Selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors in pregnancy
This position statement provides guidance for the monitoring, care, and follow-up of newborns exposed to selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) in utero. Depression... read more
Intensive care–treated cardiac arrest: a retrospective study on the impact of extended age on mortality, neurological outcome, received treatments and healthcare-associated costs
The elderly ICU-treated CA patients in this study had worse neurological outcomes, higher mortality and lower cost-effectiveness than younger patients. Elderly received less intense treatment. Further efforts are needed... read more
COVID-19: a boost for intensive care authorship?
Almost 180 million cases of COVID-19 have been diagnosed, with almost 4.000.000 deaths. Since this pandemic had unprecedented worldwide healthcare and socio-economic effects, the scientific world is under exceptional pressure... read more
Sedation Practices and Characteristics of Ventilated Patients
Patients on mechanical ventilator experience anxiety and physiological stress. Sedating them can help those patients to cope up with ET tube, to bear all the interventions, for accessing adequate oxygenation and above... read more
Inhaled Sedation in the ICU: A New Option and Its Technical Prerequisites
Andreas Meiser summarizes the current literature on inhalation sedation of critically ill patients. To meet clinical demands, he describes the development of new devices to administer volatile anesthetics together with common... read more
Diaphragm Ultrasonography in ICU: Why, How, and When To Use It?
An overview of the principles and current applications of diaphragm ultrasound and innovative ultrasound-based techniques. In the ICU, ultrasound is starting to be acknowledged as a useful tool for studying the diaphragm.... read more
Severe Neonatal Hypernatremia
Neonatal hypernatraemia at this level, in this population, is strongly associated with weight loss. It occurs almost exclusively after attempts to initiate breast feeding, occurs uncommonly and does not appear to be associated... read more
Multi-task Prediction of Organ Dysfunction in ICUs
The intensive care unit (ICU) of a hospital looks after the most medically vulnerable patients, many of whom require organ support, such as mechanical ventilation or dialysis. While always critical, the demand on ICU services... read more
Managing Rising COVID-19 Cases in ICU
I have been working in intensive care for over 20 years, including a decade as a consultant, and facing winter pressures has always been the norm. However, the past 18 months have been something else. During the winter... read more
Incidence of Arrhythmia Higher in COVID-19 vs. Other CAPs
The incidence of arrhythmia was higher in COVID-19 than in other community-acquired pneumonia (CAP), with 2 out of 10 COVID-19 patients dying after developing arrhythmia. Higher incidence rates of conduction disorders... read more
COVID-19 Restructures the Host Chromatin Architecture
SARS-CoV-2 has made >190-million infections worldwide, thus it is pivotal to understand the viral impacts on host cells. Many viruses can significantly alter host chromatin, but such roles of SARS-CoV-2 are largely unknown.... read more
Effects of Early Mobilization on the Prognosis of Critically Ill Patients
Early mobilization was effective in enhancing the recovery of critically ill patients, but more large-scale, multicenter randomized controlled trials are required to further confirm these findings. A total of 39 articles... read more
Point of Care Ultrasound
Compact, hand-carried ultrasound devices are revolutionizing how healthcare providers practice medicine in nearly every specialty. The 2nd Edition of this award-winning text features all-new chapters, a greatly expanded... read more
POCUS Diagnosis of Medial Plantar Artery Pseudoaneurysm Secondary to Penetrating Injury
Pseudoaneurysms of the foot are rare and can occur from a range of etiologies, including laceration from a foreign body. The majority of reported cases have been diagnosed by computed tomography, magnetic resonance imaging,... read more
Personalized Mechanical Ventilation in ARDS
A personalized mechanical ventilation approach for patients with adult respiratory distress syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging, and biological phenotypes may improve ventilation... read more
When Could Airway Plateau Pressure is Acceptable in ARDS Patients?
Limitation of plateau pressure (Pplateau) is critical for pro-tection from ventilator-induced lung injury in patients with acute respiratory distress syndrome (ARDS). Limiting to a 30 cmH2O threshold is a widely accepted... read more
Neuropsychiatric Disorders and COVID-19
We read with interest the Article by Maxime Taquet and colleagues1 in The Lancet Psychiatry that evaluated a large population (n=236 379) for neurological and psychiatric complications of COVID-19 via analysis of diagnostic... read more
The Gut in COVID‑19
In the last year, a growing number of articles addressed coronavirus disease 2019 (COVID-19), including its link with gastrointestinal (GI) (dys)function. We here highlight the most important findings regarding the role of... read more
Transcatheter arterial embolization for severe blunt liver injury in hemodynamically unstable patients
Transcatheter arterial embolization (TAE) in hemodynamically unstable patients who responded to initial infusion therapy to some extent has acceptable in-hospital mortality and clinical failure rates. Hemodynamic instability... read more
Effect of Graded Early Mobilization on Psychomotor Status and Length of ICU Stay in Mechanically Ventilated Patients
This research showed that graded early mobilization was highly effective to improve the motor and psychological status of mechanically ventilated patients and reduce their length of ICU stay. In the control group mean... read more
Prone Positioning and Survival in Mechanically Ventilated Patients with COVID-19
In-hospital mortality was lower in mechanically ventilated hypoxemic patients with coronavirus disease 2019 treated with early proning compared with patients whose treatment did not include early proning. Among 2,338 eligible... read more
Liver Dysfunction and COVID-19 Infection
Severe acute respiratory syndrome coronavirus 2 infection is the cause of coronavirus disease 2019 (COVID-19), which predominantly affects the respiratory system; it also causes systemic and multi-organic disease. Liver... read more
