Essentials of Neuroanesthesia and Neurointensive Care

This updated second edition of Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care contains the ideal combination of updated information for the practitioner, presented in easy-to-digest short chapters.... read more

Essentials of Neuroanesthesia and Neurointensive Care

Pharmacotherapy in Neurointensive Care

Neurointensive care medicine has experienced great advancements and developments of neuromonitoring techniques, allowing a better comprehension of acute brain injury early phase pathological mechanisms and an overall improvement... read more

Developmentally Appropriate Coping in the ICU

In this video, Child Life Specialist at Boston Children's Hospital, Kate Huyler, outlines the role of a child life specialist, reviews coping strategies for patients in the ICU, including the use of playtime and behavioral... read more

Manual of Traumatic Brain Injury: Assessment and Management

Now completely revised and updated, Manual of Traumatic Brain Injury: Assessment and Management, Second Edition is a comprehensive evidence-based guide to brain injury diagnosis, treatment, and recovery, delivered in a succinct... read more

Manual of Traumatic Brain Injury: Assessment and Management

Practical Management of Invasive Candidiasis in Critically Ill Patients

The heterogeneity of this patient population necessitated the creation of a mixed working group comprising experts in clinical microbiology, infectious diseases and intensive care medicine, all chosen on the basis of their... read more

Sepsis Sub-phenotypes by Temperature Trajectories

In this "Breathe Easy Critical Perspective" podcast, Dr. Dominique Pepper interviews Dr. Siva Bhavani. They discuss sepsis sub-phenotypes by temperature trajectories. Dr. Bhavani is a senior fellow in Pulmonary and Critical... read more

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery

Intravenous lidocaine administered during and after cardiac surgery did not reduce postoperative cognitive decline at 6 weeks. Among the 420 allocated subjects who returned for 6-week follow-up, there was no difference in... read more

Sustained reduction of catheter-associated bloodstream infections with enhancement of catheter bundle by chlorhexidine dressings over 11 years

The addition of chlorhexidine dressings to all CVC and arterial lines to an ongoing catheter bundle was associated with a sustained 11-year reduction of all catheter-associated bloodstream infections. This large real-world... read more

Gut Dysmotility in the ICU

Off-label metoclopramide and/or erythromycin administration are effective for upper gastrointestinal dysmotility but have adverse effects. Trials of alternative or novel promotility drugs have not demonstrated superiority... read more

How and Whom to Monitor for Seizures in an ICU

Prevalence of seizures detected by continuous electroencephalography was significantly higher than with routine electroencephalography. Prevalence was particularly high in post convulsive status epilepticus, CNS infection,... read more

I am a male nurse – so what?

For Brett Adamson, becoming a nurse was a gateway into helping the world’s most disadvantaged people. In 2005 Brett began working for the medical humanitarian aid organisation, Médecins Sans Frontières. That year was... read more

The Glutamine Debate in Surgery and Critical Care

Three recent meta-analyses have confirmed traditional glutamine (GLN)-supplemented (or "GLN-Complemented" – providing GLN for completeness of amino acid content) TPN is safe, reduces mortality and improves outcome in surgical... read more

Prevalence and outcome of heparin-induced thrombocytopenia diagnosed under veno-arterial extracorporeal membrane oxygenation

Prevalence of HIT among patients under VA‑ECMO is extremely low at 0.36% with an associated mortality rate of 33.3%, which appears to be in the same range as that observed in patients treated with VA‑ECMO without HIT.... read more

Thiamine Deficiency: Pearls and Pitfalls

Although thiamine would not be isolated until 1911, the clinical syndrome of thiamine deficiency was recognized as far back as 2700 BC, when the term "beriberi", meaning "wasted wasted" was first coined in China. Nearly 5,000... read more

Long-Term Outcome after Prolonged Mechanical Ventilation

Among patients receiving prolonged mechanical ventilation at an LTACH, 53.7% were detached from the ventilator at discharge and 1-year survival was 66.9%. Respiratory strength was well maintained, whereas peripheral strength... read more

Prediction and Management of Severe Acute Pancreatitis

This volume provides a comprehensive summary of the field, with expert recommendations on prediction and management. It details the recent consensus guidelines (2012) updating the definition of pancreatitis and its complications.... read more

Prediction and Management of Severe Acute Pancreatitis

How to Deal with Severe Acute Pancreatitis in the Critically Ill

Management of severe acute pancreatitis (SAP) is multimodal with emphasis on monitoring, adequate fluid resuscitation, avoiding prophylactic use of antibiotics, cause-directed procedures or treatment, and organ support. There... read more

Study of the Effects of Epinephrine on Cerebral Oxygenation and Metabolism During Cardiac Arrest and Resuscitation by Hyperspectral Near-Infrared Spectroscopy

Epinephrine administration by bolus resulted in transient improvements in cerebral oxygenation and metabolism, whereas continuous epinephrine infusion did not, compared with placebo. Future studies are needed to evaluate... read more

Oxygen Use, Lower Lung Function Seen as Predictors of Death or Transplant in IPF

The use of oxygen at rest is associated with a greater likelihood of death or lung transplant in people with idiopathic pulmonary fibrosis (IPF), a study shows. The results also showed that lower lung function at the start... read more

Defining Sepsis on the Wards

The aim of this study is to look at the prevalence (commonness) of sepsis across acute hospitals (hospitals with an emergency department) across Wales using the currently used and new definitions of sepsis. Sepsis is a major... read more

Ketamine Sedation for Patients With Acute Behavioral Disturbance During Aeromedical Retrieval

Acute behavioural disturbance(ABD), also known as Excited Delirium Syndrome, is a medical emergency with reported mortality of 8-10%. The management of ABD usually involves a judicious combination of de-escalation techniques,... read more

Psychological and Cognitive Impact of Critical Illness

Hot off the presses. Concise book on PICS, PICS-F and FICUS. Neuropsychiatric problems after critical illness are receiving increasing attention, particularly in the critical care medicine literature, but mental health and... read more

Psychological and Cognitive Impact of Critical Illness