Dottoressa: An American Doctor in Rome

After completing her medical training in New York, Susan Levenstein set off for a one year adventure in Rome. Forty years later, she is still practicing medicine in the Eternal City. In Dottoressa: An American Doctor... read more

Dottoressa: An American Doctor in Rome

In-line Filtration of Intravenous Infusion May Reduce Organ Dysfunction of Adult Critical Patients

In-line filtration with finer 0.2 and 1.2 μm filters may be associated with less organ dysfunction and less inflammation in critically ill adult patients. Comparing fine filter vs control filter cohort, respiratory... read more

That Good Night: Life and Medicine in the Eleventh Hour

As the American born daughter of immigrants, Dr. Sunita Puri knew from a young age that the gulf between her parents' experiences and her own was impossible to bridge, save for two elements: medicine and spirituality. Between... read more

That Good Night: Life and Medicine in the Eleventh Hour

Outcomes of VV ECMO When Stratified by Age

The purpose of this study was to evaluate survival to hospital discharge for patients on venovenous extracorporeal membrane oxygenation (VV ECMO) when stratified by age. We performed a retrospective study at single, academic,... read more

Post-extubation Dysphagia

Despite having the tools and techniques for tracheal intubation for > 4000 years, and performing oral intubation with positive pressure mechanical ventilation for > 50 years, only recently has attention focused on... read more

Intensive Care Unit Telemedicine, An Issue of Critical Care Clinics

This issue of Critical Care Clinics, edited by Dr. Kianoush Kashani in collaboration with Consulting Editor Dr. John Kellum, is focused on Intensive Care Unit Telemedicine. Topics in this issue include: ICU telemedicine... read more

Intensive Care Unit Telemedicine, An Issue of Critical Care Clinics

FDA Approves New Pill to Treat Sickle Cell Disease

The Food and Drug Administration on Monday approved a once-daily pill for sickle cell disease that works in an entirely new way — by boosting hemoglobin, the oxygen-carrying molecule found in red blood cells. The novel... read more

When Brains Collide: What Every Athlete and Parent Should Know About the Prevention and Treatment of Concussions and Head Injuries

There is nearly a 20% chance that you or someone close to you will suffer a concussion this year. Whether they are in a car accident, fall off their bike, or suffer a helmet-to-helmet hit at football practice, over 30%... read more

When Brains Collide: What Every Athlete and Parent Should Know About the Prevention and Treatment of Concussions and Head Injuries

Adaptive Mechanical Ventilation with Automated Minimization of Mechanical Power

Adaptive mechanical ventilation with automated minimization of inspiratory power may lead to more lung-protective ventilator settings when compared with adaptive mechanical ventilation according to Otis' equation. Comparing... read more

Why Understanding Sepsis Endotypes Is Important for Steroid Trials in Septic Shock

Although corticosteroids clearly have beneficial effects on shock duration their impact on patient survival is less clear. The differences in mortality effects seen in past clinical trials could be explained by different... read more

An Ethical Claim for Providing Medical Recommendations in PICU

The Declaration of Geneva was recently revised to emphasize patient autonomy and the importance of clinicians sharing medical knowledge. This reflects the welcome evolution of the doctor-patient relationship from one... read more

Family Care Rituals in the ICU to Reduce Symptoms of PTSD in Family Members

Offering opportunities such as family care rituals for family members to be involved with providing care for family members in the ICU was associated with reduced symptoms of post-traumatic stress disorder (PTSD). This... read more

Corticosteroids as Adjunctive Therapy in the Treatment of Influenza

Corticosteroid treatment in influenza is associated with increased mortality and hospital-acquired infection, but the evidence relates mainly to high corticosteroid doses and is of low quality with potential confounding by... read more

Pulmonary Artery Catheters for Adult Patients in ICU

Pulmonary Artery Catheters (PAC) is a diagnostic and haemodynamic monitoring tool but not a therapeutic intervention. Our review concluded that use of a PAC did not alter the mortality, general ICU or hospital LOS, or cost... read more

Practical Trends in Anesthesia and Intensive Care 2018

This book offers an essential guide to managing the most-debated hot topics of practical interest in anesthesia and intensive care. It reviews the state of the art in issues concerning both intensive care medicine and anesthesia,... read more

Practical Trends in Anesthesia and Intensive Care 2018

Triage and Flow Management in Sepsis

Septic patients had a lower priority for ICU admission and longer waiting times for an ICU vacancy than patients with other critical conditions. Overall, this implied a 2.7-fold increased risk of mortality in septic patients. The... read more

Critical Care Doctors Placed Humans in Suspended Animation For The First Time

Critical care doctors have placed humans in suspended animation for the first time, as part of a trial in the US that aims to make it possible to fix traumatic injuries that would otherwise cause death. Samuel Tisherman,... read more

Left Ventricular Wall Findings in Non-electrocardiography-gated CE-CT After ECPR

Few studies have reported left ventricular wall findings in contrast-enhanced computed tomography (CE-CT) after extracorporeal cardiopulmonary resuscitation (ECPR). This study examined left ventricular wall CE-CT findings... read more

Serum Creatinine in the Critically Ill Patient With Sepsis

A 73-year-old man underwent esophageal resection for cancer. He had a history of hypertension that was treated with an angiotensin receptor blocker. Preoperative estimated glomerular filtration rate (GFR) was 98 mL/min/1.73... read more

Long-term Cognitive Impairment After ARDS

Reducing the practical burden of cognitive recovery following critical illness depends crucially on understanding the links between brain injury and lung injury. New deficits in learning and memory, and new development... read more

Complications in Acute Care Surgery: The Management of Difficult Clinical Scenarios

This text provides the reader a starting point for the most difficult and uncommon complications in acute care surgery. It is designed to provide options to that ubiquitous intra-operative or bedside question "Well, now what... read more

Complications in Acute Care Surgery: The Management of Difficult Clinical Scenarios

Low-flow Assessment of Current ECMO/ECCO2R Rotary Blood Pumps and the Potential Effect on Hemocompatibility

The role of blood pumps in contributing to adverse effects at the lower blood flow rates used during ECCO2R is shown here to be significant. Current rotary blood pumps should be used with caution if operated at blood... read more