A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients with COVID-19

A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients with COVID-19

Approximately, one in 20 patients hospitalized with coronavirus disease 2019 received resuscitation for an in-hospital cardiac arrest. Hospital survival after in-hospital cardiac arrest within the ICU was higher than non-ICU... read more

Therapeutic vs. Prophylactic Anticoagulation for COVID-19 Patients with Elevated D-dimer Concentration

Therapeutic vs. Prophylactic Anticoagulation for COVID-19 Patients with Elevated D-dimer Concentration

In patients hospitalised with COVID-19 and elevated D-dimer concentration, in-hospital therapeutic anticoagulation with rivaroxaban or enoxaparin followed by rivaroxaban to day 30 did not improve clinical outcomes and increased... read more

Health Systems Successfully Leverage Tele-ICU During Pandemic and Intend to Continue

Health Systems Successfully Leverage Tele-ICU During Pandemic and Intend to Continue

Help during the pandemic for overwhelmed, overworked intensive care unit (ICU) nurses at some health systems came in the form of experienced tele-ICU nurses working remotely to support on-site colleagues as they cared for... read more

Protecting The Injured RV in COVID-19 ARDS

Protecting The Injured RV in COVID-19 ARDS

The abnormal interaction between the right ventricle (RV) and pulmonary vasculature in various disease states is associated with adverse clinical outcomes. Impaired RV physiology in acute respiratory distress syndrome (ARDS)... read more

Non-invasive Respiratory Support and P-SILI in COVID-19

Non-invasive Respiratory Support and P-SILI in COVID-19

Coronavirus disease 2019 (COVID-19) pneumonia is associated with hypoxemic respiratory failure, ranging from mild to severe. Due to the worldwide shortage of intensive care unit beds, a relatively high number of patients... read more

Tocilizumab Use May Be Associated with a Short-term Mortality Benefit

Tocilizumab Use May Be Associated with a Short-term Mortality Benefit

For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required. Its benefits may also lie in reducing the... read more

Why and How to Open ICU to Family Visits During the Pandemic

Why and How to Open ICU to Family Visits During the Pandemic

Since the lockdown because of the pandemic, family members have been prohibited from visiting their loved ones in hospital. While it is clearly complicated to implement protocols for the admission of family members, we believe... read more

COVID-19 Pathophysiology: Looking Beyond Acute Disease

COVID-19 Pathophysiology: Looking Beyond Acute Disease

Careful descriptions of the clinical features of acute disease in patients infected with the novel coronavirus SARS-CoV-2 had begun to emerge before WHO declared the outbreak of COVID-19 a public health emergency of international... read more

COVID-19 ARDS has higher EVLWi and PVPI values than non-COVID-19 ARDS

COVID-19 ARDS has higher EVLWi and PVPI values than non-COVID-19 ARDS

Compared to acute respiratory distress syndrome (ARDS) patients without COVID-19, patients with COVID-19 had similar lung mechanics, but higher extravascular lung water index (EVLWi) and pulmonary vascular permeability index... read more

The Predictive Role of Combined Cardiac and Lung Ultrasound in COVID-19

The Predictive Role of Combined Cardiac and Lung Ultrasound in COVID-19

In hospitalized patients with coronavirus disease 2019, a very limited echocardiographic examination is sufficient for outcome prediction. The addition of echocardiography in patients with high-risk MEWS decreases the rate... read more

Risk of Clinical Severity by Age and Race/Ethnicity Among Adults Hospitalized for COVID-19

Risk of Clinical Severity by Age and Race/Ethnicity Among Adults Hospitalized for COVID-19

Older adults and people from certain racial and ethnic groups are disproportionately represented in coronavirus disease 2019 (COVID-19) hospitalizations and deaths. Using data from the Premier Healthcare Database on 181,813... read more

COVID-19 Antibody Seropositivity Longevity Analysis

COVID-19 Antibody Seropositivity Longevity Analysis

Seropositivity of IgG antibodies to both SARS-CoV-2 S and N-proteins followed a linear trend reaching approximately 90% positivity at 21 days post-index. The rate of N-protein seropositivity declined at a sharper rate,... read more

COVID-19 Infection Induces Long-lived Bone Marrow Plasma Cells

COVID-19 Infection Induces Long-lived Bone Marrow Plasma Cells

Population scale sweeps of viral pathogens, such as SARS-CoV-2, require high intensity testing for effective management. Here, we describe "Systematic Parallel Analysis of RNA coupled to Sequencing for Covid-19 screening"... read more

d-dimer and Death in COVID-19 Patients

d-dimer and Death in COVID-19 Patients

In this multicenter cohort study of critically ill adults with COVID-19 admitted to ICUs across the United States, higher d-dimer was independently associated with a greater risk of death. The added value of d-dimer in... read more