Tag: delirium
Multifaceted Early Mobility Intervention Impact for Critically Ill Children
This study will examine whether a multifaceted strategy to optimize early mobility affects the duration of mechanical ventilation, delirium incidence, and functional outcomes in critically ill children. This study will... read more
Delirium Prevention in the ICU: Melatonin or Ramelteon
Melatonin modulates the circadian rhythm and has been studied as a preventive measure against the development of delirium in hospitalized patients. Such an effect may be more evident in patients admitted to the ICU, but findings... read more
Dexmedetomidine vs. Propofol Sedation in Critically Ill Adults Requiring Mechanical Ventilation
Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and the risk of delirium in cardiac surgical patients. It also significantly... read more
Feelings of Strangeness in ICU Patients
After several weeks in the intensive care unit (ICU) following a lung infection, Mr Pol wakes up from a coma and gradually becomes aware of his situation. The healthcare team rejoice in the successful outcome of his extubation:... read more
Difficulties Faced by Nurses Who Care For Patients with Delirium in the ICU
We developed a difficulty scale for nurses caring for patients with delirium in the intensive care unit and confirmed its reliability and validity. The difficulty factors were developed with the intention to identify educational... read more
Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients
Plasma Biomarkers of systemic inflammation and endothelial activation are associated with ED delirium duration in older ED patients without dementia. A total of 156 patients were enrolled. IL-6 (POR = 1.59, 95%CI: 1.09–2.32)... read more
The Family in Preventing Delirium in the ICU
Extended visits, development of family-mediated activities, and redirection are non-pharmacological strategies that reduce the incidence of delirium in the ICU and offer multiple benefits to the patient and family/caregiver. The... read more
Melatonin in ICU Delirium: Shining Light on the Hormone of Darkness
Delirium represents a form of acute brain dysfunction predictive of excess death and long-term cognitive impairment in critically ill patients. For many years, we have wondered whether pharmacological doses of melatonin would... read more
Incidence of Delirium in ICU Inpatients After Cognitive Exercise Intervention
In this study, the relevant RCTs on cognitive exercise in ICU inpatients with delirium were screened for systematic evaluation and meta-analysis, aiming to explore the impact of cognitive exercises and routine nursing on... read more
Processed Electroencephalography-guided General Anaesthesia to Reduce Postoperative Delirium
Our primary analysis demonstrated a highly sensitive result with a pooled analysis of trials in which the intervention group adhered to manufacturer's recommended guidelines showing reduced incidence of postoperative delirium... read more
Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC)
Enteral melatonin initiated within 48 h of ICU admission did not reduce the prevalence of delirium compared to placebo. These findings do not support the routine early use of melatonin in the critically ill. A total of... read more
Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score
The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S) is an automated, physiologic measure of delirium severity that predicts clinical outcomes with a level of performance comparable to conventional... read more
Association Between Incident Delirium Treatment with Haloperidol and Mortality in Critically Ill Adults
Treatment of incident delirium and its symptoms with haloperidol may be associated with a dose-dependent improvement in survival. Future randomized trials need to confirm these results. Patients were evaluated tid for... read more
Post-acute Neurological Consequences of COVID-19
COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity. Our world has witnessed over 275 million confirmed cases of COVID-19... read more
Preoperative POCUS to Identify Frailty and Predict Postoperative Outcomes
Similar to computed tomography measurements of psoas muscle area, preoperative ultrasound measurements of quadriceps depth shows promise in discriminating between frail and not-frail patients before surgery. It was also associated... read more
