Combined Data Show Superiority of LAMA/LABA in COPD
Patients with chronic obstructive pulmonary disease (COPD) experienced significantly fewer acute exacerbations when a long-acting muscarinic antagonist (LAMA) was added to a long-acting beta agonist (LABA) than when an inhaled... read more
New Cytokine Approach is Synergistic With Checkpoint Inhibitors
Among the new agents currently being explored in clinical trials, NKTR-214 stands out as a new cytokine therapy approach that could show additive benefit when combined with checkpoint inhibitors. ... read more
Stem cell transplant in primates treats injured hearts
After undergoing a transient myocardial infarction (MI), primates injected with stem cells showed improved heart function.... read more
Wearable, Skin-Mounted Stethoscope Monitors Heartbeat
A new type of acoustic sensor that resembles a small Band-Aid on the skin can monitor heartbeat and other health measures.... read more
Fatty Acid Levels Could Help Predict Psychosis Risk
A novel probabilistic model that combines history, clinical assessment, and fatty-acid biomarkers could help predict transition to first-episode psychosis.... read more
Nonadherence to Meds Hurts NSTEMI Patients, Especially After PCI
Patients who were revascularized for a non-ST-segment elevation myocardial infarction (NSTEMI) did better if they adhered to their medications.... read more
Low Blood Glucose Levels In Hospitalized Patients Linked To Increased Mortality Risk
Mortality risk was higher in insulin-treated patients with moderate hypoglycemia (40-70 mg/dL), compared to patients without insulin treatment with similar glucose values.... read more
CDC estimates preventable deaths from 5 leading causes
The federal Centers for Disease Control and Prevention released data naming the five leading causes of death among Americans under age 80 for 2014.... read more
Data from clinical registries can ID novel drug interactions
Data mining can be used to discover unknown drug-drug interactions in cardiovascular medicine, according to a study published online Nov. 8 in Circulation: Cardiovascular Quality and Outcomes.... read more
SCCM Pod-330 Long-Term Mental Health Problems After Delirium in the ICU
Todd Fraser, MD, speaks with Arjen Slooter, MD, PhD, about the article, "Long-Term Mental Health Problems After Delirium in the ICU," published in Critical Care Medicine.... read more
Sepsis on the Wards Manuscript Available Open Access
Surviving Sepsis Campaign supporter, the Gordon and Betty Moore Foundation, recently funded open access with its Sepsis on the Wards grant for original research.... read more
One-Third of Hypertension Patients Noncompliant with Therapy
More than 30% of patients with hypertension do not adhere to their antihypertensive drug therapy, according to a new study.... read more
Smartwatches connect intensive care doctors and their patients
Researchers have come up with a way to link a smartwatch to the metabolic monitors used with patients in intensive care. If the sensors detect an anomaly, the doctor on duty receives an alert anywhere in the hospital.... read more
Could a Metabolic Switch Explain Inflammation in Lupus Patients?
Researchers discovered a new mechanism linking specific classes of immune cells and metabolism, a finding that may explain why patients with lupus are incapable of controlling the inflammatory responses that ultimately lead... read more
Plasma cytokine levels predict response to corticosteroids in septic shock
Plasma concentration of selected cytokines is a potential predictive biomarker to identify septic shock patients that may benefit from treatment with corticosteroids.... read more
FDA Approves Defibrillator That Automatically Adjusts Pacing
The FDA has cleared the Claria MRI Quad Cardiac Resynchronization Therapy Defibrillator (CRT-D) SureScan device (Medtronic) for patients with heart failure.... read more
Cricoid Pressure at Lower Forces Does Not Increase Oxygen Consumption
A pilot study has found that patients randomly assigned to cricoid pressure or sham treatment showed no difference in time to lowest peripheral capillary oxygen saturation (SpO2) or lowest SpO2 during anesthesia induction... read more
Bariatric surgery may protect against heart failure
Bariatric surgery appears to reduce substantially the risk of heart failure.... read more
Bacteriophages cure bacterial infections
Phage therapy may be a solution to treating infections caused by antibiotic-resistant bacteria. Since 2013, researchers at the University of Helsinki in Finland have collected bacteriophages to combat antibiotic-resistant... read more
New Clinical Resources From American Association Of Critical-Care Nurses Address Delirium, CAUTI And VTE
Updated AACN Practice Alerts offer latest evidence-based practice related to delirium, catheter-associated urinary tract infections and venous thromboembolism.... read more
Impella CP Versus Intra-Aortic Balloon Pump in Acute Myocardial Infarction Complicated by Cardiogenic Shock
At 30 days, mortality in patients treated with either IABP or Impella CP was similar (50% and 46%, respectively, hazard ratio (HR) with Impella CP, 0.96 (95% confidence interval (CI) 0.42 to 2.18; p=0.92).... read more
The impact of extracerebral organ failure on outcome of patients after cardiac arrest
In this multicenter cohort, extracerebral organ dysfunction was common in CA patients. Renal failure on admission was the only extracerebral organ dysfunction independently associated with higher ICU mortality.... read more
