Management of Cardiogenic Shock
Cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction although mortality could be reduced from formerly ∼80% to 40–50%. In addition to percutaneous coronary intervention... read more
Hemodynamic Impact of Oxygen Desaturation During Tracheal Intubation Among Critically Ill Children With Cyanotic and Noncyanotic Heart Disease
Oxygen desaturation was more commonly observed during tracheal intubation in children with cyanotic versus noncyanotic heart disease. However, hemodynamic tracheal intubation associated event rates were similar. In both groups,... read more
Risk of Sepsis and Mortality Among Patients with COPD Treated With Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers
Angiotensin receptor blockers were associated with lower rates of sepsis and mortality than angiotensin-converting enzyme inhibitors in the patients with chronic obstructive pulmonary disease. The similar findings were also... read more
Early Goal-directed Therapy Using a Physiological Holistic View
If peripheral perfusion-targeted resuscitation improves 28-day mortality, this could lead to simplified algorithms, assessing almost in real-time the reperfusion process, and pursuing more physiologically sound objectives.... read more
Ultrasound for Lung Monitoring of Ventilated Patients
In the intensive care unit, patient lung ultrasound provides accurate information on lung morphology with diagnostic and therapeutic relevance. It enables clinicians easy, rapid, and reliable evaluation of lung aeration and... read more
Podcast Use and Preferred Content Among Residents
This study is the first to report podcast content needs and preferred formats among specialty trainees. Anesthesia residents appear to have well defined podcast content preferences. In addition, senior and junior anesthesia... read more
Association of an Emergency Department–Based ICU With Survival and Inpatient ICU Admissions
The purpose of this study is to determine the association of a novel ED-based ICU, the Emergency Critical Care Center (EC3), with 30-day mortality and inpatient ICU admission. In this cohort study of 349,310 patient encounters... read more
A Core Outcome Set for Critical Care Ventilation Trials
The main objective for this study was to obtain international consensus on a set of core outcome measures that should be recorded in all clinical trials of interventions intended to modify the duration of ventilation for... read more
Essentials of Mechanical Ventilation
The acclaimed application-based guide to adult mechanical ventilation, updated to reflect the latest topics and practice guidelines. This practical guide is written from the perspective of authors who have nearly 100 years'... read more
Droperidol Use in the Emergency Department – What’s Old is New Again
Earlier this year American Reagent announced the re-introduction of droperidol back into the US market. This is bringing an old favorite back to many EM docs and a novel tool for new residents and attendings who have never... read more
Does Head of Bed Elevation During Intubation Improve Patient Oriented Outcomes?
To date the study that has shown the biggest benefit to HOB elevation is the 2016 study performed by Khandelwal and colleagues in a teaching hospital system in Seattle, WA. 528 patients managed by anesthesiologists... read more
Reduced Level of Arousal on Hospital Admission
Reduced level of arousal on hospital admission may be a strong predictor of in-hospital mortality. Most evidence was of low quality. Reduced level of arousal is highly specific to delirium, better formal detection of hypoactive... read more
How Best to Set the Ventilator on Extracorporeal Membrane Lung Oxygenation
Mechanical ventilation and extracorporeal support are marginally integrated. The best environment for lung healing – complete lung collapse or protective ventilation strategy or fully open and immobile lung (all three conditions... read more
Stress Ulcer Prophylaxis with Proton Pump Inhibitors or Histamin-2 Receptor Antagonists in Adult Intensive Care Patients
In this updated systematic review, we were able to refute a relative change of 20% of mortality. The occurrence of GI bleeding was reduced, but we lack firm evidence for a reduction in clinically important GI bleeding. The... read more
Effective Goal-Directed Therapy in TBI Patients May Improve Outcomes
The purpose of this study was to estimate the impact of goal-directed therapy on outcome after traumatic brain injury (TBI). Goal-directed therapy was applied to standardize care in patients with moderate to severe traumatic... read more
Measuring Cardiac Output at the Bedside
The purpose of this review is to review the importance of cardiac output (CO) or stroke volume (SV) measurement and to discuss the various methods (devices) used in determination of CO. Bedside cardiac output measurement... read more
Resuscitation Guided by Volume Responsiveness Does Not Reduce Mortality in Sepsis
The results of this systematic review and meta-analysis indicate that a volume responsiveness (VR) guided resuscitation strategy in sepsis patients confers no mortality benefit compared with usual care. The methods of... read more
Core Outcome Measures for Critical Care Ventilation Trials
The main objective for this study was to obtain international consensus on a set of core outcome measures that should be recorded in all clinical trials of interventions intended to modify the duration of ventilation for... read more
TPTD Techniques in the Hemodynamically Unstable Patient
Transpulmonary thermodilution (TPTD) devices invasively measure not only cardiac output but also several other hemodynamic variables estimating cardiac preload, cardiac preload, systolic function, the lung oedema and systolic... read more
Systematic Reviews and Meta-Analyses in Critical Care Research
This webinar provides an overview of the key steps involved in systematic reviews and meta-analysis for those interested in using these approaches in their own research. As the volume of published research in critical... read more
Risk Factors for Avoidable Transfer to a Pediatric Trauma Center Among Patients Age Two Years and Older
Among injured children age two years and older, those with minor head injuries were at greatest risk for avoidable transfer. Many were transferred because of a perceived need for evaluation by a pediatric neurosurgeon. Future... read more
Worse outcomes with video laryngoscopy in ICU
When used in intensive care units, video laryngoscopy did not improve the chances of successful intubation on the first try, compared with direct laryngoscopy, and was associated with a significantly higher risk of severe... read more
