Propofol-Related Infusion Syndrome in a Child with RSE

Propofol is used for sedation, anxiolysis, anesthesia induction, and as an anticonvulsant. In cases of refractory status epilepticus (RSE), propofol is more efficient than barbiturates. We present a case of a 3-year-old... read more

Propofol-Related Infusion Syndrome in a Child with RSE

Age and Associated Outcomes Among Patients Receiving V-A ECMO

In a multinational study using the ELSO Registry, we found that increasing age was strongly associated with higher risk of hospital mortality and complications among patients receiving V-A ECMO for cardiogenic shock, with... read more

Age and Associated Outcomes Among Patients Receiving V-A ECMO

Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

Despite advances in medical therapies and coronary revascularization, infarct-related cardiogenic shock remains a life-threatening emergency with high death rates. Temporary mechanical circulatory support, including peripheral... read more

Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

Using Deep Neural Networks for Survival Prediction in VA-ECMO

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a complex and high-risk life support modality used in severe cardiorespiratory failure. ECMO survival scores are used clinically for patient prognostication... read more

Using Deep Neural Networks for Survival Prediction in VA-ECMO

Anticoagulation in the ICU: Contact Pathway Inhibition Future

Bleeding and thrombotic complications are the main cause of morbidity and mortality in critically ill patients on the intensive care unit (ICU), receiving short-term percutaneous mechanical circulatory support (pMCS) by extracorporeal... read more

Anticoagulation in the ICU: Contact Pathway Inhibition Future

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

During the COVID-19 pandemic, healthcare delivery was affected in various ways. For example, acute and chronic cardiovascular diseases (CVDs) and events were less frequently observed in hospitals, both because public health... read more

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

Remdesivir, an antiviral medication, may benefit patients who are infected with mild or moderate forms of COVID-19 infection. Several research findings have suggested the safety and efficacy of remdesivir for a five- to 10-day... read more

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

VA-ECMO in High-Risk Pulmonary Embolism

High-risk Pulmonary Embolism (PE) has an ominous prognosis and requires emergent reperfusion therapy, primarily systemic thrombolysis (ST). In deteriorating patients or with contraindications to ST, Veno-Arterial Extracorporeal... read more

VA-ECMO in High-Risk Pulmonary Embolism

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Prostacyclin Anticoagulation Efficacy in Critically Ill Patients Requiring Extracorporeal Support

Extracorporeal support modalities are highly prothrombotic. Anticoagulation is frequently used for patients receiving Continuous Renal Replacement Therapy (CRRT), Molecular Adsorbent Recirculating System (MARS), and Extracorporeal... read more

Prostacyclin Anticoagulation Efficacy in Critically Ill Patients Requiring Extracorporeal Support

Barotrauma Rate Is 25% in ARDS Patients Receiving ECMO

Patients with acute respiratory distress syndrome (ARDS) receiving mechanical ventilation have a high risk of barotrauma, which often has poor prognosis and high mortality. Although ECMO should theoretically protect patients... read more

Barotrauma Rate Is 25% in ARDS Patients Receiving ECMO

The Advanced Ventilator Book

The Advanced Ventilator Book is a companion to the best-selling The Ventilator Book and is written for clinicians who already have a solid foundation in the basics of mechanical ventilation. It goes beyond the ventilator... read more

The Advanced Ventilator Book

Heparin-based vs. Bivalirudin-based Anticoagulation in Pediatric ECMO

Bivalirudin may be a safe, cost-effective alternative to heparin in achieving anticoagulation in pediatric extracorporeal membrane oxygenation (ECMO) patients. Prospective multicenter studies and randomized control trials... read more

Heparin-based vs. Bivalirudin-based Anticoagulation in Pediatric ECMO

ECMO in Adult Patients Receiving HCT

Combined advances in hematopoietic cell transplantation (HCT) and intensive care management have improved the survival of patients with hematological malignancies admitted to the intensive care unit. In cases of refractory... read more

ECMO in Adult Patients Receiving HCT

The High-risk Surgical Patient

It is well known that certain diseases and patient conditions are associated with increased perioperative risk. The aim of this book is to define and identify the clinical factors that warrant a broader and more detailed... read more

The High-risk Surgical Patient

Rising Mortality in COVID-19 Patients Supported With ECMO

We aimed to describe practice patterns and outcomes in patients with extracorporeal membrane oxygenation (ECMO) support throughout the coronavirus 2019 (COVID-19) pandemic, with the hypothesis that mortality would improve... read more

Rising Mortality in COVID-19 Patients Supported With ECMO

A Guide to Mechanical Circulatory Support: A Primer for Ventricular Assist Device (VAD) Clinicians

This unique book details a multidisciplinary approach for providers caring for the Mechanical Circulatory Support (MCS) patient. Authors discuss the history of MCS, patient selection, surgical and post-operative care, mobility... read more

A Guide to Mechanical Circulatory Support: A Primer for Ventricular Assist Device (VAD) Clinicians