. Both noninvasive ventilation, with its different interface types and modes (including helmet and face masks), and high-flow nasal oxygen (HFNO) are... read more

Optimal Respiratory Support for COVID-19 Patients

Ventilator Capacity Management Queuing Model During COVID-19 Pandemic

We applied a queuing model to inform ventilator capacity planning during the first wave of the COVID-19 epidemic in the province of British Columbia (BC), Canada. The core of our framework is a multi-class Erlang loss model... read more

Ventilator Capacity Management Queuing Model During COVID-19 Pandemic

Lessons Learned From the First 50 COVID-19 Critical Care Transfer Missions

Critically ill COVID-19 patients have highly complex medical needs during transport. Critical care transfer of COVID-19-positive patients by civilian HEMS services, including air transfer, can be achieved safely with specific... read more

Lessons Learned From the First 50 COVID-19 Critical Care Transfer Missions

Non-Invasive Ventilation and Weaning: Principles and Practice, Second Edition

Now in full-colour, this eagerly-anticipated second edition continues to be the most comprehensive resource available on non-invasive ventilation (NIV), both in the hospital and at home. Reflecting a global perspective with... read more

Non-Invasive Ventilation and Weaning: Principles and Practice, Second Edition

Prone Positioning Effect on Adult Patients Survival Receiving vvECMO for ARDS

This systematic review and meta-analysis of 13 studies (total N = 1836) showed that PP of acute respiratory distress syndrome (ARDS) patients receiving venovenous ECMO (vvECMO) was associated with a significant improvement... read more

Prone Positioning Effect on Adult Patients Survival Receiving vvECMO for ARDS

ECMO. Extracorporeal Membrane Oxygenation

Extracorporeal membrane oxygenation (ECMO), is a rapidly developing technology for supporting or even replacing heart and/or lung functions for days or weeks, giving the time for recovery, other therapeutic interventions... read more

ECMO. Extracorporeal Membrane Oxygenation

Energy Transmission in Mechanically Ventilated Children

Mechanical energy (ME) better related to underlying lung pathology and patient outcome than MP. The delivery of generated energy to the lung was not dependent on endotracheal tube diameter (ETT) size during PC ventilation.... read more

Energy Transmission in Mechanically Ventilated Children

Ventilator Modes Made Easy: An Easy Reference for RRT’s, RN’s, and Medical Residents

Who says understanding ventilator modes has to be hard? This book gives you easy to understand information that every RRT, RN, or Resident always wishes they had. Each mode is described in simple language and answers the... read more

Ventilator Modes Made Easy: An Easy Reference for RRT’s, RN’s, and Medical Residents

Mechanical Ventilation Promotes Lung Tumor Spread by Modulation of Cholesterol Cell Content

Mechanical stretch of cancer cells can alter their invasiveness. During mechanical ventilation, lungs may be exposed to an increased amount of stretch, but the consequences on lung tumors have not been explored. To characterize... read more

Mechanical Ventilation Promotes Lung Tumor Spread by Modulation of Cholesterol Cell Content

Prognostic and Predictive Biomarkers in COVID-19 Patients Treated with Tocilizumab

Multiple biomarkers prognostic for clinical outcomes were confirmed in COVACTA. Ferritin was identified as a predictive biomarker for the effects of tocilizumab in the COVACTA patient population; high ferritin levels were... read more

Prognostic and Predictive Biomarkers in COVID-19 Patients Treated with Tocilizumab