Maternal Risk Modeling in Critical Care

Risk prediction models specific to the maternal critical care population was developed. The models compare favorably against general adult ICU risk prediction models in current use within this population. The aim was to... read more

Impact of Levosimendan on Weaning from Peripheral VA-ECMO in ICU

This study suggests that levosimendan might be associated with a beneficial effect on venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in ICU patients. The difference in mortality among propensity-matched... read more

Intravenous Fluid Therapy in Critically Ill Adults

Despite the administration of intravenous fluids to critically ill patients being a near-universal intervention, the available evidence base guiding their safe and appropriate use is scarce and derived mainly from academically... read more

Measuring Patient Mobility in the ICU Using a Novel Noninvasive Sensor

Noninvasive mobility sensor is a novel and feasible method for automating evaluation of ICU patient mobility. Three Microsoft Kinect sensors (Microsoft, Beijing, China) were deployed in one ICU room to collect continuous... read more

Effect of Stress Ulcer Prophylaxis on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation

Among ICU patients requiring mechanical ventilation, a strategy of stress ulcer prophylaxis with use of proton pump inhibitors vs histamine-2 receptor blockers resulted in hospital mortality rates of 18.3% vs 17.5%, respectively,... read more

Study Suggests Benefits of Vitamin C for Severe Sepsis

More than 1.7 million Americans develop sepsis every year and incidence of the condition is on the rise. In severe cases, widespread inflammation leads to multiorgan failure and death. Results of a new study hold... read more

Is Intensive Care Becoming an Out-of-hours Acute Palliative Care Service?

First I will define what I conceive medicine to be. In general terms, it is to do away with the sufferings of the sick, to lessen the violence of their diseases, and to refuse to treat those who are overmastered by their... read more

Early Psychological Screening of ICU Survivors

Symptoms of post-traumatic stress, anxiety and depression assessed 1 week after ICU stay correlate with 3-month psychological outcome. The HADS and PTSS-10 may be useful aids to identify ICU survivors at high risk for... read more

Lower Glucose Targets Show Improved Mortality in Cardiac Patients

Tighter glucose control while minimizing the risk of severe hypoglycemia is associated with lower mortality among critically ill cardiac patents, new research suggests. Researchers reported in CHEST on the outcomes of... read more

Critical Care Opioids Impact in the 21st Century

Critical Care is impacted by opioids in multiple ways. Not only do they form the backbone of managing pain and sedation in the intensive care unit (ICU), the burgeoning opioid epidemic also feeds into opioid-related ICU admissions.... read more

ICU Bouncebacks Associated with Worse Outcomes

ICU Bouncebacks (ICUBBs) are associated with worse outcomes and are disproportionately burdened by respiratory complications. These findings emphasize the importance of the TQIP Collaborative in identifying statewide... read more

Impact of a Progressive Mobility Program on the Functional Status, Respiratory and Muscular Systems of ICU Patients

Patients who participated in an ICU mobility program had better functional status at discharge from the ICU. The other benefits of the program included better performance in the mobility tests and improved maximum voluntary... read more

Impact of Natural Light Exposure on Delirium Burden in Adult Patients Receiving Invasive Mechanical Ventilation in the ICU

Admission to a single room with potential exposure to natural light via windows was not associated with reduced delirium burden, as compared to admission to a single room without windows. However, natural light exposure was... read more

Sedation and Analgesia in the ICU

Sedation and analgesia have high importance in patient-centered care. Patients in the ICU are seriously ill and often suffer from anxiety, agitation, and pain. There is sometimes a need to use deep and prolonged sedation,... read more

Tailoring Nutrition Therapy to Illness and Recovery

Without doubt, in medicine as in life, one size does not fit all. We do not administer the same drug or dose to every patient at all times, so why then would we live under the illusion that we should give the same nutrition... read more

The Association Between Ventilator Dyssynchrony, Delivered Tidal Volume, and Sedation Using a Novel Automated Ventilator Dyssynchrony Detection Algorithm

We developed a computerized algorithm that accurately detects three types of ventilator dyssynchrony. Double-triggered and flow-limited breaths are associated with the frequent delivery of tidal volumes of greater than... read more

Influence of Dyskalemia at ICU Admission and Early Dyskalemia Correction on Survival

Dyskalemia is common at ICU admission and associated with increased mortality. Occurrence of cardiac events increased with dyskalemia depth. A correction of serum potassium level by day 2 was associated with improved... read more

Quantitative EEG for Detection of Brain Ischemia

Electroencephalography (EEG) is a very promising tool for monitoring brain function in real-time in the ICU. There are characteristic changes that occur on EEG in response to brain ischemia, correlating with CBF and brain... read more

The Association of Clinical Variables and the Development of Specified Chronic Conditions in ICU Survivors

Clinical variables, especially the reason for ICU admission, are associated with the development of chronic conditions after ICU discharge. Therefore, these clinical variables should be considered when organizing follow-up... read more

Video Laryngoscopy Does Not Improve Intubation Outcomes in Critical Patients

On the basis of the results of this study, we conclude that, compared with direct laryngoscopy, video laryngoscopy does not improve intubation outcomes in emergency and critical patients. Prehospital intubation is even worsened... read more

Effects of Sepsis on Mortality in Critically Ill Patients 2 Years After ICU Discharge

Compared with patients without sepsis, those with sepsis have higher mortality in the intensive care unit and have more pain, hospital readmissions, and functional decline within 2 years after discharge. During the study,... read more

Stress Management Intervention to Prevent PICS-Family in Patients’ Spouses

Sensation Awareness Focused Training (SĀF-T) intervention during the ICU stay is feasible, acceptable, and may improve family caregivers' post-ICU outcomes. Larger clinical trial to assess the effectiveness of SĀF-T in... read more