Handbook of Drugs in Intensive Care: An A-Z Guide
Now in its sixth edition, the Handbook of Drugs in Intensive Care is the essential guide to using drugs safely and effectively in the intensive care setting. The book is split into two sections: an A-Z guide to the drugs... read more
Scarred Lungs: Identifying Fibrosis Risk After COVID-19 ARDS
This substudy of the large, multicenter RECOVIDS cohort investigated the predictive factors for developing fibrotic changes (FC) in survivors of COVID-19-related Acute Respiratory Distress Syndrome (ARDS) six months after... read more
DeLLiriuM: LLMs Predict Delirium Risk in the ICU
DeLLiriuM is a novel large language model (LLM) designed to predict delirium in Intensive Care Unit (ICU) patients after the initial 24 hours of admission, using structured electronic health records (EHR). What sets DeLLiriuM... read more
Conquer Your Toughest Gift-Giving Challenge (and Save Big!)
Ready to sleigh your holiday shopping list before the stress sets in? From the avid baker and the dedicated gamer to the crafty artist, you'll find the perfect, thoughtful gift for every interest at Amazon's holiday store. You... read more
Gut Feeling vs. Data: SDD Doesn’t Beat Standard Care for Ventilated Patients
This multi-center trial, spanning 26 Intensive Care Units (ICUs) in Australia and Canada and involving over 20,000 critically ill patients on mechanical ventilation, put a long-debated practice, Selective Decontamination... read more
The Crystal Ball of the ICU: Machine Learning Predicts Who’s Staying and Who’s Not
The PREMIER Study dove into the data of 996 patients experiencing Acute Hypoxemic Respiratory Failure (AHRF) who had been on mechanical ventilation (MV) for at least two days, aiming to develop a reliable way to predict their... read more
Defending the Vulnerable: Neutropenic Sepsis Outcomes Improve Despite Higher Risk
A decade-long, single-center study in a French ICU examined the characteristics and outcomes of 185 consecutive patients admitted with neutropenic sepsis or septic shock between 2012 and 2022. The analysis revealed a... read more
SOFA-2: Close, But Not Quite the Ideal Measure of Organ Failure
The SOFA-2 (Sequential Organ Failure Assessment) score represents the latest effort to provide a simple, reliable, and continuous measure of organ dysfunction in critically ill patients, a concept first outlined decades ago.... read more
Beyond Liver Failure: MELD-XI Predicts Sepsis Mortality
This retrospective cohort study investigated the utility of the MELD-XI (Model for End-Stage Liver Disease-Excluding INR) score as a predictor of 30-day mortality in over 16,600 adult ICU patients with sepsis, using data... read more
The Vitamin C Verdict: Not a COVID-19 Mortality Fix
This systematic review and meta-analysis investigated the efficacy of Vitamin C as a treatment for COVID-19, focusing on key patient outcomes like mortality and critical care resource utilization. Objective: To determine... read more
Mechanical Ventilation in Emergency Medicine
This book discusses mechanical ventilation in emergency settings, covering the management of patients from the time of intubation until transfer to the ICU. It provides an introduction to key concepts of physiology pertinent... read more
The Sepsis Chain of Survival: Breaking the Cycle
This framework offers a systematic and adaptable approach to improving outcomes for patients with suspected sepsis. Borrowing from the successful Cardiac Arrest Chain of Survival, the Sepsis Chain emphasizes a seamless series... read more
Kidney Caution: The Polyuria Peril of Prolonged Sevoflurane in the ICU
This observational study investigated the renal impact of prolonged sevoflurane sedation in Intensive Care Unit (ICU) patients, focusing specifically on the incidence of polyuria (excessive urine output, defined as > 3000... read more
Clinical Examination Skills in the Adult Critically Ill Patient
This well-illustrated book provides detailed guidance on all aspects of physical examination in patients requiring emergency or intensive care. After an introductory section covering basic principles and the recognition of... read more
Intensivists Take the Tracheostomy Lead: The Bedside Imperative
The broader adoption of intensivist-led, bedside percutaneous dilatational tracheostomy (PDT) is the new standard of care in modern critical care. The evolution of PDT reflects the increasing procedural autonomy of intensivists... read more
Management of Dysregulated Immune Response in the Critically Ill
This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic... read more
Corticosteroids in ARDS: Delaying High-Dose Methylprednisolone Doesn’t Kill
This large retrospective study investigated whether starting high-dose (2 mg/kg) methylprednisolone therapy after 14 days of Acute Respiratory Distress Syndrome (ARDS) onset increased the risk of complications or mortality... read more
Dexmedetomidine’s ICU Advantage: Faster Exit, Longer Stay?
This updated meta-analysis compared the outcomes of using dexmedetomidine versus other standard sedatives in mechanically ventilated patients with sepsis. Objective: To synthesize recent evidence (2020–2025) from Randomized... read more
Voice Breakthrough: Bringing Speech Back to Ventilator Patients
This retrospective cohort study investigated the safety and success of placing a speaking valve in-line with the mechanical ventilator circuit for critically ill, tracheostomized patients who struggled to wean from the ventilator. Study... read more
Mechanical Ventilation in the ICU: A New Approach and Treatment
In the present book, a broad description of the processes carried out in patients with mechanical ventilation in the ICU is made. It covers from an overview of mechanical ventilation and some of its history to the processes... read more
NAC Dosing Dilemma: Balancing Better Outcomes with Higher Costs in Pneumonia
This study performed a cost-effectiveness analysis comparing the use of two versus three dosage forms of N-acetylcysteine (NAC) as an adjunctive mucolytic therapy for ICU patients with pneumonia. Study Summary and Key... read more
Opioid Use in Critical Care: A Practical Guide
This book provides a concise yet comprehensive overview on the use of opioids in the ICU, offering practical, real-world recommendations on opioid utilization and alternative therapies. The text explains the physiology... read more
