POCT for emergency assessment of coagulation in patients treated with direct oral anticoagulants
Hemochron Signature Point-of-care testing (POCT) can be a fast and reliable alternative for guiding emergency treatment during rivaroxaban and dabigatran therapy. It allows the rapid identification of a relevant fraction... read more
Hemolytic Uremic Syndrome (HUS): Pearls and Pitfalls
A three-year-old male presents with mom for seven days of fever, diarrhea, and decreased activity. When you walk into the room, you note a listless-appearing boy with pallor. His eyes appear sunken. He is tachycardic, tachypneic,... read more
Wide variations found in evaluation of newborns for sepsis
The evaluation of well-appearing term infants for early-onset sepsis (EOS) varies considerably among hospitals, with some doing extensive work-ups and giving antibiotics while others simply observe and provide newborn routine... read more
Intravenous Lidocaine To Reduce Propofol Burning And Response To Laryngoscopy
Lidocaine (1 - 1.5 mg/kg) is often given intravenously prior to the induction of general anesthesia for a dual purpose - to mitigate the burning sensation of propofol (attributed to its glycerol additive) and to blunt the... read more
MR-proADM Accuracy Superior for Sepsis Mortality Prediction
The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin... read more
Carotid Stenting Technology Has More Appeal
Ten-year follow-up from the CREST trial and 5-year follow-up from the ACT I study, presented at least year's International Stroke Conference, showed that carotid artery stenting (CAS) holds up well over the long term... read more
Candida Auris forms biofilms that enhance its virulence and resistance
In three separate trials, eight samples of each strain of C. auris grew biofilms that constitute a key driver of Candida pathogenicity. C. auris first attracted attention in 2009 because of its resistance to azoles and amphotericin... read more
Clinical practice guideline on diagnosis and treatment of hyponatraemia
Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms,... read more
Sepsis Readmissions Compared With Other Medical Conditions
This study uses data from a US readmissions database to assess whether sepsis hospitalizations account for a higher proportion of unplanned 30-day readmissions than hospitalizations for acute myocardial infarction, heart... read more
CHS using virtual critical care for heart patients
It just might be the future of medicine. Using cameras, microphones and medical sensors, heart surgeons and cardiologists inside the Sanger Heart & Vascular Institute at Carolinas HealthCare System are treating patients... read more
NIH $3.2 million Grant Funds Mobile Critical Care Recovery Program
Two million of the five million Americans admitted to intensive care units annually have or develop acute respiratory failure, predisposing them to long-term cognitive, functional and psychological impairments collectively... read more
Blood Thinner Also Effective for Artery Disease
A phase 3 trial evaluating the efficacy and safety of rivaroxaban (Xarelto, Bayer/Janssen), an oral anticoagulant, for the prevention of major adverse cardiac events (MACE) - including cardiovascular death, myocardial infarction,... read more
Ureteral stents, sepsis and acute kidney injury: Iatrogenic imperfecta!
Case presentation A 62-year-old woman with a past history of placement of bilateral ureteral "JJ" stents, presented to the hospital complaining of fever, chills, abdominal pain, oliguria and was found to be hypotensive.... read more
Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI
Except for urinary pH, none of the outcomes differed between the two groups. Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated... read more
How survival of cancer patients in critical care has improved in the last 3 decades
Comprehensive care for critically ill patients with cancer is a collaborative effort, and close cooperation between oncology as well as palliative and critical care is essential. Collaborative decision making is a cornerstone... read more
Thrombocytosis in the ED
Both reactive thrombocytosis and clonal thrombocytosis may be associated with vasomotor symptoms. The key difference is that thrombotic and bleeding events are much more common in myeloproliferative thrombocytosis, whereas... read more
Central Line Versus Peripheral IV Flow Rates In Resuscitation
The indications for central venous catheters (CVCs) include invasive hemodynamic monitoring, transvenous cardiac pacing, hemodialysis, lack of peripheral venous access, administration of vasopressors, nutritional support,... read more
Portable Imaging Device Assesses Tissue Oxygenation
A handheld, battery operated diagnostic imaging device measures oxygen saturation (O2Sat) and other measures in superficial tissues for patients with potential circulatory compromise. The HyperView is intended for use by... read more
Interventions to improve antibiotic prescribing practices for hospital inpatients
This review includes 221 studies (58 RCTs, and 163 NRS). Most studies were from North America (96) or Europe (87). The remaining studies were from Asia (19), South America (8), Australia (8), and the East Asia (3). We found... read more
Catheter System Drains Recurrent Pleural Effusions
A novel catheter system enables patients to drain pleural fluid at home, instead of requiring them to return to the hospital for thoracentesis. The PleurX catheter system consists of a catheter that is inserted in the chest... read more
Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock
Three distinct models for reporting risk-adjusted mortality rates among hospitals and physicians performing PCI in New York State demonstrate a high degree of agreement, despite variation in how they handle the inclusion... read more
Crizanlizumab use lowers rates of sickle cell crises
Patients with sickle cell disease treated with high-dose crizanlizumab experienced lower annualized rates of sickle cell crisis compared to placebo treatment, regardless of their baseline use of hydroxyurea. Those treated... read more
