Neurological Complications After First Dose of COVID-19 Vaccines

Emerging reports of rare neurological complications associated with COVID-19 infection and vaccinations are leading to regulatory, clinical and public health concerns. We undertook a self-controlled case series study to investigate... read more

Neurological Complications After First Dose of COVID-19 Vaccines

CCSC Encourage Flu Shots Amid COVID-19 Spread

The members of the Critical Care Societies Collaborative (CCSC), which includes the American Association of Critical-Care Nurses (AACN), American College of Chest Physicians (CHEST), American Thoracic Society (ATS), and Society... read more

CCSC Encourage Flu Shots Amid COVID-19 Spread

Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia

Carbapenem-based empiric regimens were associated with lower mortality rates compared with non-carbapenems, largely driven by trials of ventilator-associated pneumonia (VAP). The mortality effect was not observed in trials... read more

Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia

Perioperative Dexmedetomidine on the Incidence of Postoperative Delirium

Delirium occurs commonly following major non-cardiac and cardiac surgery and is associated with: postoperative mortality; postoperative neurocognitive dysfunction; increased length of hospital stay; and major postoperative... read more

Perioperative Dexmedetomidine on the Incidence of Postoperative Delirium

Brain–lung Interactions and Mechanical Ventilation in Patients with Isolated Brain Injury

During the last decade, experimental and clinical studies have demonstrated that isolated acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and systems. Of all potential target organs... read more

Brain–lung Interactions and Mechanical Ventilation in Patients with Isolated Brain Injury

Short-term and Long-term Rates of Postacute Sequelae of COVID-19 Infection

In this systematic review, we evaluated the temporal progression of clinical abnormalities experienced by patients who recovered from an infection with SARS-CoV-2, starting with a mean of 30 days post–acute illness and... read more

Short-term and Long-term Rates of Postacute Sequelae of COVID-19 Infection

COVID-19 Handbook: Navigating the Future of Healthcare

The COVID-19 Handbook: Navigating the Future of Healthcare provides factual, evidence-based information on the coronavirus disease 2019 (COVID-19) pandemic. Presented in a concise PDF format, this valuable COVID-19 resource... read more

COVID-19 Handbook: Navigating the Future of Healthcare

Scripts for Subconjunctival Hemorrhage, Fainting and Syncope, and Viral Illness

Many parts of the ED encounter interfere with patient or family comprehension, not the least of which is the ED's noisy, hurried environment. But other factors affect what they understand and remember about the encounter—their... read more

Scripts for Subconjunctival Hemorrhage, Fainting and Syncope, and Viral Illness

We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt

Melbourne’s second wave of COVID-19 last year, which led to a lockdown lasting more than 100 days, provided us with many lessons about controlling transmission. Some of these are pertinent as New South Wales endures its... read more

We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt

Convalescent Plasma for COVID-19 in Hospitalised Patients

Convalescent plasma (CP) and standard of care (SOC) did not result in a higher proportion of clinical improvement on at day 28 in hospitalised patients with COVID-19 compared to SOC alone. This is an investigator-initiated,... read more

Convalescent Plasma for COVID-19 in Hospitalised Patients

COVID-19 Immune Evasion by the B.1.427/B.1.429 Variant of Concern

As battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of concern because they... read more

COVID-19 Immune Evasion by the B.1.427/B.1.429 Variant of Concern

COVID-19 Variant Classifications and Definitions

Genetic variants of SARS-CoV-2 have been emerging and circulating around the world throughout the COVID-19 pandemic. Viral mutations and variants in the United States are routinely monitored through sequence-based surveillance,... read more

COVID-19 Variant Classifications and Definitions

Fungal Infections Complicating COVID-19

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread globally to pandemic proportions. Although the majority of cases have asymptomatic or mild infections,... read more

Fungal Infections Complicating COVID-19

Time Course of Risk Factors Associated with COVID-19 Mortality

The present multicentric study describes 1,260 critically ill patients with COVID-19-associated acute respiratory failure consecutively admitted to 24 Italian ICUs during the first pandemic wave. This study specifically... read more

Time Course of Risk Factors Associated with COVID-19 Mortality

COVID-19 Variants in Patients with Immunosuppression

Patients with immunosuppression are at risk for prolonged infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In several case reports, investigators have indicated that multimutational SARS-CoV-2... read more

COVID-19 Variants in Patients with Immunosuppression

Full Vaccination Suppresses COVID-19 Delta Variant Mutation Frequency

This study presents the first evidence that full vaccination against COVID-19 suppresses emergent mutations of SARS-CoV-2 delta variants. An evolution algorithm, Tajima's D test with a threshold value as -2.50, can provide... read more

Full Vaccination Suppresses COVID-19 Delta Variant Mutation Frequency

NIH-convened Expert Panel Proposes Standardized Definition of Placental COVID-19 Infection

A panel of experts convened by the National Institutes of Health has recommended standardized criteria to define infection of the placenta with SARS-CoV-2, the virus that causes COVID-19. The panel also offers guidance... read more

NIH-convened Expert Panel Proposes Standardized Definition of Placental COVID-19 Infection

The Harriet Lane Handbook: Mobile Medicine Series

Written "by residents, for residents" and reviewed by expert faculty at The Johns Hopkins Hospital, Lauren Kahl, MD and Helen K. Hughes, MD, MPH, The Harriet Lane Handbook, 21st Edition, remains your #1 source of pediatric... read more

The Harriet Lane Handbook: Mobile Medicine Series