Oxygen Support Needs in Children with RSV vs. COVID-19
Children with respiratory syncytial virus (RSV) had a higher risk of pneumonia, bronchiolitis, and a hospital stay of more than 4 days vs children with COVID-19 or influenza. Investigators compared demographic and clinical... read more
Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients
Unmodified risk variables for nosocomial bloodstream infections (BSIs) included male sex and leukocytosis at admission. Using methylprednisolone and obtaining a cumulative dosage of dexamethasone were adjusted risk variables... read more
Bronchoscopy in ICU: A Practical Guide
This practical guide focuses on Bronchoscopy in ICU. Bronchoscopy is one of the most commonly performed medical procedures, but is limited to the practice of a handful chest physicians and surgeons. The field of bronchoscopy... read more
Correlation of Common Carotid Artery Blood Flow Parameters With TTE-CO for Assessing Fluid Responsiveness After PLR Test in Critically Ill Patients
The passive leg raising (PLR) test is a simple, non-invasive method of knowing fluid responsiveness by acting as an internal-fluid challenge. The PLR test coupled with a non-invasive assessment of stroke volume would be the... read more
The Song of the Cell: An Exploration of Medicine and the New Human
In the late 1600s, Mukherjee sets the stage for an extraordinary tale. It revolves around two notable individuals: Robert Hooke, a renowned English polymath, and Antonie van Leeuwenhoek, an eccentric Dutch cloth-merchant.... read more
Choosing Wisely Interventions to Reduce Antibiotic Overuse
These real-world multicomponent interventions responding to physician pay-for-performance (P4P) incentives were associated with substantial reductions in antibiotic prescriptions for acute respiratory tract infections (ARTIs)... read more
Why We Can Thank a Polio Emergency for the Birth of Intensive Care
An outbreak of polio in 1950s Denmark led one hospital to pioneer mechanical ventilation, constant monitoring of vital signs and other innovations that are saving lives to this day. The COVID-19 pandemic has brought home... read more
The Autumn Ghost: How the Battle Against a Polio Epidemic Revolutionized Modern Medical Care
"The Autumn Ghost" is a suspenseful and authoritative account that explores how the battle against a polio epidemic in the mid-20th century led to a revolution in medical care. Dr. Hannah Wunsch focuses on the autumn... read more
Comparison of ETA and BALF mNGS in Severe Pneumonia
Our study showed that some differences in the microbiological diagnosis via endotracheal aspirate (ETA) mNGS and bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) appear to exist. Clinicians... read more
Increased Fungal Infections Hospitalizations during COVID-19
An examination of a large healthcare database in the United States revealed a significant rise in hospitalization rates related to fungal infections between 2019 and 2021. This increase was primarily driven by hospitalizations... read more
Verticalization Therapy for ARDS Patients Receiving VV-ECMO
Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more
Heparin-Binding Protein Predictive Value and D-Dimer in Sepsis Patients
As common clinical indicators for predicting sepsis, both HBP and D-dimer have high diagnostic effectiveness. Furthermore, the combined application of these two biomarkers can achieve favorable effects. In clinical practice,... read more
Fluid Responsiveness Evaluation with Integrated Ultrasonographic Approach
In a group of non-ventilated patients, who had already undergone the initial resuscitation, we demonstrated that the evaluation of the fluid responsiveness (FR) based on echocardiography and lung ultrasound increased the... read more
Prostacyclin Anticoagulation Efficacy in Critically Ill Patients Requiring Extracorporeal Support
Extracorporeal support modalities are highly prothrombotic. Anticoagulation is frequently used for patients receiving Continuous Renal Replacement Therapy (CRRT), Molecular Adsorbent Recirculating System (MARS), and Extracorporeal... read more
Albumin Infusion May Decrease the Mortality of Hypoalbuminemia Patients with Severe Acute Pancreatitis
Our study revealed that the lowest albumin level within 1 week after admission was independently associated with mortality in severe acute pancreatitis (SAP). In addition, infusing albumin may decrease mortality for hypoalbuminemia... read more
Plasmodium Vivax Presenting with Septic Shock and Disseminated Intravascular Coagulation
Malaria has various causative agents that can have a spectrum of disease manifestations, some potentially fatal. Various species have been established as etiologies of malaria, though our understanding of the severity of... read more
Disseminated Intravascular Coagulation in COVID-19 Setting
Disseminated intravascular coagulation (DIC) is an acquired syndrome that can lead to catastrophic thrombosis and hemorrhage. In DIC, an uncontrolled release of pro-inflammatory mediators activates tissue factor-dependent... read more
CEUS Value in Diagnosis of AKI in ICU patients
Ultrasound can assess renal perfusion, but its role in the evaluation of acute kidney injury (AKI) is still unclear. This prospective cohort study was to investigate the value of contrast-enhanced ultrasound (CEUS) in the... read more
Ciprofol Sedation Efficacy and Safety in Mechanical Ventilated ICU Patients
Ciprofol was well tolerated, with a noninferior sedation profile to propofol in Chinese ICU patients undergoing MV for a period of 6–24 hours. Of the 135 patients enrolled, 129 completed the study. The primary endpoint-sedation... read more
Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care
This book establishes the indications for the use of NIV in the context of weaning from invasive mechanical ventilation. It provides a comprehensive overview of key topics relevant for correct practical application, including... read more
Effective Treatment for Combined Amlodipine and Metformin Overdose
The combined toxicity of amlodipine and metformin is a rarely reported phenomenon in the literature. The management varies depending on the clinical status of the patient. We present a case that was managed successfully... read more
Dexmedetomidine Improved Sleep Quality in the ICU After Laryngectomy
This pilot study found that a 0.03 μg/kg/h dexmedetomidine infusion improved objective and subjective sleep quality in patients admitted to the ICU after laryngectomy. The dosing regimen used was safe and feasible for use... read more
