Identification of Subclasses of Sepsis that Showed Different Clinical Outcomes and Responses to Amount of Fluid Resuscitation
Sepsis is a heterogeneous disease and identification of its subclasses may facilitate and optimize clinical management. This study aimed to identify subclasses of sepsis and its responses to different amounts of fluid resuscitation.... read more
How to Optimize the Use of Blood Cultures for the Diagnosis of Bloodstream Infections?
Bloodstream infection (BSI) is a major cause of death in developed countries and the detection of microorganisms is essential in managing patients. Despite major progress has been made to improve identification of microorganisms,... read more
Mechanical Ventilation Sedation Necessary for Comfort According to Nurses
Nurses' attitudes toward sedating patients receiving mechanical ventilation have shifted in the past decade, with fewer nurses now believing that all patients should be sedated. However, more than half of nurses still agree... read more
CDC Launches Investigation Into Surge Of Severe Lung Disease Cases Linked To Vaping
The federal Centers for Disease Control and Prevention (CDC) is investigating the sudden emergence of severe lung disease linked to vaping in 14 states. CDC is providing consultation to the departments of health in Wisconsin,... read more
Crisis Management in Acute Care Settings
Crisis Management in Acute Care Settings: Human Factors and Team Psychology in a High-Stakes Environment is unique in providing a comprehensive overview of the human factors issues relevant to patient safety during acute... read more
More Precise Sepsis Therapy with Distinct Clinical Phenotypes
In this retrospective analysis of data sets from patients with sepsis, 4 clinical phenotypes were identified that correlated with host-response patterns and clinical outcomes, and simulations suggested these phenotypes may... read more
Epidemiology of Sepsis and Septic Shock in Critical Care Units
A comparison between sepsis-2 and sepsis-3 populations using a national critical care database. In an ICU database, compared with Sepsis-2, Sepsis-3 identifies a similar sepsis population with 92% overlap and much smaller... read more
Impact on Patient Outcomes of Pharmacist Participation in Multidisciplinary Critical Care Teams
Including critical care pharmacists in the multidisciplinary ICU team improved patient outcomes including mortality, ICU length of stay in mixed ICUs, and preventable/non-preventable adverse drug events. From the 4,725... read more
A Compression Method to Reduce Fluid Balance of Septic Shock Patients
This article presents a close look at the Corporeal Compression at the Onset of Septic shock (COCOONs). Fluid overload in septic intensive care unit (ICU) patients is common and strongly associated with poor outcome. There... read more
Emergency Department Resuscitation of the Critically Ill
A crash course in Critical Care! Stabilize, treat, and save your sickest patients in the ed or the field – with ACEP's ultimate resuscitation guide. packed with succinct evidence-based chapters written by the nation's foremost... read more
Preventing Surgical Site Infections Related to Abdominal Drains in the ICU
Surgical site infections are significant contributors to health care–associated infections. Nursing interventions may help decrease the incidence of surgical site infections, particularly in regards to the management of... read more
Laryngeal Injury and Upper Airway Symptoms After Oral Endotracheal Intubation With Mechanical Ventilation During Critical Care
Laryngeal injury from intubation is common in the ICU setting. Guidelines for laryngeal assessment and postextubation surveillance do not exist. A systematic approach to more robust investigations could increase knowledge... read more
Antipsychotics to Treat Delirium in Hospitalized Patients Not Including the ICUs
No evidence has been found to support or refute the suggestion that antipsychotics shorten the course of delirium in hospitalized patients. Based on the available studies, antipsychotics do not reduce the severity of delirium... read more
Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium
Prophylactic haloperidol use does not affect long-term quality of life in critically ill patients at high risk for delirium. Several factors, including the modifiable factor number of sedation-induced coma days, are associated... read more
Sedation Practices of Neonates Receiving ECMO
Neonatal sedation practices during extracorporeal membrane oxygenation (ECMO) are not well described and no universal guidelines exist. Current literature describes types of medications used in adult and pediatric ECMO... read more
Pulmonary Embolism Hospitalization, Readmission, and Mortality Rates in US Older Adults
Over the past 15 years, advances have occurred in the diagnosis and management of pulmonary embolism (PE).1 Computed tomographic pulmonary angiography (CTPA) is now the routine diagnostic test. The availability of risk... read more
Randomized Clinical Trial of an ICU Recovery Pilot Program for Survivors of Critical Illness
This randomized pilot trial found that a multidisciplinary ICU recovery program could deliver more interventions for post ICU recovery than usual care. The finding of longer time-to-readmission with an ICU recovery program... read more
Outcome After Out-of-Hospital Ventricular Fibrillation or Pulseless Ventricular Tachycardia
Survival was found to be at the upper range of the results retrieved by the systematic literature review. However, we found no significant improvements over time. The neurological outcomes of the survivors were favorable.... read more
Estimated Effects of Early Diuretic Use in Critical Illness
The main objectives of this study was to estimate the effects of diuretic use during the first 24 hours of an ICU stay on in-hospital mortality and other clinical outcomes including acute kidney injury (AKI) and duration... read more
The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill
Transfusion of red blood cells is an everyday practice in critical care with the primary aim of restoring adequate tissue oxygenation. However, blood transfusion may also be harmful and costly, therefore a so called restrictive... read more
Department-Based ICU Improves Patient Survival Rates
A new Michigan Medicine study found that implementing a dedicated emergency medicine department-based intensive care unit improved patient survival rates and lowered inpatient intensive care unit (ICU) admissions. In the... read more
12 Great Summer Reads for Intensivists
From fascinating medical memoirs to horrifying accounts of medical mistreatment in the past two centuries, these books will make you aware of how far medicine has come and how far it has yet to go. Surgeries without anesthesia,... read more
