Plasma Exchange in Critically Ill COVID-19 Patients
The spectrum of coronavirus disease 2019 (COVID-19) ranges from asymptomatic infection to respiratory failure and death of patients. Severely affected patients may develop a cytokine storm-like clinical syndrome with multi-organ... read more
Validation of a Point-of-Care Capillary Lactate Measuring Device
Lactate Pro 2 had good agreement with the reference method using arterial blood but poorer agreement using venous blood. Our results show the potential for overestimation of the lactate values in haemodynamically compromised... read more
Prone Positioning in Non-intubated Patients with COVID-19
As the COVID-19 pandemic has put severe stress and strain on the capacity of hospitals around the world, concerted efforts have been made to evaluate therapeutics aimed at preventing the need for mechanical ventilation. The... read more
Timing of Endoscopy for Acute Upper Gastrointestinal Bleeding
In patients with high risk upper GI bleeding, who were treated with pre-endoscopy PPI and were not in persistent shock, an endoscopy performed at a median of 10 hours vs. a median of 25 hours post presentation did not reduce... read more
ICU Capacity is More About the Clinicians Than The Number of Beds
Each time communities experience surges of COVID-19, concerns arise over the availability of hospital and intensive care unit beds in affected regions. To monitor ICU capacity, several states have begun to track and publicly... read more
Impact of Cardiovascular Risk Profile on COVID-19 Outcome
This study investigates the extent of cardiac comorbidities and complications among hospitalized patients with COVID-19. Cardiovascular complications are frequent among COVID-19 patients, and might contribute to adverse... read more
Post-Hospital VTE in Patients with COVID-19
The authors concluded that the rate of post-hospital venous thromboembolism (VTE) among patients with COVID-19 is low and that routine post-hospital prophylaxis is not necessary. Of the 1,877 hospital admissions with COVID-19... read more
Safety and Feasibility of Early Physical Therapy for Patients on ECMO
With a highly trained multidisciplinary team and a focus on restoring function, it is feasible and safe to deliver early rehabilitation including standing and ambulation to patients on extracorporeal membrane oxygenation... read more
Philips Launches COVID-19 Rapid Equipment Deployment Kit for ICUs
Royal Philips introduced its Rapid Equipment Deployment Kit for ICU ramp-ups, allowing doctors, nurses, technicians and hospital staff to quickly support critical care patient monitoring capabilities during the COVID-19 pandemic.... read more
A Randomised Trial of High-flow Nasal Cannula in Infants with Moderate Bronchiolitis
In patients with moderate bronchiolitis, there was no evidence of lower rate of escalating respiratory support among those receiving HFNC therapy. The analyses included 268 patients among the 2621 infants assessed for... read more
Right Heart Thrombus in Transit Diagnosed With Focused Cardiac Ultrasound
Pulmonary embolism (PE) is a potentially fatal entity that is frequently diagnosed in the emergency department (ED). Emergency physicians (EPs) routinely perform focused cardiac ultrasound (FOCUS) to support a prompt ED diagnosis... read more
Which One is Better? Chlorhexidine-impregnated Sponge or Chlorhexidine Gel Dressing
A similar infection risk for gel-dress and sponge-dress. Gel-dress showed fewer dressing disruptions. Concomitant use of CHG for skin disinfection and CHG-impregnated dressing may significantly increase contact dermatitis. A... read more
Laboratory Features of Severe vs. Non-severe COVID-19 Patients in Asian Populations
This meta-analysis provides evidence for the differentiation of severe cases of COVID-19 based on laboratory test results at the time of ICU admission. Future well-methodologically designed studies from other populations... read more
Fit-testing of N95/P2-masks to Protect Healthcare Workers
In the context of COVID-19, well fitted respirators e.g. N95/P2-masks are recommended as part of personal protective equipment when performing aerosol generating procedures. Fit-checking is recommended prior to donning... read more
Acute on Chronic Liver Failure in the ICU
Liver Failure may constitute one of the least favorite disease processes for anyone routinely taking care of critically ill patients. Intensivist and hepatology circles have begun to describe a specific population known as... read more
ICU Trends for Patients with COVID-19 in England, Wales and Northern Ireland
Observed trends suggest opposing effects of ICU strain and clinical learning. Further investigation is needed to identify modifiable system factors that could alleviate strain in future epidemics and changes in clinical practice... read more
The Night in the ICU
They say that in the world of the intensive care unit (ICU), there is no night. It can be qualified as a lesser day, but not really as a night. The hustle and bustle may be slower, patient flow and activity may be less, conversations... read more
Efficacy and Safety of a Paired Sedation and Ventilator Weaning Protocol in ICU
Approaches to removal of sedation and mechanical ventilation for critically ill patients vary widely. Our aim was to assess a protocol that paired spontaneous awakening trials (SATs)—ie, daily interruption of sedatives—with... read more
Pulmonary Embolism in COVID-19 Patients in France
Pulmonary embolism (PE) in the context of coronavirus disease 2019 (COVID-19) appears to be driven largely by inflammation and coagulopathy rather than by traditional risk factors for thromboembolism. Study results suggest... read more
Automated vs. Conventional Ventilation in the ICU
Automated ventilation (AV) appears to reduce the incidence and severity of blood oxygen desaturation during daily nursing procedures (DNPs) in comparison to Conventional Ventilation (CV). Of the 265 included patients,... read more
Pediatric Critical Care and COVID-19
We provide early clinical and laboratory data about critical pediatric COVID-19, which suggest a variable disease but generally good outcomes compared with adults. Targets for research include the course of organ failure... read more
Non-Invasive Cardiac Imaging for LVAD and OHT During COVID-19
Considerations for cardiac imaging in the COVID-19 era include thoughtful patient and study selection with a goal to limit the overall number of tests. General recommendations are as follows: Defer routine or low-risk... read more
