This recently released practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the ICU. Readers will find... read more

Norepinephrine (NE) is both an alpha1- and beta1-agonist, and is therefore able to increase vascular tone and contractility. Recent guidelines recommend NE as the first-line vasopressor in septic shock.... read more

Nurses handle supplementary oxygen to intensive care unit (ICU) patients as part of their daily practice. To secure patients of optimal and safe care, knowledge of nurses’ perception of this practice,... read more

As with anything in medical field, there are so many resources that it is difficult and time consuming to determine which ones are the most valuable and worth reading. Therefore, we decided to compile... read more

Manual of ICU Procedures is a comprehensive, step-by-step guide to intensive care procedures. The book is divided into four anatomical sections, and a final miscellaneous section. Section one covers airway... read more

Early enteral nutrition (EEN), typically started within 48 h after ICU admission, is recommended to be superior over delayed enteral nutrition and parenteral nutrition. The ESICM Working Group on Gastrointestinal... read more

This NEW book is meant to be a reference for both the new and experienced point of care sonographer; to be a pocket guide to carry with you during your shift. We have included our best tips, tricks and... read more

Although there are limited studies investigating the safety and efficacy of an intermittent rather than continuous feeding regimen in critically ill adults, there are several theoretical advantages. Further... read more

This book discusses mechanical ventilation in emergency settings, covering the management of patients from the time of intubation until transfer to the ICU. It provides an introduction to key concepts... read more

As expected, higher levels of BLS training correlated with better cardiopulmonary resuscitation (CPR) quality. However, this study showed that ventilations and hands-on time were the components of CPR... read more

Until modifications in chimeric antigen receptor T-cell therapy decrease their toxicities, the intensivist will play a leading role in the management of critically ill chimeric antigen receptor T-cell... read more

A number of different models of peer support are currently being developed to help patients and families recover and grow in the post-critical care setting. Via an iterative process of in-person and email/conference... read more

A short course of intravenous vitamin C in pharmacological dose seems a promising, well tolerated, and cheap adjuvant therapy to modulate the overwhelming oxidative stress in severe sepsis, trauma, and... read more

Lower respiratory tract infections (LRTIs) are the leading cause of infectious disease-related deaths worldwide yet remain challenging to diagnose because of limitations in existing microbiologic tests.... read more

Music intervention has been shown to reduce anxiety and sedative exposure among mechanically ventilated patients. The aim of this study was to examine ICU costs for patients receiving a patient-directed... read more

Resuscitated cardiac arrest is associated with high mortality; however, the ability to estimate risk of adverse outcomes using existing illness severity scores is limited. Using in-hospital data available... read more

Acute respiratory distress syndrome (ARDS) results in substantial mortality but remains underdiagnosed in clinical practice. For this reason, automated “sniffer” systems that analyse electronic... read more

Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is commonly... read more

Levosimendan has been demonstrated to have potential utility in a range of critical illness scenarios. It must be acknowledged, however, that in each sphere of application, the evidence is incomplete or... read more

We read with great interest the recent letter to Critical Care by Marik and Hooper. Vitamin C is increasingly recognized as a crucial compound to alleviate morbidity in critically ill patients. Vitamin... read more

Hospital mortality in acute respiratory distress syndrome (ARDS) is approximately 40%, but mortality and trajectory in “mild” acute respiratory distress syndrome (classified only since 2012)... read more

When we talk about triage, we could mean several things. We might mean the triage of patients arriving in the ED to assign clinical priority (because not everyone can be seen instantly); we might mean... read more