Tag: ICU
Flow Control Ventilation in ICU
Flow control ventilation is an innovative technique of mechanical ventilation with a potentially lung protective characteristics. The constant inspiratory and expiratory flow, no ventilation pauses, and inspiration to... read more
Dexmedetomidine for Sedation in Pediatric ICU
Audit shows compliance to the standards were not met. A third of the patients required higher doses of up to 2 micrograms/kg/hour of dexmedetomidine. Studies have supported the safety of higher doses of up to 2 micrograms/kg/hour.2... read more
Imaging the ICU Patient
Work in intensive care is dynamic and often requires swift decision-making to achieve the best patient outcome. This book serves as a practical guide for professionals working in this demanding area of medicine. It reviews... read more
ICU-acquired Weakness: Critical Illness Myopathy and Polyneuropathy
Critical illness myopathy (CIM) and critical illness polyneuropathy (CIP) are significant complications in intensive care unit (ICU) patients, first identified in the late 20th century. These conditions often present... read more
Weaning Failure From Mechanical Ventilation
Ultrasound is a useful tool for identifying weaning failure from cardiovascular, diaphragmatic, respiratory, and airway origin. The strengths of our scoping review lie in its comprehensive approach to synthesizing diverse... read more
Peripheral and Respiratory Muscle Weakness and Functional Impairments in ICU Patients
This study demonstrated that patients discharged from ICU in this resource-constrained setting presented with peripheral and respiratory muscle weakness at unit discharge. Muscle weakness occurred despite a short ICU... read more
Massive Pulmonary Embolism with Clot in Transit Using Fluoroscopic and Transthoracic Echocardiographic-Guided Large-Bore Mechanical Thrombectomy
Massive pulmonary embolism (PE) is a life-threatening condition caused by the obstruction of pulmonary arteries requiring precise and timely intervention to prevent mortality. Clots in transit (CIT), which are thrombi... read more
Extubation in the Operating Room After Elective On-pump CABG Surgery
Although immediate extubation in the operating room following on-pump coronary artery bypass graft (CABG) surgery did not show significant differences in ICU or hospital length of stay (LOS), mortality, or ICU readmission... read more
Cytomegalovirus Infection Adverse Impact on ICU Outcomes in COVID-19 Patients
In critically ill patients with SARS-CoV-2 pneumonia, cytomegalovirus (CMV) infection was frequently observed, and associated with increased ICU and hospital mortality. CMV co-infection correlated with a higher incidence... read more
NIV Effectiveness in Critical Patients with ARF and Do Not Intubate Order
The prevalence of do-not-intubate (DNI) order was frequent in patients with acute respiratory failure (ARF) admitted to the ICU, being related to age, comorbidity, frailty and the underlying disease. non-invasive ventilation... read more
Prophylactic NIV Effects on Weaning
The use of prophylactic non-invasive ventilation (NIV) reduced reintubation rates, ICU and hospital length of stay (LOS), and mortality. These findings support the recommendation for its use in daily practice. Rescue... read more
The Association Between Pain, Analgesia, and Delirium in Critically Ill Adults
We observed an association between pain and incident delirium among critically ill adults. Exposure to morphine or fentanyl (but no other pain medications) was associated with increased risk of delirium occurrence. From... read more
Using AI to Detect and Treat Delirium
The prevention of delirium in ICU represents a major unmet need because of its high prevalence, under-diagnosis, and independent association with adverse outcomes including higher mortality and accelerated cognitive decline.... read more
Adult Critical Care Medicine
This clinical casebook provides a comprehensive yet concise state-of-the-art review of adult critical care medicine. Presented in a case-based format, each case focuses on a scenario commonly encountered with an adult patient... read more
Ventilation Practices in ABI Patients and Association with Outcomes
Current mechanical ventilation practices for patients with acute brain injury (ABI) are poorly defined. This study aimed to describe ventilator settings/parameters used in intensive care units (ICUs) and evaluate their association... read more
Standard vs. Double Dosing of Beta-lactam Antibiotics in Critically Ill Sepsis Patients
The BULLSEYE trial is a randomized controlled study designed to enhance the treatment of critically ill patients with septic shock. The concept of administering higher and double doses of beta-lactams in such patients... read more
PCR and Biomarker Algorithms to Guide Antibiotics in Lower Respiratory Tract Infections
Acute chest syndrome (ACS) in sickle cell disease (SCD) is life-threatening and characterised by a new infiltrate on imaging plus fever or respiratory symptoms.1 Causes of ACS include infections, venous or fat embolisms or... read more
Blood Glucose and Clinical Outcomes After ECC
Postoperative blood glucose levels significantly impact outcomes in cardiac surgery patients undergoing extracorporeal circulation (ECC) auxiliary to open heart surgery. The study's primary outcome was the 90-day mortality,... read more
Tracheostomy in COVID-19 Patients
Tracheostomy is common in critically ill COVID-19 patients. In patients predicted to need a tracheostomy at some point, early, rather than late, tracheostomy might be a means to reduce the time spent in ICU. However,... read more
Pirfenidone to Prevent Fibrosis in ARDS
Pulmonary fibrosis is a major complication of the Acute Respiratory Distress Syndrome (ARDS). Pirfenidone is an approved treatment for idiopathic pulmonary fibrosis. It may attenuate ARDS-related fibrosis and decrease the... read more
Association Between Osteopontin and Apolipoprotein E gene Polymorphisms and Vancomycin-induced AKI
Individuals carrying specific genotypes of APOE (e2e3) were more prone to develop vancomycin-induced acute kidney injury (AKI), per se. This could apply to other nephrotoxic agents as well. We also observed a significant... read more
Severe COVID-19 Early Identification and the Need for ICU Care Based on Objective Risk Factors
The study found that several factors, including advanced age; male gender; and comorbid conditions like diabetes, chronic lung disease, and CVD had a strong association with ICU admission among COVID-19 patients. Similarly,... read more
