Bridging the Gap Between Intensivists and Primary Care Clinicians in ECMO for Respiratory Failure in Children

All pediatric clinicians should be aware not only of the potential benefits and complications of ECMO but also that survivors need effective screening, support, and follow-up. The 2009 influenza A(H1N1) pandemic, along... read more

Bridging the Gap Between Intensivists and Primary Care Clinicians in ECMO for Respiratory Failure in Children

High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure

The use of high-flow nasal oxygen upon ICU admission in adult patients with COVID-19 related acute hypoxemic respiratory failure may lead to an increase in ventilator-free days and a reduction in ICU length of stay, when... read more

High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure

Respiratory Support in Patients with COVID-19

Non-invasive respiratory support could be useful in treating COVID-19-related acute respiratory failure (ARF). A rational use of different techniques (oxygen therapy, CPAP, NIV or HFOT) by a trained pulmonologist could allow... read more

Respiratory Support in Patients with COVID-19

Automated vs. Conventional Ventilation in the ICU

Automated ventilation (AV) appears to reduce the incidence and severity of blood oxygen desaturation during daily nursing procedures (DNPs) in comparison to Conventional Ventilation (CV). Of the 265 included patients,... read more

Automated vs. Conventional Ventilation in the ICU

Respiratory Strategies for Patients with Suspected or Proven COVID-19 Respiratory Failure

The trial objective is to determine if Continuous Positive Airway Pressure (CPAP) or High-Flow Nasal Oxygen (HFNO) is clinically effective compared to standard oxygen therapy in patients with confirmed or suspected COVID-19. The... read more

Respiratory Strategies for Patients with Suspected or Proven COVID-19 Respiratory Failure

Development of Persistent Respiratory Morbidity in Previously Healthy Children After ARF

Persistent respiratory morbidity develops in up to potentially 44% of previously healthy children less than or equal to 24 months old at follow-up after acute respiratory failure (ARF) requiring mechanical ventilation. This... read more

Development of Persistent Respiratory Morbidity in Previously Healthy Children After ARF

Long-Term Health-Related Quality of Life After Venovenous Extracorporeal Membrane Oxygenation

This study examined the long-term health-related quality of life in adult patients treated with venovenous extracorporeal membrane oxygenation (V-V ECMO) for severe acute respiratory failure in Ireland. A retrospective, cross-sectional... read more

Long-Term Health-Related Quality of Life After Venovenous Extracorporeal Membrane Oxygenation

Prone Positioning in Nonintubated Patients with COVID-19 and Hypoxemic Acute Respiratory Failure

In this study of patients with COVID-19 and hypoxemic respiratory failure managed outside the ICU, 63% were able to tolerate PP for more than 3 hours. However, oxygenation increased during PP in only 25% and was not sustained... read more

Prone Positioning in Nonintubated Patients with COVID-19 and Hypoxemic Acute Respiratory Failure

Acute Respiratory Failure in COVID-19: Typical ARDS?

COVID-19 is highly infectious and can lead to fatal comorbidities especially ARDS. There are currently no recommended specific anti-COVID-19 treatments, so supportive treatment is important. Fully understanding the characteristics... read more

Acute Respiratory Failure in COVID-19: Typical ARDS?

COVID-19 Patients with Respiratory Failure: What Can We Learn From Aviation Medicine?

Patients with COVID-19 may present to hospitals and emergency medical services with an atypical form of acute respiratory distress syndrome (ARDS). Although anecdotal, a common clinical pattern has emerged, with a remarkable... read more

COVID-19 Patients with Respiratory Failure: What Can We Learn From Aviation Medicine?

Severe Influenza in Critically Ill Patients

The present review summarizes current knowledge on pathogenesis and clinical manifestations of severe influenza. Immunological dysfunction during viral infection correlates with severity and mortality among ICU patients.... read more

Severe Influenza in Critically Ill Patients

High-Flow Nasal Cannula vs. Noninvasive Ventilation

High-flow conditioned oxygen therapy delivered through nasal cannulae and noninvasive mechanical ventilation (NIV) may reduce the need for reintubation. Therefore, Hernández et al set out to test if high-flow conditioned... read more

High-Flow Nasal Cannula vs. Noninvasive Ventilation

Effect of Vitamin C Infusion on Organ Failure in Patients With Sepsis and ARDS

In this preliminary study of patients with sepsis and Acute Respiratory Distress Syndrome (ARDS), a 96-hour infusion of vitamin C compared with placebo did not significantly improve organ dysfunction scores or alter markers... read more

Effect of Vitamin C Infusion on Organ Failure in Patients With Sepsis and ARDS

Early Mobilization Reduces Duration of Mechanical Ventilation and Intensive Care Unit Stay in Patients With ARF

The introduction of early mobilization for patients with mechanical ventilation (MV) in the ICU shortened MV durations and ICU stays. A multidisciplinary team that includes the patient's family can work together to improve... read more

Early Mobilization Reduces Duration of Mechanical Ventilation and Intensive Care Unit Stay in Patients With ARF

Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care

Randomized clinical trials (RCTs) are conducted to guide clinicians' selection of therapies for individual patients. Currently, RCTs in critical care often report an overall mean effect and selected individual subgroups.... read more

Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care