Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury
Cardiac dysfunction (CD) importantly contributes to mortality in trauma patients, who survive their initial injuries following successful hemostatic resuscitation. This poor outcome has been correlated with elevated biomarkers... read more
Hyperchloremia Is Associated With AKI in Patients With Subarachnoid Hemorrhage
Critically ill patients with subarachnoid hemorrhage show a strong association between hyperchloremia and acute kidney injury as well as acute kidney injury and mortality. Of 1,267 patients included in this cohort, 16.7%... read more
Assessment of immune organ dysfunction in critical illness
Critical illness may often induce persisting injury-associated immunosuppression with adverse effects on relevant patient-centered outcomes. However, despite the key task of ICU physicians to detect, monitor, and follow up... read more
Predicting Adverse Hemodynamic Events in Critically Ill Patients
The art of predicting future hemodynamic instability in the critically ill has rapidly become a science with the advent of advanced analytical processed based on computer-driven machine learning techniques. How these... read more
The Protective Effects of Regional Hypothermia on Injured Limbs Combined with Hemorrhagic-shock & Tourniquet
The aim of this study is to investigate the protective effects of regional hypothermia (RH) on rabbits' limbs injured by a steel-ball combined with hemorrhagic-shock, and then employed tourniquet over-time, tried to identify... read more
Trauma Nursing: From Resuscitation Through Rehabilitation
Learn to provide state-of-the-art care to any patient in any setting with the most comprehensive trauma nursing resource available. Using the unique cycles of trauma framework, Trauma Nursing: From Resuscitation Through... read more
The Neurohormonal Basis of Pulmonary Hypertension in HFpEF
Subjects with heart failure with preserved ejection fraction (HFpEF) display activation of the endothelin and adrenomedullin neurohormonal pathways, the magnitude of which is associated with pulmonary hemodynamic derangements,... read more
Targeted Temperature Management at 33 vs. 36 Degrees
Comatose, adult out-of-hospital cardiac arrest patients treated during the targeted temperature management 33°C period had higher odds of neurologically intact survival to hospital discharge compared with those treated during... read more
First ICU Certified in Humanization (H-ICU)
250 ICUs around the world that have performed the self-assessment, the baseline compliance referred is between 40 and 60%. For more than a year, the team of the ICU of Valdemoro distributed the pending good practices and... read more
Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes
In this multicenter cohort, ventilation rates exceeding guidelines were common. Among the range of rates delivered, higher rates were associated with improved survival to hospital discharge. Arterial blood pressure and... read more
Nonoperative Management of Splenic Injury of Patients with Reduced Consciousness is Safe and Feasible in Well-equipped Institutions
This study shows that NOM for blunt splenic trauma is a viable treatment modality in well-equipped institutions, regardless of the patients mental status. However, the presence of neurologic impairment is associated with... read more
Distance Between the Tips of Central Venous Catheters Does Not Depend on Same or Opposite Site Access
Central venous catheters (CVCs) are routinely required in the intensive care unit (ICU) for infusion of drugs, often concurrently with central venous dialysis catheters (CVDCs) for renal replacement therapy (RRT). Increased... read more
Mechanical Ventilation in Patients with Acute Ischemic Stroke
Although there are no specific data regarding the effect of respiratory management on stroke patients' outcomes, specific ventilator strategies in this population could potentially improve neurologic outcome and prevent respiratory... read more
Ultrasound-based Clinical Profiles for Predicting the Risk of Intradialytic Hypotension in Critically Ill Patients on Intermittent Dialysis
In critically ill patients on intermittent hemodialysis, the absence of hypervolemia as assessed by lung and vena cava ultrasound predisposes to intradialytic hypotension and suggests alternative techniques of hemodialysis... read more
Pain Response to Open Label Placebo in Induced Acute Pain in Healthy Adult Males
Open label placebos might play a role in multimodal analgesic concepts. Pain ratings (median, first to third quartile) were 21% lower during placebo treatment compared to no treatment, 4.0 (3.2 to 4.9) versus 5.1 (4.7... read more
Economic Evaluation of a Patient-Directed Music Intervention for ICU Patients Receiving Mechanical Ventilatory Support
Music intervention has been shown to reduce anxiety and sedative exposure among mechanically ventilated patients. The aim of this study was to examine ICU costs for patients receiving a patient-directed music intervention... read more
An assessment of repeat computed tomography utilization in the emergency department in the setting of blunt trauma
Two CT scans performed during blunt trauma encounters demonstrated mixed benefit and were associated with an increased hospital LOS. Additionally, IV contrast was associated with lower rates of AKI. Of 5787 patient encounters,... read more
TAPSE Has Superior Predictive Value vs. RV/LV Ratio in Normotensive Patients with Acute Pulmonary Embolism
Right ventricular dysfunction (RVD) is an indicator of poor prognosis in normotensive patients with acute pulmonary embolism (APE). The aim of this study was to compare right ventricular (RV)/left ventricular (LV) ratio measured... read more
Nonconvulsive Status Epilepticus
The only comprehensive source of information on this frequently misdiagnosed problem, with information critical for physicians, ER and ICU doctors, and psychiatrists. An under-recognized condition that can potentially... read more
Nonconvulsive Status Epilepticus: Overlooked and Undertreated
Nonconvulsive status epilepticus (NCSE) is characterized by persistent change in mental status from baseline lasting more than 5 minutes, generally with epileptiform activity seen on EEG monitoring and subtle or no motor... read more
Preoperative Risk and the Association between Hypotension and Postoperative AKI
Adult patients undergoing noncardiac surgery demonstrate varying associations with distinct levels of hypotension when stratified by preoperative risk factors. Specific levels of absolute hypotension, but not relative... read more
Timing of Tracheostomy in Pediatric Patients
In children on mechanical ventilation, early tracheostomy may improve important medical outcomes. However, our data demonstrate the urgent need for high-quality, randomized controlled trials in the pediatric population. Data... read more
