Restricting volumes of resuscitation fluid in adults with septic shock after initial management
A protocol restricting resuscitation fluid successfully reduced volumes of resuscitation fluid compared with a standard care protocol in adult ICU patients with septic shock.... read more
The Association of Early Combined Lactate and Glucose Levels with Subsequent Renal and Liver Dysfunction
Abnormal combined lactate and glucose measurements may provide an early indication of organ dysfunction. In critically ill patients a 'normal' glucose with an elevated lactate should not be considered desirable, as this combination... read more
Standardize ICU Admission Practices to Cut Costs
Hospitals that admitted patients to ICUs more often were more likely to routinely perform invasive procedures and incur higher costs with no commensurate improvement in mortality.... read more
Hospitals with most heart patients in ICU have worse results: Study
Heart attack or heart failure patients are more likely to get worse or die at hospitals that are more likely to treat them in the ICU, a new study suggests.... read more
Glycemic control, mortality, and hypoglycemia in critically ill patients
Network meta-analysis showed no mortality benefit of tight glycemic control in critically ill patients, but fivefold more hypoglycemia versus mild or very mild control. Thirty-six randomized trials (17,996 patients) were... read more
Don’t Just Do Something, Stand There!
An excellent analogy on how doing nothing can be the best option. Penalty kicks in soccer can make fans crumple with anguish or weep with elation. The kicker sends the ball rocketing toward the goal and goalkeepers lunge... read more
Quality Improvement Initiatives in Sepsis in an Emerging Country
This quality improvement initiative in sepsis in an emerging country was associated with a reduction in mortality and with improved compliance with quality indicators. However, this reduction was sustained only in private... read more
Utility and Diagnostic Accuracy of Bedside Lung Ultrasonography During MET
Lung ultrasonography can be rapidly performed in the majority of patients with MET activation for respiratory deterioration. As an independent diagnostic test, lung ultrasonography is non-inferior to the medical emergency... read more
Preventing Harm in the ICU – Building a Culture of Safety and Engaging Patients and Families
Preventing harm remains a persistent challenge in the ICU despite evidence-based practices known to reduce the prevalence of adverse events. This review seeks to describe the critical role of safety culture and patient and... read more
Technologic Distractions
Summary of Approaches to Manage Alert Quantity With Intent to Reduce Alert Fatigue and Suggestions for Alert Fatigue Metrics. Approaches for managing alert fatigue in the ICU are provided as a result of reviewing tested interventions... read more
Clinicians’ Perception and Experience of Organ Donation From Brain-Dead Patients
ICU clinicians are primarily involved in organ donation after brain death of ICU patients. Their perceptions of organ donation may affect outcomes. Our objective was to describe ICU clinician’s perceptions and experience... read more
Unplugged & Reconnected – Recovering from Burnout
Does your desk ever look like this? Mine does. WAY too often. Insert the piles of papers, books, journals and mail I need to get to on the side also. When I look at this photo, it seems absolutely ridiculous. Why on earth... read more
Noninvasive Ventilation in Patients With Hematologic Malignancy
Two-thirds of patients with Hematologic Malignancy and respiratory failure failed Noninvasive Ventilation (NIV) and required endotracheal intubation, and had high subsequent mortality. Patients who failed NIV had higher Paco2,... read more
Airway Management of The Morbidly Obese Patient
Obesity is a major health care dilemma. All aspects of medical care, including anesthesia, are affected by it. All physiologic systems are altered by obesity, which imparts a higher risk for complications in the perioperative... read more
5-Year Trends of Critical Care Practice and Outcomes
According to researchers in the U.S., analyses of patients, practices, and outcomes from a large geographically dispersed sample of adult ICUs revealed trends of increasing age and acuity, higher rates of adherence to best... read more
Moral Distress in PICU and Neonatal ICU Practitioners
In this single-center, cross-sectional study, we found that moral distress is present in PICU and neonatal ICU health practitioners and is correlated with burnout, uncertainty, and feeling unsupported. The main outcome was... read more
Early Troponin I in Critical Illness and its Association with Hospital Mortality
TnI is an independent predictor of hospital mortality and correlates most highly with the APS component of APACHE II. It does not improve risk prediction. We would not advocate the adoption of routine troponin analysis on... read more