1-year Mortality After COVID-19 ICU Admission

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes severe disease in some patients. Patients can experience severe disabilities after intensive care unit (ICU) admission due to coronavirus disease... read more

1-year Mortality After COVID-19 ICU Admission

Post-acute Neurological Consequences of COVID-19

COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity. Our world has witnessed over 275 million confirmed cases of COVID-19... read more

Post-acute Neurological Consequences of COVID-19

Immunological Dysfunction Persists for 8 months Following Initial Mild-to-Moderate COVID-19 Infection

A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here, we studied individuals with LC compared to... read more

Immunological Dysfunction Persists for 8 months Following Initial Mild-to-Moderate COVID-19 Infection

Effect of Early Fluvoxamine Treatment Among COVID-19 Patients

Treatment with fluvoxamine (100 mg twice daily for 10 days) among high-risk outpatients with early diagnosed COVID-19 reduced the need for hospitalisation defined as retention in a COVID-19 emergency setting or transfer to... read more

Effect of Early Fluvoxamine Treatment Among COVID-19 Patients

Early Remdesivir to Prevent Progression to Severe COVID-19 in Outpatients

Among nonhospitalized patients who were at high risk for Covid-19 progression, a 3-day course of remdesivir had an acceptable safety profile and resulted in an 87% lower risk of hospitalization or death than placebo. A... read more

Early Remdesivir to Prevent Progression to Severe COVID-19 in Outpatients

Omicron Magnifies the Distress in the Health Care Labor System

In December 2020, to the tune of rousing cheers, the first health care workers began getting vaccinated against COVID-19. A year later, the cheers have died down, vaccination rates have plateaued, and the Omicron wave... read more

Omicron Magnifies the Distress in the Health Care Labor System

COVID-19 Guidance for Hospital Reporting and FAQs

Hospitals are responsible for reporting the information to the Federal government. Facilities should report at the individual hospital level, even if hospitals share a Centers for Medicare & Medicaid Services (CMS) Certification... read more

COVID-19 Guidance for Hospital Reporting and FAQs

Risk Factors for Severe COVID-19 Outcomes Among Adults Who Completed a Primary COVID-19 Vaccination

In this analysis of data from 465 U.S. health care facilities, severe COVID-19 outcomes (i.e., respiratory failure, ICU admission, or death) were rare among adults aged ≥18 years after primary vaccination. These findings... read more

Risk Factors for Severe COVID-19 Outcomes Among Adults Who Completed a Primary COVID-19 Vaccination

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

The research will be retrospective, and will include a review of medical history of all patients admitted in the COVID-19 ICU of the University hospital Osijek during 2020 and 2021. Associated comorbidity, hospital admission... read more

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

Anticoagulation in COVID-19

Thrombotic complications (arterial and venous) are common in patients admitted to hospital with COVID-19 and are an independent predictor of poor outcome. Microvascular thrombi also contribute to organ dysfunction, including... read more

Anticoagulation in COVID-19

EPs Who Spread Misinformation Could Face Loss of Board Certification

Parallel pandemics have bedeviled the United States since the first cases of COVID-19 were recognized. As cases and deaths surged, so did the misinformation, and those false statements gained credibility when they came from... read more

EPs Who Spread Misinformation Could Face Loss of Board Certification

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths worldwide and countless more admissions to hospitals and ICUs. Since... read more

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Biomarker-guided Steroid Dosing in COVID-19 Pneumonia

Although corticosteroid administration has been associated with improved outcomes in severe COVID-19 pneumonia, their ideal use remains undefined with a "one size fits all" approach used, irrespective of the individual inflammatory... read more

Biomarker-guided Steroid Dosing in COVID-19 Pneumonia

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

An overall good trial that supports the use of high flow oxygen therapy in patients with Severe COVID-19. Randomized controlled trial conducted across three centers in Columbia over 5 months from August 2020 to January... read more

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

Mesenchymal Stem/Stromal Cell-based Therapies for Severe Viral Pneumonia

Severe viral pneumonia is a significant cause of morbidity and mortality globally, whether due to outbreaks of endemic viruses, periodic viral epidemics, or the rarer but devastating global viral pandemics. While limited... read more

Mesenchymal Stem/Stromal Cell-based Therapies for Severe Viral Pneumonia

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

During the COVID-19 pandemic, despite early concerns the impact oral corticosteroids might have on the effects of acute COVID-19 reported by the WHO and the potential severity of disease in patients with asthma and chronic... read more

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

Healthcare Worker Safety and COVID-19

It had been apparent from the start of the pandemic that both patients and healthcare workers are at significant risk of acquiring COVID-19 in hospitals. In an early report from Wuhan more than 40% of infections were hospital-acquired,... read more

Healthcare Worker Safety and COVID-19

VTE Diagnosis and Treatment in the COVID-19 Era

This is a very interesting time to be an intensivist with a research interest in blood clots. As such I wanted to use this time to talk about how COVID 19 has changed our approach to diagnostics, therapeutics and even to... read more

VTE Diagnosis and Treatment in the COVID-19 Era

Atlas of Chest Imaging in COVID-19 Patients

This book presents X-ray and CT findings of patients with 2019 Novel Coronavirus (2019-nCoV) pneumonia in early, progressive, critical, and recover stage. It starts with a general review of CT features of new coronavirus... read more

Atlas of Chest Imaging in COVID-19 Patients

Inhaled Amphotericin B Lipid Complex for Prophylaxis Against COVID-19-associated Invasive Pulmonary Aspergillosis

Recently, Prattes and colleagues published in Intensive Care Medicine a high incidence of coronavirus disease 2019-associated invasive pulmonary aspergillosis (CAPA), according to 2020 ECMM/ISHAM consensus criteria, with... read more

Inhaled Amphotericin B Lipid Complex for Prophylaxis Against COVID-19-associated Invasive Pulmonary Aspergillosis

Dynamic Prediction Tool for Mortality in COVID-19 Ventilated Patients

The COVID-19 pandemic has caused intensive care units (ICUs) to reach capacities requiring triage. A tool to predict mortality risk in ventilated patients with COVID-19 could inform decision-making and resource allocation,... read more

Dynamic Prediction Tool for Mortality in COVID-19 Ventilated Patients