Dexmedetomidine for Prolonged Sedation in the PICU

Dexmedetomidine for Prolonged Sedation in the PICU

High-quality data on dexmedetomidine use for prolonged sedation and a consensus on correct dosing and weaning protocols in children are currently missing. Infusion of dexmedetomidine can be considered relatively safe in pediatrics... read more

The Impact on Pediatric Emergency Care during COVID-19

The Impact on Pediatric Emergency Care during COVID-19

Although most children with COVID-19 are asymptomatic or present with mild disease, serious—but rare—complications are being seen in pediatric patients. This supplement describes the epidemiology, clinical features, and... read more

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

In this case series of hospitalized children who met criteria for PIMS-TS, there was a wide spectrum of presenting signs and symptoms and disease severity, ranging from fever and inflammation to myocardial injury, shock,... read more

Pediatric Airway Management in COVID-19 Patients

Pediatric Airway Management in COVID-19 Patients

The severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic has challenged medical systems and clinicians globally to unforeseen levels. COVID-19's rapid spread has forced clinicians to care for patients with... read more

New Technology Gives Parents Virtual Face Time With Their Hospitalized Children

New Technology Gives Parents Virtual Face Time With Their Hospitalized Children

The pediatric intensive care unit (PICU) team at the University of Maryland Children's Hospital (UMCH) is offering a new way for families to interact with their child and the medical team when they can’t be there in person. PICU... read more

Echocardiography in Pediatric and Congenital Heart Disease

Echocardiography in Pediatric and Congenital Heart Disease

This comprehensive textbook on the echocardiographic assessment of pediatric and congenital heart disease has been updated for a second edition with an emphasis on new technologies. This highly-illustrated full-color reference... read more

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

A large cohort of international experts was able to achieve consensus regarding many recommendations for the best care of children with sepsis, acknowledging that most aspects of care had relatively low quality of evidence... read more

Blood Transfusion – Fresh vs. Standard-issue in Critically Ill Pediatric Patients

Blood Transfusion – Fresh vs. Standard-issue in Critically Ill Pediatric Patients

Among critically ill pediatric patients, the use of fresh red blood cells did not reduce the incidence of new or progressive multiple organ dysfunction syndrome (including mortality) compared with standard-issue red blood... read more

Neonatal Lung Ultrasonography

Neonatal Lung Ultrasonography

This book presents lung ultrasound as an accurate, reliable, low-cost and simple imaging technique, which poses no risk of radiation damage, making bedside use both feasible and convenient in neonatal wards. The aim of... read more

Depth of Anesthesia in Children Undergoing Cardiac Surgery Under Extracorporeal Circulation

Depth of Anesthesia in Children Undergoing Cardiac Surgery Under Extracorporeal Circulation

In children undergoing cardiac surgery in our department, the use of sevoflurane-balanced anesthesia during cardiopulmonary bypass showed no superiority of inhalational agents over total intravenous anesthesia with opioids... read more

Holding Intubated Infants Well Tolerated and Safe

Holding Intubated Infants Well Tolerated and Safe

Critically ill infants who are old enough to move on their own but too young to cooperate with care instructions have been among the last to benefit from patient mobility initiatives. Results from a holding intervention... read more

Serum Protein Changes in Pediatric Sepsis Patients Identified with an Aptamer-Based Multiplexed Proteomic Approach

Serum Protein Changes in Pediatric Sepsis Patients Identified with an Aptamer-Based Multiplexed Proteomic Approach

The serum protein changes identified with the aptamer-based multiplexed proteomics approach used in this study can be useful to distinguish between sepsis and noninfectious systemic inflammation. A cohort of 40 children... read more

Optimal Duration of Mechanical Ventilation and Influencing Factors Following Mandibular Distraction Osteogenesis in Infants

Optimal Duration of Mechanical Ventilation and Influencing Factors Following Mandibular Distraction Osteogenesis in Infants

Mandibular distraction osteogenesis (MDO) is an effective treatment for tongue-based airway obstruction in infants with severe Pierre Robin sequence (PRS). Most infants receiving MDO require postoperative mechanical ventilation... read more

Changes in Anesthetic and Postoperative Sedation-Analgesia Practice Associated With Early Extubation Following Infant Cardiac Surgery

Changes in Anesthetic and Postoperative Sedation-Analgesia Practice Associated With Early Extubation Following Infant Cardiac Surgery

The implementation of an early extubation clinical practice guideline resulted in a reduction in the dose of opioids and benzodiazepines without a change in volatile anesthetic agent used in the operating room. Intraoperative... read more